Latest publications from the Faculty of Medicine

• Aune, Susanne Kristine; Helseth, Ragnhild Merckoll; Kalstad, Are; Laake, Kristian; Åkra, Sissel & Arnesen, Harald [Show all 8 contributors for this article] (2024). Links Between Adipose Tissue Gene Expression of Gut Leakage Markers, Circulating Levels, Anthropometrics, and Diet in Patients with Coronary Artery Disease. Diabetes, Metabolic Syndrome and Obesity. ISSN 1178-7007. 17, p. 2177–2190. doi: 10.2147/DMSO.S438818.
• Khan, Faraz Hameed; Zhao, Debbie; Ha, Jong-Won; Nagueh, Sherif F.; Voigt, Jens-Uwe & Klein, Allan L. [Show all 28 contributors for this article] (2024). Evaluation of left ventricular filling pressure by echocardiography in patients with atrial fibrillation. Echo Research and Practice. 11(1). doi: 10.1186/s44156-024-00048-x.
• Grinde, Bjørn (2024). How to Form the Human Brain. World Futures. ISSN 0260-4027. doi: 10.1080/02604027.2024.2361141.
• Morton, William James; Hauge, Anton; Opdahl, Helge; Rein, Erling Bekkestad; Søvik, Signe & Hisdal, Jonny (2024). Nine treatments of 1000 mL therapeutic phlebotomy in a subject with polycythemia: A case report. Physiological Reports. ISSN 2051-817X. 12(11). doi: 10.14814/phy2.16035.
• Audunsdottir, Kristin; Sartorius, Alina Marie; Kang, Heemin; Glaser, Bernt Damian; Bøen, Rune & Nærland, Terje [Show all 11 contributors for this article] (2024). The effects of oxytocin administration on social and routinized behaviors in autism: A preregistered systematic review and meta-analysis. Psychoneuroendocrinology. ISSN 0306-4530. 167. doi: 10.1016/j.psyneuen.2024.107067.
• Salihovic, Samira; Nyström, Niklas; Mathisen, Charlotte Bache-Wiig; Kruse, Robert; Olbjørn, Christine & Andersen, Svend [Show all 30 contributors for this article] (2024). Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease. Nature Communications. ISSN 2041-1723. doi: 10.1038/s41467-024-48763-7. Show summary

  Improved biomarkers are needed for pediatric inflammatory bowel disease. Here we identify a diagnostic lipidomic signature for pediatric inflammatory bowel disease by analyzing blood samples from a discovery cohort of incident treatment-naïve pediatric patients and validating findings in an independent inception cohort. The lipidomic signature comprising of only lactosyl ceramide (d18:1/16:0) and phosphatidylcholine (18:0p/22:6) improves the diagnostic prediction compared with high-sensitivity C-reactive protein. Adding high-sensitivity C-reactive protein to the signature does not improve its performance. In patients providing a stool sample, the diagnostic performance of the lipidomic signature and fecal calprotectin, a marker of gastrointestinal inflammation, does not substantially differ. Upon investigation in a third pediatric cohort, the findings of increased lactosyl ceramide (d18:1/16:0) and decreased phosphatidylcholine (18:0p/22:6) absolute concentrations are confirmed. Translation of the lipidomic signature into a scalable diagnostic blood test for pediatric inflammatory bowel disease has the potential to support clinical decision making.

• Miljeteig, Ingrid; Førde, Reidun; Isaksson Rø, Karin Elisabet; Bååthe, Fredrik & Bringedal, Berit (2024). Moral distress among physicians in Norway: a longitudinal study. BMJ Open. ISSN 2044-6055. 14(5). doi: 10.1136/bmjopen-2023-080380.
• Langerud, Jonas; Eilertsen, Ina Andrassy; Moosavi, Hossein; Klokkerud, Solveig Margrete Knoph; Reims, Henrik Mikael & Backe, Ingeborg Flåten [Show all 13 contributors for this article] (2024). Multiregional transcriptomics identifies congruent consensus subtypes with prognostic value beyond tumor heterogeneity of colorectal cancer. Nature Communications. ISSN 2041-1723. 15(1). doi: 10.1038/s41467-024-48706-2.
• Mulrooney, Elisabeth; Neogi, Tuhina; Dagfinrud, Hanne; Hammer, Hilde Berner; Steen Pettersen, Pernille & Kvien, Tore Kristian Aaserud [Show all 8 contributors for this article] (2024). Hand osteoarthritis phenotypes based on a biopsychosocial approach, and their associations with cross-sectional and longitudinal pain. Osteoarthritis and Cartilage. ISSN 1063-4584. doi: 10.1016/j.joca.2024.04.011.
• Torland, Lilly Anne; Lai, Xiaoran; Kumar, Surendra; Riis, Margit; Geisler, Jürgen & Lüders, Torben [Show all 10 contributors for this article] (2024). Benign breast tumors may arise on different immunological backgrounds. Molecular Oncology. ISSN 1574-7891. doi: 10.1002/1878-0261.13655.
• Gebreegziabher, Senedu Bekele; Ashuro, Akililu Alemu; Kumssa, Tsegaye Hailu; Teferi, Melese Yeshambaw; Alemayue, Endawoke Amsalu & Datiko, Daniel Gemechu [Show all 8 contributors for this article] (2024). Tuberculosis preventive treatment uptake among people living with HIV during COVID-19 period in Addis Ababa, Ethiopia: a retrospective data review. BMC Infectious Diseases. ISSN 1471-2334. 24(1). doi: 10.1186/s12879-024-09403-z.
• Shahrouzi, Parastoo; Forouz, Farzaneh; Mathelier, Anthony; Kristensen, Vessela N. & Duijf, Pascal Hubertus Gerardus (2024). Copy number alterations: a catastrophic orchestration of the breast cancer genome. Trends in Molecular Medicine. ISSN 1471-4914. doi: 10.1016/j.molmed.2024.04.017.
• Nahse-Kumpf, Viola; Stenmark, Harald Alfred & Schink, Kay Oliver (2024). Omegasomes control formation, expansion, and closure of autophagosomes. Bioessays. ISSN 0265-9247. 46(6). doi: 10.1002/bies.202400038.
• Edsjö, Anders; Russnes, Hege Elisabeth Giercksky; Lehtiö, Janne; Tamborero, David; Hovig, Eivind & Stenzinger, Albrecht [Show all 65 contributors for this article] (2024). High-throughput molecular assays for inclusion in personalised oncology trials – State-of-the-art and beyond. Journal of Internal Medicine. ISSN 0954-6820. 295(6), p. 785–803. doi: 10.1111/joim.13785.
• Volta, Umberto; Rostami, Kamran; Auricchio, Renata & Lundin, Knut (2024). Diagnosis of Seronegative and Ultrashort Celiac Disease. Gastroenterology. ISSN 0016-5085. doi: 10.1053/j.gastro.2024.01.029.
• Rose, Maddison; Burgess, Joshua T.; Cheong, Chee Man; Adams, Mark N.; Shahrouzi, Parastoo & O’Byrne, Kenneth J. [Show all 8 contributors for this article] (2024). The expression and role of the Lem-D proteins Ankle2, Emerin, Lemd2, and TMPO in triple-negative breast cancer cell growth. Frontiers in Oncology. ISSN 2234-943X. 14. doi: 10.3389/fonc.2024.1222698.
• Kurppa, Kalle; Mulder, Chris J.; Størdal, Ketil & Kaukinen, Katri (2024). Celiac Disease Affects 1% of Global Population—Who Will Manage All These Patients? What Are Criteria to Prioritize Along Risk for Complications? Gastroenterology. ISSN 0016-5085. doi: 10.1053/j.gastro.2023.12.026.
• Panagopoulos, Ioannis; Andersen, Kristin; Stavseth, Vidar; Torkildsen, Synne; Heim, Sverre & Tandsæther, Maren Randi (2024). Germline MYOF1::WNK4 and VPS25::MYOF1 Chimeras Generated by the Constitutional Translocation t(17;19)(q21;p13) in Two Siblings With Myelodysplastic Syndrome. Cancer Genomics & Proteomics. ISSN 1109-6535. 21(3), p. 272–284. doi: 10.21873/cgp.20446.
• Gamboa, Danil; Kabashi, Saranda; Jørgenrud, Benedicte Marie; Lerdal, Anners; Nordby, Gudmund & Bogstrand, Stig Tore (2024). Is alcohol and psychoactive medication use associated with excess hospital length-of-stay and admission frequency? A cross-sectional, observational study. BMC Emergency Medicine. ISSN 1471-227X. 24(1). doi: 10.1186/s12873-024-00979-y.
• Atai, Shahriar; Knudtzon Andersen, Martin; Wiedmann, Markus; Dahlberg, Daniel; Øystese, Kristin Astrid Berland & Bollerslev, Jens [Show all 8 contributors for this article] (2024). Unravelling pituitary tumours in medically treated patients with acromegaly: the impact of systematic MRI reassessment. Acta Radiologica. ISSN 0284-1851. doi: 10.1177/02841851241246107.
• Dubovyk, Violetta; Vasileiadis, Georgios K.; Fatima, Tahzeeb; Zhang, Yuan; Kapetanovic, Meliha Crnkic & Kastbom, Alf [Show all 25 contributors for this article] (2024). Obesity is a risk factor for poor response to treatment in early rheumatoid arthritis: a NORD-STAR study. RMD Open. ISSN 2056-5933. 10(2). doi: 10.1136/rmdopen-2024-004227.
• Ellingsen, Dag; Sikkeland, Liv Ingunn Bjoner; Lund, May Britt; Skaugset, Nils Petter & Ulvestad, Bente (2024). A study of inflammatory biomarkers in crystalline silica exposed rock drillers. International Archives of Occupational and Environmental Health. ISSN 0340-0131. doi: 10.1007/s00420-024-02070-2. Full text in Research Archive
• Kongsgaard, Ulf Erik; Menchini, Robin Johansen; Larsen, Stein Gunnar & Juul-Hansen, Knut Erling (2024). Skin conductance algesimeter is unreliable during sudden perioperative temperature increases. Scandinavian Journal of Pain. ISSN 1877-8860. 24(1). doi: 10.1515/sjpain-2023-0106.
• Ørnbjerg, Lykke Midtbøll; Brahe, Cecilie Heegaard; Linde, Louise; Jacobsson, Lennart; Nissen, Michael J. & Kristianslund, Eirik [Show all 35 contributors for this article] (2024). Drug effectiveness of 2nd and 3rd TNF inhibitors in psoriatic arthritis – relationship with the reason for withdrawal from the previous treatment. Joint Bone Spine. ISSN 1297-319X. 91(4). doi: 10.1016/j.jbspin.2024.105729.
• Stenmarck, Mille Sofie; Whitehurst, David GT; Lurås, Hilde & Rugkåsa, Jorun (2024). “It’s hard to say anything definitive about what severity really is”: lay conceptualisations of severity in a healthcare context. BMC Health Services Research. ISSN 1472-6963. 24(1). doi: 10.1186/s12913-024-10892-6.
• van Osch, Matthias J. P.; Wåhlin, Anders; Scheyhing, Paul; Mossige, Ingrid; Hirschler, Lydiane & Eklund, Anders [Show all 16 contributors for this article] (2024). Human brain clearance imaging: Pathways taken by magnetic resonance imaging contrast agents after administration in cerebrospinal fluid and blood. NMR in Biomedicine. ISSN 0952-3480. doi: 10.1002/nbm.5159.
• Nilsen, Dennis WT; Aarsetoey, Reidun; Poenitz, Volker; Ueland, Thor; Aukrust, Pål & Michelsen, Annika Elisabet [Show all 9 contributors for this article] (2024). Chemokine ligand 18 predicts all-cause mortality in patients hospitalized with chest pain of suspected coronary origin. International Journal of Cardiology: Cardiovascular Risk and Prevention (IJCCRP). ISSN 2772-4875. 21. doi: 10.1016/j.ijcrp.2024.200264.
• Bekkevold, Marit; Solvik-Olsen, Tone; Heyerdahl, Fridtjof; Lang, Astri Maria; Hagemo, Jostein Skjalg & Rehn, Marius (2024). Reporting interhospital neonatal intensive care transport: international five-step Delphi-based template. BMJ Paediatrics Open. ISSN 2399-9772. 8(1). doi: 10.1136/bmjpo-2023-002374.
• Štrumbelj, Erik; Bouchard-Côté, Alexandre; Corander, Jukka; Gelman, Andrew; Rue, Håvard & Murray, Lawrence [Show all 9 contributors for this article] (2024). Past, Present and Future of Software for Bayesian Inference. Statistical Science. ISSN 0883-4237. 39(1), p. 46–61. doi: 10.1214/23-STS907.
• Vallin, Michaela; Tomson, Göran; Kampmann, Beate; Engebretsen, Eivind; Swartling Peterson, Stefan & Wanyenze, Rhoda K. [Show all 7 contributors for this article] (2024). Life Science 2.0: reframing the life science sector for ‘the benefit on mankind’. Global health action. ISSN 1654-9716. 17(1). doi: 10.1080/16549716.2024.2330758.
• Kjørholt, Kaja Eriksrud; Paulshus Sundlisæter, Nina; Aga, Anna-Birgitte; Sexton, Joseph; Olsen, Inge Christoffer & Fremstad, Hallvard [Show all 22 contributors for this article] (2024). Effects of tapering conventional synthetic disease-modifying antirheumatic drugs to drug-free remission versus stable treatment in rheumatoid arthritis (ARCTIC REWIND): 3-year results from an open-label, randomised controlled, non-inferiority trial. The Lancet Rheumatology. doi: 10.1016/S2665-9913(24)00021-3.
• Roehr, Charles Christoph; Szczapa, Tomasz; Stiris, Tom; Hadjipanayis, Adamos; Koletzko, Berthold & Ross-Russell, Rob [Show all 9 contributors for this article] (2024). European Training Requirements in Neonatology 2021: The ESPR, EAP, and UEMS Accredited European Syllabus for Neonatal Training. Neonatology. ISSN 1661-7800. doi: 10.1159/000536247.
• Jølstad, Odd Borgar; Stenmarck, Mille Sofie & Barra, Mathias (2024). Preparing popular views for inclusion in a reflective equilibrium: A case study on illness severity. Social Science and Medicine. ISSN 0277-9536. 348. doi: 10.1016/j.socscimed.2024.116794.
• Huynh, Thuy-Tien Maria; Falk, Ragnhild Sørum; Hellebust, Taran Annette Paulsen; Dale, Einar; Astrup, Guro Lindviksmoen & Hjermstad, Marianne Jensen [Show all 12 contributors for this article] (2024). Chronic fatigue in long-term survivors of head and neck cancer treated with radiotherapy. Radiotherapy and Oncology. ISSN 0167-8140. 195. doi: 10.1016/j.radonc.2024.110231.
• Andresen, Kristoffer; Klæboe, Lars Gunnar; Lie, Øyvind Haugen; Broch, Kaspar; Kvaslerud, Anette Borger & Bosse, Gerhard [Show all 10 contributors for this article] (2024). No adverse association between exercise exposure and diffuse myocardial fibrosis in male endurance athletes. Scientific Reports. ISSN 2045-2322. 14(1). doi: 10.1038/s41598-024-57233-5.
• Nilsbakken, I.M.W.; Wisborg, Torben; Sollid, Stephen J. M. & Jeppesen, Elisabeth (2024). Functional outcome and associations with prehospital time and urban-remote disparities in trauma: A Norwegian national population-based study. Injury. ISSN 0020-1383. doi: 10.1016/j.injury.2024.111459.
• Haugen, Morten; Magnussen, Karin; Aarsland, Tonje Eiane; Nissen-Meyer, Lise Sofie Haug & Strand, Tor Arne (2024). The effect of donation frequency on donor health in blood donors donating plasma by plasmapheresis: study protocol for a randomized controlled trial. Trials. ISSN 1745-6215. 25(1). doi: 10.1186/s13063-024-08035-7.
• Stenmarck, Mille Sofie; Whitehurst, David GT.; Baker, Rachel & Barra, Mathias (2024). Charting public views on the meaning of illness severity. Social Science and Medicine. ISSN 0277-9536. 347. doi: 10.1016/j.socscimed.2024.116760.
• Sæther, Linn Sofie; Szabo, Attila; Akkouh, Ibrahim Ahmed; Haatveit, Beathe ; Mohn, Christine & Vaskinn, Anja [Show all 14 contributors for this article] (2024). Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain. Brain, Behavior, and Immunity. ISSN 0889-1591. 118, p. 287–299. doi: 10.1016/j.bbi.2024.03.014.
• Klæboe, Lars Gunnar; Lie, Øyvind Haugen; Brekke, Pål Haugar; Bosse, Gerhard; Hopp, Einar & Haugaa, Kristina Ingrid Helena Hermann [Show all 7 contributors for this article] (2024). Differentiation of Myocardial Properties in Physiological Athletic Cardiac Remodeling and Mild Hypertrophic Cardiomyopathy. Biomedicines. 12(2). doi: 10.3390/biomedicines12020420.
• Wang, He-Ling; Siow, Richard; Schmauck-Medina, Tomas; Zhang, Jianying; Sandset, Per Morten & Filshie, Clare [Show all 38 contributors for this article] (2024). Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies. The journals of gerontology. Series A, Biological sciences and medical sciences. ISSN 1079-5006. 79(4). doi: 10.1093/gerona/glae029.
• Fredheim, Olav Magnus Søndenå; Torvund, Solveig Kristine Kolstad; Thoresen, Lisbeth & Magelssen, Morten (2024). How should respiratory depression and loss of airway patency be handled during initiation of palliative sedation? Acta Anaesthesiologica Scandinavica. ISSN 0001-5172. doi: 10.1111/aas.14396.
• Subbotina, Anna; Skjølsvik, Eystein; Solbu, Marit Dahl; Miroslawska, Atena & Steigen, Terje Kristian (2024). Echocardiographic findings following renal sympathetic denervation for treatment resistant hypertension, the ReShape CV-risk study. Blood Pressure. ISSN 0803-7051. 33(1). doi: 10.1080/08037051.2024.2326298.
• Larsen, Johanne Hartwedt; Andersen, Svend; Perminow, Gøri Margrete; Mundal, Håkon Stangeland; Mårild, Karl Staffan & Stabell, Niklas [Show all 7 contributors for this article] (2024). Higher incidence of paediatric inflammatory bowel disease by increasing latitude in Norway, but stable incidence by age. Acta Paediatrica. ISSN 0803-5253. doi: 10.1111/apa.17222.
• Wu, Chenyu; Gunnarsson, Einar Bjarki; Myklebust, Even Moa; Luque, Alvaro Kohn; Tadele, Dagim Shiferaw & Enserink, Jorrit [Show all 9 contributors for this article] (2024). Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data. PLoS Computational Biology. ISSN 1553-734X. 20(3). doi: 10.1371/journal.pcbi.1011888.

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• Netteland, Dag Ferner; Aarhus, Mads; Sandset, Else Charlotte; Padayachy, Llewellyn; Helseth, Eirik & Brekken, Reidar (2024). In Reply: Possible Factors Missed While Assessing Optic Nerve Sheath Diameter and Deformability Index in Patients with Severe Traumatic Brain Injury. Neurocritical Care. ISSN 1541-6933. doi: 10.1007/s12028-024-02015-0.
• Taso, Mirad & Brox, Jens Ivar (2024). Letter to the editor regarding “Patient expectations impact patient-reported outcomes and satisfaction after lumbar fusion” by Zhang et al. The spine journal. ISSN 1529-9430. 24(7). doi: 10.1016/j.spinee.2024.02.025.
• Nestaas, Eirik; BJARKØ, LISA; Kiserud, Torvid; Haugen, Guttorm Nils & Fugelseth, Drude (2024). Corrigendum to “Heart function by M-mode and tissue Doppler in the early neonatal period in neonates with fetal growth restriction”, [Early Hum. Dev. 183 (2023) 105809] (Early Human Development (2023) 183, (S0378378223001056), (10.1016/j.earlhumdev.2023.105809)). Early Human Development. ISSN 0378-3782. doi: 10.1016/j.earlhumdev.2024.106032.
• Netteland, Dag Ferner; Næss, Pål Aksel; Gaarder, Aslaug Christine & Helseth, Eirik (2024). Letter to the editor. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. ISSN 1757-7241. 32(1). doi: 10.1186/s13049-024-01199-w.
• Gløersen, Marthe; Steen Pettersen, Pernille; Maugesten, Øystein Gunnar; Mulrooney, Elisabeth; Mathiessen, Alexander & Gammelsrud, Heidi [Show all 14 contributors for this article] (2024). Corrigendum to “Study protocol for the follow-up examination of the Nor-Hand study: A hospital-based observational cohort study exploring pain and biomarkers in people with hand osteoarthritis” [Osteoarthr. Cartil. Open 3 (2021) 100198] (Osteoarthritis and Cartilage Open (2021) 3(3), (S2665913121000613), (10.1016/j.ocarto.2021.100198)). Osteoarthritis and Cartilage Open. ISSN 2665-9131. 6(1). doi: 10.1016/j.ocarto.2022.100274.

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