Guro Haugen Fossum

• Frey Esgård, Veronica; Lindman, Ida; Brænd, Anja Maria; Fossum, Guro Haugen; Lundberg, Thorbjörn & Moberg, Anna [Show all 9 contributors for this article] (2024). Diagnostic methods and written advice for acute otitis media in primary health care. Scandinavian Journal of Primary Health Care. ISSN 0281-3432. doi: 10.1080/02813432.2024.2352444.
• Skonnord, Trygve; Brænd, Anja Maria Lyche & Fossum, Guro Haugen (2024). Pasienterfaringer med fastlegetjenesten under covid-19-pandemien – en tverrsnittsstudie. Tidsskrift for velferdsforskning. ISSN 0809-2052. doi: 10.18261/tfv.27.1.3. Full text in Research Archive
• Heltveit-Olsen, Silje Rebekka; Lunde, Lene; Brænd, Anja Maria; Spehar, Ivan; Høye, Sigurd & Sundvall, Pär-Daniel [Show all 10 contributors for this article] (2024). Local management of the COVID-19 pandemic in Norway: a longitudinal interview study of municipality chief medical officers. Scandinavian Journal of Primary Health Care. ISSN 0281-3432. 42(1), p. 214–224. doi: 10.1080/02813432.2023.2301562. Full text in Research Archive
• Fossum, Guro Haugen; Brænd, Anja Maria; Heltveit-Olsen, Silje Rebekka; Rørtveit, Guri; Høye, Sigurd & Straand, Jørund (2023). Symptoms, symptom severity, and contact with primary health care among nonhospitalized COVID-19 patients: a Norwegian web-based survey. Scandinavian Journal of Primary Health Care. ISSN 0281-3432. 41(4), p. 427–434. doi: 10.1080/02813432.2023.2266477. Full text in Research Archive Show summary

  Objective Dependent on clinical setting, geography and timing during the pandemic, variable symptoms of COVID-19 have been reported. Our aim was to describe self-reported symptom intensity and contact with primary health care among nonhospitalized COVID-19 patients. Design Web-based survey. Setting Norway between March 2020 and July 2021. Subjects Adults in home isolation. Main outcome measures Participants reported possible COVID-19 symptoms, duration of symptoms, score of symptom severity (Likert scale 0–3), risk factors, comorbidity, and questions regarding follow-up and information from primary health care. Results Of 477 participants, 379 (79%) had PCR-confirmed COVID-19, 324 (68%) were females, and 90% were younger than 60 years. Most common symptoms were “fatigue and/or muscle ache” (80%), nasal symptoms (79%), and headache (73%). The mean severity of symptoms was generally low. Symptoms with the highest mean scores were “fatigue and/or muscle ache” (1.51, SD 1.02) and headache (1.27 (SD 1.00). Mean scores for severity ranged from 0.28 (nausea) to 1.51 (fatigue and/or muscle ache). Women reported higher symptom scores than men. For “affected sense of smell and/or taste”, patients either reported a high symptom score (24%) or no affliction at all (49%). A third of the participants (32%) were followed-up by primary care health personnel, and almost 40% had sought or received information about COVID-19 from general practitioners. Conclusion The mean severity of symptoms among nonhospitalized adult COVID-19 patients was generally low. We found large variations in the occurrence and severity of symptoms between patients.

• Skow, Marius Andre Hybbestad; Fossum, Guro Haugen; Høye, Sigurd; Straand, Jørund; Brænd, Anja Maria & Emilsson, Louise (2023). Hospitalizations and severe complications following acute sinusitis in general practice: a registry-based cohort study. Journal of Antimicrobial Chemotherapy. ISSN 0305-7453. 78(9), p. 2217–2227. doi: 10.1093/jac/dkad227. Full text in Research Archive
• Forthun, Ingeborg; Rørtveit, Guri; Fossum, Guro Haugen; Jørgensen, Pål; Halvorsen, Peder Andreas & Nilsen, Stein [Show all 9 contributors for this article] (2023). Søvnforstyrrelser og forskrivning av hypnotika i allmennpraksis – en PraksisNett-studie. SØVN. ISSN 1891-5493. p. 11–15. Full text in Research Archive Show summary

  Søvnforstyrrelser er svært utbredt i befolkningen. Insomni er den vanligste søvnforstyrrelsen med en forekomst på omkring 10-20 %. Forekomsten ser ut til å være økende i befolkningen. Blant pasienter på venterommet hos norske fastleger er forekomsten så høy som rundt 50 % ifølge to tidligere studier. Insomni utgjør en risikofaktor for utvikling av psykiske lidelser og er identifisert som en mulig kausal årsaksfaktor for en rekke negative helseutfall. Selv om sovemedisiner kun er anbefalt ved akutte søvnplager, er forskrivning av sovemedisiner også for langvarige plager svært vanlig. Medikamentgruppen hypnotika inkluderer benzodiazepiner, benzodiazepinlignende sovemidler (z preparater) og melatoninpreparater. I klinisk praksis benyttes av og til også andre preparater enn hypnotika mot søvnproblemer, inkludert antidepressiva, antihistaminer og antipsykotika.

• Skow, Marius; Fossum, Guro Haugen; Høye, Sigurd; Straand, Jørund; Emilsson, Louise & Brænd, Anja Maria (2023). Antibiotic treatment of respiratory tract infections in adults in Norwegian general practice. JAC-Antimicrobial Resistance (JAC-AMR). ISSN 2632-1823. 5(1). doi: 10.1093/jacamr/dlac135. Full text in Research Archive
• Heltveit-Olsen, Silje Rebekka; Lunde, Lene; Brænd, Anja Maria Lyche; Spehar, Ivan; Høye, Sigurd & Skoglund, Ingmarie [Show all 10 contributors for this article] (2022). Experiences and management strategies of Norwegian GPs during the COVID-19 pandemic: a longitudinal interview study. Scandinavian Journal of Primary Health Care. ISSN 0281-3432. doi: 10.1080/02813432.2022.2142796. Full text in Research Archive
• Kristoffersen, Espen Saxhaug; Bjorvatn, Bjørn; Halvorsen, Peder Andreas; Nilsen, Stein; Fossum, Guro Haugen & Fors, Egil Andreas [Show all 12 contributors for this article] (2022). The Norwegian PraksisNett: a nationwide practice-based research network with a novel IT infrastructure. Scandinavian Journal of Primary Health Care. ISSN 0281-3432. 40(2), p. 217–226. doi: 10.1080/02813432.2022.2073966. Full text in Research Archive Show summary

  Clinical research in primary care is relatively scarce. Practice-based research networks (PBRNs) are research infrastructures to overcome hurdles associated with conducting studies in primary care. In Norway, almost all 5.4 million inhabitants have access to a general practitioner (GP) through a patient-list system. This gives opportunity for a PBRN with reliable information about the general population. The aim of the current paper is to describe the establishment, organization and function of PraksisNett (the Norwegian Primary Care Research Network). Materials and Methods We describe the development, funding and logistics of PraksisNett as a nationwide PBRN. Results PraksisNett received funding from the Research Council of Norway for an establishment period of five years (2018–2022). It is comprised of two parts; a human infrastructure (employees, including academic GPs) organized as four regional nodes and a coordinating node and an IT infrastructure comprised by the Snow system in conjunction with the Medrave M4 system. The core of the infrastructure is the 92 general practices that are contractually linked to PraksisNett. These include 492 GPs, serving almost 520,000 patients. Practices were recruited during 2019–2020 and comprise a representative mix of rural and urban settings spread throughout all regions of Norway. Conclusion Norway has established a nationwide PBRN to reduce hurdles for conducting clinical studies in primary care. Improved infrastructure for clinical studies in primary care is expected to increase the attractiveness for studies on the management of disorders and diseases in primary care and facilitate international research collaboration. This will benefit both patients, GPs and society in terms of improved quality of care.

• Fossum, Guro Haugen; Lindbæk, Morten; Gjelstad, Svein & Kvaerner, Kari Jorunn (2018). Relationship between Maternal and First Year of Life Dispensations of Antibiotics and Antiasthmatics. Antibiotics. ISSN 2079-6382. 7(3). doi: 10.3390/antibiotics7030084. Full text in Research Archive
• Fossum, Guro Haugen; Gjelstad, Svein; Kvaerner, Kari Jorunn & Lindbæk, Morten (2018). Prescribing antibiotics when the stakes are higher — do GPs prescribe less when patients are pregnant? A retrospective observational study. British Journal of General Practice Open. ISSN 2398-3795. 2(2), p. 1–12. doi: 10.3399/bjgpopen18X101505. Full text in Research Archive Show summary

  Background Most oral antibiotics are prescribed by GPs, and they are therefore the most important influencers with regard to improving antibiotic prescription patterns. Although GPs’ prescription patterns in general are well-studied, little is known about antibiotic prescription patterns in pregnancy. Aim To study GPs’ antibiotic prescriptions in respiratory tract infections (RTIs) during pregnancy, and assess differences, if any, between pregnant and non-pregnant patients. Design & setting Retrospective observational study combining prescription data from the Norwegian Peer Academic Detailing (Rx-PAD) study database, pregnancy data from the Norwegian birth registry, and pharmacy dispension data from the Norwegian Prescription Database (NorPD). Method Records of patient contacts with 458 GPs, between December 2004 and February 2007, were screened for RTI episodes. Similar diagnoses were grouped together, as were similar antibiotics. Episodes were categorised according to whether the patient was pregnant or not, and included women aged 16–46 years. Logistic regression models were used to assess odds ratios (ORs), and calculated relative risks (cRRs) were produced. The authors also adjusted for clustering at various levels. Results Overall prescription rate for RTI episodes was 30.8% (n = 96 830). The cohort was reduced to include only episodes with women pregnant in the study period (n = 18 890). The antibiotic prescription rate in pregnancy was 25.9% versus 34.2% in the time before and after pregnancy (cRR = 0.66 [95% confidence intervals {CI} = 0.68 to 0.81]). During pregnancy, 83.0% of the antibiotic prescriptions were picked up at a pharmacy, compared to an 86.6% filling rate in non-pregnant patients. The difference was not significant when adjusting for clustering at the patient level. Conclusion Norwegian GPs prescribe fewer antibiotics overall when patients are pregnant and, when they do prescribe, choose more narrow spectrum antibiotics for RTIs. This indicates a possible lower target rate for GP prescriptions to females. A low antibiotic dispension rate during pregnancy may represent a discussion topic in the consultation setting, to address possible reasons and avoid under-treatment.

• Fossum, Guro Haugen; Lie, Agnes Kathrine; Jebsen, Peter Wilhelm; Sandlie, Lars Eriks & Mork, Jon (2017). Human papillomavirus in oropharyngeal squamous cell carcinoma in South-Eastern Norway: prevalence, genotype, and survival. European Archives of Oto-Rhino-Laryngology. ISSN 0937-4477. 274(11), p. 4003–4010. doi: 10.1007/s00405-017-4748-8.
• Denstad, Silje Eilertsen; Aasen, Silja; Østrem, Anette; Bakkeheim, Vivi; Fossum, Guro Haugen & Moen, Mette Haase (2017). Hysterektomi ved St. Olavs hospital 1989-2014. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 137(16). doi: 10.4045/tidsskr.16.0260. Full text in Research Archive
• Fossum, Guro Haugen; Lindbæk, Morten; Gjelstad, Svein; Dalen, Ingvild & Kvaerner, Kari Jorunn (2013). Are children carrying the burden of broad-spectrum antibiotics in general practice? Prescription pattern for paediatric outpatients with respiratory tract infections in Norway. BMJ Open. ISSN 2044-6055. 3(1). doi: 10.1136/bmjopen-2012-002285.

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• Skow, Marius; Emilsson, Louise; Straand, Jørund; Høye, Sigurd & Fossum, Guro Haugen (2024). Complicated courses of sinusitis in general practice in an era of antibiotic stewardship.
• Renaa, Therese; Emilsson, Louise; Skow, Marius; Høye, Sigurd & Fossum, Guro Haugen (2023). Antibiotic prescriptions to preschool children with respiratory tract infections in Norwegian primary health care 2012-2019.
• Fossum, Guro Haugen & Halvorsen, Peder Andreas (2023). PraksisNett - et forskningsnettverk i primærhelsetjenesten.
• Fossum, Guro Haugen & Halvorsen, Peder Andreas (2023). Using information technology to facilitate research in a practice-based research network - the story of PraksisNett.
• Skow, Marius; Fossum, Guro Haugen; Høye, Sigurd; Straand, Jørund; Brænd, Anja Maria & Emilsson, Louise (2023). Antibiotic Treatment of Respiratory Tract Infections in Adults in Norwegian General Practice.
• Skow, Marius; Fossum, Guro Haugen; Høye, Sigurd; Straand, Jørund; Emilsson, Louise & Brænd, Anja Maria (2022). Antibiotic treatment of adult patients with respiratory tract infections in Norwegian general practice: A nationwide registry-based study.
• Svaland, Malene; Brænd, Anja Maria Lyche & Fossum, Guro Haugen (2022). CovidNor - The Patient Study.
• Fossum, Guro Haugen; Brænd, Anja Maria Lyche; Heltveit-Olsen, Silje Rebekka; Høye, Sigurd; Rørtveit, Guri & Straand, Jørund (2022). CovidNor - The Patient Study.
• Skonnord, Trygve; Brænd, Anja Maria & Fossum, Guro Haugen (2022). Patient experiences from the COVID-19 pandemic regarding health care seeking, self-care, concern for disease, and delayed diagnosis and treatment; a cross-sectional study in general practice.
• Heltveit-Olsen, Silje Rebekka; Lunde, Lene; Brænd, Anja Maria; Spehar, Ivan; Høye, Sigurd & Skoglund, Ingmarie [Show all 10 contributors for this article] (2022). Experiences and management strategies of Norwegian GPs during the COVID-19 pandemic: A longitudinal interview study. .
• Fors, Egil Andreas; Rørtveit, Guri; Bellika, Johan Gustav; Nilsen, Stein; Fossum, Guro Haugen & Bjorvatn, Bjørn (2022). Practice-based research networks: A small step for a GP, but a giant leap for primary care research.
• Fossum, Guro Haugen; Heltveit-Olsen, Silje Rebekka & Høye, Sigurd (2020). Experiences of patients and primary health care professionals during the COVID-19 epidemic in Norway .
• Fossum, Guro Haugen (2019). Infeksjoner og antibiotikabruk hos gravide og hos småbarn.
• Fossum, Guro Haugen; Brænd, Anja Maria; Høye, Sigurd & Minge, Christina (2019). European Treatment Guidelines for Otitis, Sinusitis and Tonsillitis in Primary Care.
• Fossum, Guro Haugen (2019). RESPIRATORY TRACT INFECTIONS AND PRESCRIPTION DRUGS IN MOTHER AND CHILD - A STUDY FROM NORWEGIAN GENERAL PRACTICE.
• Fossum, Guro Haugen (2018). Relationship between maternal antibiotic prescriptions and antibiotic and antiasthmatic prescriptions in children younger than one year .
• Fossum, Guro Haugen (2013). Antibiotika til barn -et spørsmål om smak og behag. Utposten. ISSN 0800-5680. 2, p. 6–7.
• Fossum, Guro Haugen & Hjortdal, Per (2013). Streptokokkhalsinfeksjon og skarlagensfeber, Nasjonale retningslinjer for antibiotikabruk i primærhelsetjenesten. Helsedirektoratet. ISSN 978-82-8081-271-1. p. 73–78.
• Fossum, Guro Haugen (2019). RESPIRATORY TRACT INFECTIONS AND PRESCRIPTION DRUGS IN MOTHER AND CHILD - A STUDY FROM NORWEGIAN GENERAL PRACTICE. Universitetet i Oslo.

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