Maren Falch Lindberg

• Rognsvåg, Turid; Buset Bergvad, Ingvild; Furnes, Ove Nord; Indrekvam, Kari; Lerdal, Anners & Lindberg, Maren Falch [Vis alle 9 forfattere av denne artikkelen] (2024). Exercise therapy, education, and cognitive behavioral therapy alone, or in combination with total knee arthroplasty, in patients with knee osteoarthritis: a randomized feasibility study. BMC Pilot and Feasibility Studies. ISSN 2055-5784. 10(1). doi: 10.1186/s40814-024-01470-y.
• Olsen, Unni Solveig Johansen; Sellevold, Vibeke Bull; Gay, Caryl; Aamodt, Arild; Lerdal, Anners & Småstuen, Milada Cvancarova [Vis alle 8 forfattere av denne artikkelen] (2024). Factors associated with pain and functional impairment five years after total knee arthroplasty: a prospective observational study. BMC Musculoskeletal Disorders. ISSN 1471-2474. 25(1). doi: 10.1186/s12891-023-07125-y. Fulltekst i vitenarkiv
• Enbakom, Mestawet Getachew; Lerdal, Anners; Småstuen, Milada Cvancarova; Eshete, Million Tesfaye; Desta, Tilahun & Lindberg, Maren Falch (2023). Modifiable factors associated with a consistently high acute pain trajectory after surgical treatment of traumatic fractures in Ethiopia: a multi-center prospective cohort study. Journal of Orthopaedic Surgery and Research. ISSN 1749-799X. 18(1). doi: 10.1186/s13018-023-03770-0. Fulltekst i vitenarkiv
• Sellevold, Vibeke Bull; Olsen, Unni ; Lindberg, Maren Falch; Steindal, Simen Alexander; Aamodt, Arild & Lerdal, Anners [Vis alle 7 forfattere av denne artikkelen] (2023). “I am accustomed to something in my body causing pain”: A qualitative study of knee replacement non-improvers’ stories of previous painful and stressful experiences. BMC Musculoskeletal Disorders. ISSN 1471-2474. 24(1). doi: 10.1186/s12891-023-06423-9. Fulltekst i vitenarkiv
• Olsen, Unni ; Lindberg, Maren Falch; Rose, Christopher James; Denison, Eva Marie-Louise; Gay, Caryl & Aamodt, Arild [Vis alle 11 forfattere av denne artikkelen] (2023). Factors correlated with pain after total knee arthroplasty: A systematic review and meta-analysis. PLOS ONE. ISSN 1932-6203. 18(3). doi: 10.1371/journal.pone.0283446. Fulltekst i vitenarkiv
• Getachew, Mestawet ; Lerdal, Anners; Småstuen, Milada Cvancarova; Gay, Caryl; Aamodt, Arild & Tesfaye, Million [Vis alle 7 forfattere av denne artikkelen] (2022). Worst pain intensity and opioid intake during the early postoperative period were not associated with moderate-severe pain 12 months after total knee arthroplasty - a longitudinal study. Scandinavian Journal of Pain. ISSN 1877-8860. doi: 10.1515/sjpain-2022-0007. Fulltekst i vitenarkiv
• Olsen, Unni ; Lindberg, Maren Falch; Rose, Christopher James; Denison, Eva Marie-Louise; Gay, Caryl & Aamodt, Arild [Vis alle 11 forfattere av denne artikkelen] (2022). Factors Correlated with Physical Function 1 Year after Total Knee Arthroplasty in Patients with Knee Osteoarthritis: A Systematic Review and Meta-analysis. JAMA Network Open. ISSN 2574-3805. 5(7), s. 1–15. doi: 10.1001/jamanetworkopen.2022.19636. Fulltekst i vitenarkiv
• Sellevold, Vibeke Bull; Steindal, Simen Alexander; Lindberg, Maren Falch; Småstuen, Milada Cvancarova; Aamodt, Arild & Lerdal, Anners [Vis alle 7 forfattere av denne artikkelen] (2022). Many Patients with Persistent Pain One Year After TKA Report Improvement by 5-7 years: A Mixed Methods Study . Clinical Orthopaedics and Related Research. ISSN 0009-921X. 480(11), s. 2075–2088. doi: 10.1097/CORR.0000000000002183. Fulltekst i vitenarkiv
• Lindberg, Maren Falch; Aamodt, Arild; Badawy, Mona; Bergvad, Ingvild Buset; Borchgrevink, Petter Chr. & Furnes, Ove Nord [Vis alle 21 forfattere av denne artikkelen] (2021). The effectiveness of exercise therapy and education plus cognitive behavioral therapy, alone or in combination with total knee arthroplasty in patients with knee osteoarthritis – study protocol for the MultiKnee trial. BMC Musculoskeletal Disorders. ISSN 1471-2474. 22:1054, s. 1–14. doi: 10.1186/s12891-021-04924-z. Fulltekst i vitenarkiv Vis sammendrag

  Background One in five patients report chronic pain following total knee arthroplasty (TKA) and are considered non-improvers. Psychological interventions such as cognitive behavioral therapy (CBT), combined with exercise therapy and education may contribute to reduced pain an improved function both for patients with OA or after TKA surgery, but the evidence for the effectiveness of such interventions is scarce. This randomized controlled trial with three arms will compare the clinical effectiveness of patient education and exercise therapy combined with internet-delivered CBT (iCBT), evaluated either as a non-surgical treatment choice or in combination with TKA, in comparison to usual treatment with TKA in patients with knee OA who are considered candidates for TKA surgery. Methods The study, conducted in three orthopaedic centers in Norway will include 282 patients between ages 18 and 80, eligible for TKA. Patients will be randomized to receive the exercise therapy + iCBT, either alone or in combination with TKA, or to a control group who will undergo conventional TKA and usual care physiotherapy following surgery. The exercise therapy will include 24 one hour sessions over 12 weeks led by a physiotherapist. The iCBT program will be delivered in ten modules. The physiotherapists will receive theoretical and practical training to advise and mentor the patients during the iCBT program. The primary outcome will be change from baseline to 12 months on the pain sub-scale from the Knee Injury and Osteoarthritis Outcome Score (KOOS). Secondary outcomes include the remaining 4 sub-scales from the KOOS (symptoms, function in daily living, function in sports and recreation, and knee-related quality of life), EQ-5D-5L, the Pain Catastrophizing Scale, the 30-s sit-to-stand test, 40-m walking test and ActiGraph activity measures. A cost-utility analysis will be performed using QALYs derived from the EQ-5D-5L and registry data. Discussion This is the first randomized controlled trial to investigate the effectiveness of exercise therapy and iCBT with or without TKA, to optimize outcomes for TKA patients. Findings from this trial will contribute to evidence-based ersonalized treatment recommendations for a large proportion of OA patients who currently lack an effective treatment option. Trial registration Clinicaltrials.gov: NCT03771430. Registered: Dec 11, 2018.

• Rognsvåg, Turid; Lindberg, Maren Falch; Lerdal, Anners; Stubberud, Jan Egil; Furnes, Ove Nord & Holm, Inger [Vis alle 11 forfattere av denne artikkelen] (2021). Development of an internet-delivered cognitive behavioral therapy program for use in combination with exercise therapy and education by patients at increased risk of chronic pain following total knee arthroplasty. BMC Health Services Research. ISSN 1472-6963. 21(1), s. 1–14. doi: 10.1186/s12913-021-07177-7. Fulltekst i vitenarkiv
• Lindberg, Maren Falch; Miaskowski, Christine; Rustøen, Tone; Cooper, Bruce A.; Aamodt, Arild & Lerdal, Anners (2020). Preoperative risk factors associated with chronic pain profiles following total knee arthroplasty. European Journal of Pain. ISSN 1090-3801. s. 1–13. doi: 10.1002/ejp.1703. Fulltekst i vitenarkiv
• Enbakom, Mestawet Getachew; Lerdal, Anners; Småstuen, Milada Cvancarova; Gay, Caryl; Aamodt, Arild & Tesfaye, Million [Vis alle 7 forfattere av denne artikkelen] (2020). High levels of preoperative pain and fatigue are red flags for moderate‐severe pain 12 months after total knee arthroplasty—A longitudinal cohort study. Musculoskeletal Care. ISSN 1478-2189. s. 1–7. doi: 10.1002/msc.1522. Fulltekst i vitenarkiv Vis sammendrag

  Background: Moderate/severe pain after total knee arthroplasty (TKA) is a poor surgical outcome. Many studies have identified preoperative risk factors of painafter TKA, but studies of the joint contributions of co-occurring symptoms arelacking. Methods: Patients undergoing primary TKA (n=202) were enrolled in a longitu-dinal cohort study. Preoperatively, patients completed questionnaires measuring demographics and symptoms (pain, fatigue, sleep problems and depression). Painwas re-assessed 12 months after TKA. Logistic regression analysis was used to compute the probabilities of moderate-severe pain at 12 months based on preoperative symptom levels, and results were combined into a risk matrix. Results: More than one-third (40%) of patients (n=187) reported moderate-severepain after TKA. Among preoperative risk factors included in the logistic regressionanalyses were age, sex, pain, fatigue, sleep problems and depression. Adjusting forpossible confounders, fatigue (p=0.02) and pain (p=0.01) were significant riskfactors for moderate-severe pain at 12-months follow-up and were retained in the final risk matrix. The co-occurrence of high-preoperative fatigue and pain scores resulted in 57% estimated probability of moderate-severe pain at 12 months.Similarly, the co-occurrence of low-preoperative fatigue and pain scores resulted in14% estimated probability of moderate-severe pain 12 months after TKA. Conclusion: The combination of high fatigue and pain scores prior to surgery was akey risk factor for moderate-severe pain 12 months after TKA. Mapping of these factors could be used preoperatively to identify patients who are at risk to expe-rience a poor outcome of TKA.

• Olsen, Unni Solveig Johansen; Lindberg, Maren Falch; Denison, Eva Marie-Louise; Rose, Christopher James; Gay, Caryl & Aamodt, Arild [Vis alle 11 forfattere av denne artikkelen] (2020). Predictors of chronic pain and level of physical function in total knee arthroplasty: a protocol for a systematic review and meta-analysis. BMJ Open. ISSN 2044-6055. 10, s. 1–9. doi: 10.1136/bmjopen-2020-037674. Fulltekst i vitenarkiv Vis sammendrag

  Abstract Introduction One in five patients undergoing total knee arthroplasty (TKA) experience unchanged or worse pain and physical function 1 year after surgery. Identifying risk factors for unfavourable outcomes is necessary to develop tailored interventions to minimise risk. There is a need to review more current literature with updated methodology that addresses the limitations of earlier systematic reviews and meta-analyses. We present a Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols compliant protocol for a systematic review and meta-analysis of predictors of chronic pain and impaired function after TKA. Methods and analysis This review will include prospective longitudinal observational studies, or randomised trials (including cluster and crossover designs) that report arm-wise predictors of chronic postsurgical pain or impaired physical function at 3 months, 6 months or 12 months. A comprehensive literature search of studies published between 2000 and 2019 will be performed in Medline, Embase, CINAHL, Cochrane Library and PEDro. Blinded assessment with consensus agreement will be applied for inclusion of studies, data extraction and assessment of bias risk (Quality in Prognosis Studies tool). The co-primary outcomes, pain and impaired function, at 12 months after TKA will be analysed separately. Estimates of association between each outcome and any preoperative or intraoperative factor that may predict chronic pain or impaired physical function will be extracted from the included studies, where possible. For randomised studies, results will only be extracted from TKA arms (or the first period of crossover trials). Estimates of association from the primary evidence will be synthesised narratively, and quantitatively using multivariate meta-analysis to provide ‘pooled’ estimates of association. Subgroup and sensitivity analyses will be performed. Certainty of evidence for each predictor will be derived from the Grading of Recommendations Assessment, Development and Evaluation framework. Ethics and dissemination No ethical issues are associated with this project. The results from this review will be published in peer-reviewed journals and presented at international conferences.

• Rehman, Yasser; Lindberg, Maren Falch; Arnljot, Kristine; Gay, Caryl; Lerdal, Anners & Aamodt, Arild (2020). More severe radiographic osteoarthritis is associated with increased improvements in patients' health state following a total knee arthroplasty. Journal of Arthroplasty. ISSN 0883-5403. 35(11). doi: 10.1016/j.arth.2020.06.025. Fulltekst i vitenarkiv Vis sammendrag

  Background To assess whether preoperative radiological severity of osteoarthritis (OA) is related to the level of improvement in patients’ health state measured 1 year after total knee arthroplasty (TKA). Methods Radiographic severity of OA was graded using the Kellgren-Lawrence (KL) classification. Two independent observers were blinded to patients’ outcome scores. Health-related quality of life was measured using EQ-5D-3L preoperatively and at 12-month follow-up. The 5 dimensions of the EQ-5D were converted into a health state index score. The association between KL grade and improvement in health state score was analyzed using multiple linear regression. Results Among 156 consecutive patients (68% females, mean age 69 years) who underwent primary TKA, 3 knees (2%) were classified as KL grade 2, 115 as KL grade 3 (74%), and 38 as KL grade 4 (24%). Follow-up rate was 77%. There was substantial intra-rater and inter-rater agreement (Cohen’s kappa = 0.80 and 0.79). Most patients (64%) had clinically significant improvement in their health state score 1 year after TKA. However, after adjusting for relevant covariates, patients with severe OA (KL grade 4) were found to have significantly more improvement in their health state score than patients with mild or moderate OA (KL grade 2 or 3, respectively). Separate analysis of the 5 EQ-5D dimensions showed that the KL group differences were most evident in the “usual activities” and “pain/discomfort” dimensions. Conclusion Patients with severe OA have significantly more improvement in their usual activities and pain/discomfort 1 year after TKA than patients with less severe OA.

• Bragstad, Line Kildal; Lerdal, Anners Vetle; Gay, Caryl L.; Kirkevold, Marit; Lee, Kathryn A. & Lindberg, Maren Falch [Vis alle 10 forfattere av denne artikkelen] (2020). Psychometric properties of a short version of Lee Fatigue Scale used as a generic PROM in persons with stroke or osteoarthritis: assessment using a Rasch analysis approach. Health and Quality of Life Outcomes. ISSN 1477-7525. 18, s. 1–8. doi: 10.1186/s12955-020-01419-8. Fulltekst i vitenarkiv
• Lindberg, Maren Falch; Schweitz, Turid Undebakke; Aamodt, Arild; Gay, Caryl & Lerdal, Anners (2020). High pre- and postoperative symptom burden in non-responders to total knee arthroplasty. PLOS ONE. ISSN 1932-6203. 15(5)(5), s. 1–14. doi: 10.1371/journal.pone.0233347. Vis sammendrag

  Objectives One in five patients does not improve in pain with walking (non-responders) 12 months after total knee arthroplasty (TKA). This longitudinal study investigated a broad range of symptoms before and after TKA and evaluated possible differences in symptom distress between responders and non-responders with regards to pain with walking after TKA. Methods Prior to TKA surgery, 182 patients completed a demographic questionnaire and the Memorial Symptom Assessment Scale—Short Form (MSAS-SF). The MSAS-SF was repeated 12 months following TKA. Clinical data were extracted from medical records. Patients were categorized as responders or non-responders based on their trajectories of pain with walking assessed prior to surgery, on postoperative day 4, at 6 weeks, and at 3 and 12 months. Results Overall, the most distressful preoperative symptoms were pain, lack of energy, difficulty sleeping, feeling drowsy, worrying, feeling bloated, and problems with sexual interest or activity. However, compared with patients classified as responders to TKA, non-responders had higher total symptom distress scores both preoperatively and 12 months postoperatively. Preoperatively, non-responders scored higher than responders on five of the seven most distressing symptoms (i.e., all except difficulty sleeping and feeling bloated), and 12 months postoperatively, non-responders scored higher than responders on six of the seven most distressing symptoms (i.e., all but feeling bloated). In a multivariate analysis, higher preoperative distress scores for pain and problems with sexual interest or activity were significant predictors of non-response to TKA, controlling for other relevant factors. Conclusions Patients’ preoperative symptom burden may be a useful indicator of their risk for nonimprovement following TKA surgery. Future studies need to evaluate the effect of reducing patients’ preoperative symptom burden on TKA outcomes

• Kornilov, Nikolai; Lindberg, Maren Falch; Gay, Caryl; Saraev, Alexander; Kuliaba, Taras & Rosseland, Leiv Arne [Vis alle 7 forfattere av denne artikkelen] (2017). Higher physical activity and lower pain levels before surgery predict non-improvement of knee pain 1 year after TKA. Knee Surgery, Sports Traumatology, Arthroscopy. ISSN 0942-2056. 26(6), s. 1698–1708. doi: 10.1007/s00167-017-4713-5.
• Saraev, Alexander; Lindberg, Maren Falch; Gay, Caryl; Rosseland, Leiv Arne; Lerdal, Anners & Kornilov, Nikolai [Vis alle 7 forfattere av denne artikkelen] (2017). What influence on early postoperative pain intensity after total knee arthorplasty? Travmatologiya i Ortopediya Rossii. ISSN 2311-2905. 23(1), s. 46–58. doi: 10.21823/2311-2905-2017-23-1-45-58. Fulltekst i vitenarkiv Vis sammendrag

  Purpose: To describe the relationship of selected socio-demographic, clinical, and surgical factors with the severity and patterns of postoperative pain during the first three days following total knee arthroplasty. Material and methods. The sample included 100 patients (93 women and 7 men; mean age 63.5±7.8 years) with osteoarthritis admitted for primary total knee arthroplasty. Prior to surgery, standard measures were used to assess preoperative pain and other symptoms, clinical manifestations of osteoarthritis, functional status of the knee, comorbidities, functional abilities, quality of life, and other patient characteristics. Patterns of daily changes in postoperative pain characteristics were investigated with the use of individual diaries. Results. All the analyzed indicators of postoperative pain progressively decreased during the three days after surgery (p<.001), including the number of daily hours of moderate to severe pain (p<.001). Pain levels were generally higher among women than among men (p=.009). Of the analyzed preoperative factors, higher levels postoperative pain were correlated with higher levels of anxiety (p=.029) and preoperative pain intensity (p=.029). Among the perioperative factors, surgery duration longer than 90 minutes was associated with higher levels of postoperative pain in activity (p=.012) and more hours of moderate/severe pain (p=.008). Characteristics of postoperative pain were unrelated to level of patient education, social or family status, employment, lifestyle, or any other clinical or laboratory variables. Conclusion. Of the many factors previously associated with postoperative pain, only gender, anxiety and level of preoperative pain confirmed their importance in this study. Among the perioperative factors, surgery duration, which varied by the type of implant, was significantly associated with postoperative pain Levels.

• Lindberg, Maren Falch; Rustøen, Tone; Christine, Miaskowski; Rosseland, Leiv Arne & Lerdal, Anners (2017). The relationship between pain with walking and self-rated health 12 months following total knee arthroplasty: a longitudinal study. BMC Musculoskeletal Disorders. ISSN 1471-2474. 18(1). doi: 10.1186/s12891-017-1430-7. Fulltekst i vitenarkiv
• Lindberg, Maren Falch; Miaskowski, Christine; Rustøen, Tone; Rosseland, Leiv Arne; Cooper, Bruce A. & Lerdal, Anners (2016). Factors that can predict pain with walking, 12 months after total knee arthroplasty: A trajectory analysis of 202 patients. Acta Orthopaedica. ISSN 1745-3674. 87(6), s. 600–606. doi: 10.1080/17453674.2016.1237440.
• Lindberg, Maren Kristin Falch; Miaskowski, Christine; Rustøen, Tone; Rosseland, Leiv Arne; Cooper, Bruce A. & Lerdal, Anners (2016). Factors that can predict pain with walking, 12 months after total knee arthroplasty - A trajectory analysis of 202 patients. Acta Orthopaedica. ISSN 1745-3674. 87(6), s. 600–606. doi: 10.1080/17453674.2016.1237440. Fulltekst i vitenarkiv Vis sammendrag

  Background and purpose — Functional limitations after total knee arthroplasty (TKA) are common. In this longitudinal study, we wanted to identify subgroups of patients with distinct trajectories of pain-related interference with walking during the first year after TKA and to determine which demographic, clinical, symptom-related, and psychological characteristics were associated with being part of this subgroup. Patients and methods — Patients scheduled for primary TKA for osteoarthritis (n = 202) completed questionnaires that evaluated perception of pain, fatigue, anxiety, depression, and illness on the day before surgery. Clinical characteristics were obtained from the medical records. Interference of pain with walking was assessed preoperatively, on postoperative day 4, and at 6 weeks, 3 months, and 12 months after TKA.

• Lindberg, Maren Kristin Falch; Miaskowski, Christine; Rustøen, Tone; Rosseland, Leiv Arne; Paul, Steven M. & Lerdal, Anners (2016). Preoperative pain, symptoms, and psychological factors related to higher acute pain trajectories during hospitalization for total knee arthroplasty. PLOS ONE. ISSN 1932-6203. 11(9). doi: 10.1371/journal.pone.0161681. Fulltekst i vitenarkiv Vis sammendrag

  Objectives Unrelieved postoperative pain after total knee arthroplasty (TKA) is a significant problem. This longitudinal study investigated how preoperative pain intensity, as well as a comprehensive list of preoperative and perioperative factors, influenced the severity of acute average and worst pain after TKA. Methods Prior to surgery, 203 patients completed a demographic questionnaire, Lee Fatigue Scale, Fatigue Severity Scale, Hospital Anxiety and Depression Scale, and Brief Illness Perception Questionnaire. Brief Pain Inventory was completed prior to surgery as well as through postoperative days (POD) 0 to 4. Clinical data were extracted from medical records. Results Several factors were associated with higher levels of preoperative and postoperative pain. Lower preoperative average and worst pain intensity scores were associated with increases in average and worst postoperative pain from POD1 to POD4. A higher number of comorbidities, higher C-reactive protein values, and higher pain interference with function were associated with higher preoperative levels of average pain. Older age, higher fatigue levels, and higher scores on identity and emotional responses to osteoarthritis (OA) were associated with higher preoperative levels of worst pain. Lower perceived consequences of OA were associated with higher pain from POD1 to POD4. Males and patients with lower preoperative scores for average pain had higher worst pain following surgery. Discussion Patients at higher risk for more severe postoperative pain can be identified through an assessment of pain and other risk factors identified in this study. Future research needs to test the efficacy of interventions that modify patients’ perceptions of living with OA and pain intensity before surgery on short and long term postoperative outcomes.

• Lindberg, Maren Kristin Falch; Miaskowski, Christine; Rustøen, Tone; Rosseland, Leiv Arne; Paul, Steven M. & Cooper, Bruce A. [Vis alle 7 forfattere av denne artikkelen] (2016). The Impact of Demographic, Clinical, Symptom and Psychological Characteristics on the Trajectories of Acute Postoperative Pain After Total Knee Arthroplasty. Pain medicine (Malden, Mass.). ISSN 1526-2375. doi: 10.1093/pm/pnw080.
• Kornilov, Nikolai; Lindberg, Maren Kristin Falch; Gay, Caryl; Saraev, Alexander; Kuliaba, Taras & Rosseland, Leiv Arne [Vis alle 8 forfattere av denne artikkelen] (2016). Factors Related to Postoperative Pain Trajectories following Total Knee Arthroplasty: A Longitudinal Study of Patients Admitted to a Russian Orthopaedic Clinic. Pain Research and Treatment. ISSN 2090-1542. 2016. doi: 10.1155/2016/3710312. Fulltekst i vitenarkiv
• Lindberg, Maren-Kristin Falch; Grov, Ellen Karine; Gay, Caryl; Rustøen, Tone; Granheim, Tove Irene & Amlie, Einar Johan Braém [Vis alle 7 forfattere av denne artikkelen] (2013). Pain characteristics and self-rated health after elective orthopaedic surgery – a cross-sectional survey. Journal of Clinical Nursing (JCN). ISSN 0962-1067. 22(9-10), s. 1242–1253. doi: 10.1111/jocn.12149. Vis sammendrag

  Aims and objectives. To describe the postoperative pain and to examine the relationship between pain intensity, pain interference and self-rated health after elective orthopaedic surgery. Background. Pain is a problem for many surgical inpatients and can lead to postoperative complications. Limited knowledge exists about the relationship between postoperative pain, function and self-rated health. Design. Cross-sectional survey. Methods. Pain characteristics, self-rated health, sociodemographic status and comorbidity were measured in 123 elective orthopaedic inpatients recruited consecutively from a hospital in eastern Norway in 2012. On the day they were discharged from the surgical unit, patients completed items about pain intensity and pain interference from the Brief Pain Inventory and about self-rated health from the Medical Outcome Short Form-36 Health Survey. Clinical data were retrieved from the medical records. Patients were divided into three diagnostic groups: shoulder surgery, hip or knee replacement and other surgery. Results. Mean age was 60 years (SD 17.2) and 50 percent were females. Average pain intensity was 4.2 (SD 2.2) on a 0–10 numeric rating scale and 60 percent reported moderate/severe pain during the entire hospital stay. Shoulder surgery patients reported significantly higher pain intensity compared to other surgical groups. Pain interfered mostly with daily activity and sleep. Higher pain intensity was significantly associated with poorer self-rated health. The linear regression analysis showed that average pain intensity was related to poorer self-rated health, controlling for sociodemographic variables and pain interference with function. Conclusion. High pain intensity is related to poorer self-rated health. Postoperative pain is undermanaged, affects functional areas and could delay rehabilitation. Relevance to clinical practice. Postoperative pain management should be given high priority after elective orthopaedic surgery, in order to improve self-rated health and function. Pain treatment for shoulder surgery patients may require more attention than it currently receives.

Se alle arbeider i Cristin

• Rognsvåg, Turid; Kismul Nordmo, Ingrid; Buset Bergvad, Ingvild; Fenstad, Anne Marie; Furnes, Ove Nord & Lerdal, Anners [Vis alle 9 forfattere av denne artikkelen] (2024). Digital health literacy in patients undergoing hip and knee arthroplasty surgery.
• Lindberg, Maren Falch; Aamodt, Arild; Badawy, Mona; Bergvad, Ingvild Buset; Furnes, Ove Nord & Gay, Caryl [Vis alle 13 forfattere av denne artikkelen] (2024). Education, exercise therapy and iCBT for patients with knee osteoarthritis - the MultiKnee trial.
• Nordmo, Ingrid Kismul; Lindberg, Maren Falch; Bergvad, Ingvild Buset; Gay, Caryl & Lerdal, Anners (2024). Digital health literacy and sociodemographic factors in patients with hip and knee OA.
• Bergvad, Ingvild Buset; Lerdal, Anners & Lindberg, Maren Falch (2024). Body mass index and physical activity in patients undergoing total knee arthroplasty – a prospective cohort study.
• Bergvad, Ingvild Buset; Kottorp, Anders; Aamodt, Arild; Lerdal, Anners; Skou, Søren Thorgaard & Lindberg, Maren Falch (2023). Translation and validation of the Norwegian version of a brief satisfaction measure for use in patients undergoing total joint arthroplasty.
• Olsen, Unni ; Lindberg, Maren Falch; Rose, Christopher James; Denison, Eva Marie-Louise; Gay, Caryl & Aamodt, Arild [Vis alle 11 forfattere av denne artikkelen] (2023). BMI, Physical Function And Osteoarthritis Severity Correlate With Physical Function One Year After Total Knee Arthroplasty: A Systematic Review And Meta-Analysis.
• Sellevold, Vibeke Bull; Steindal, Simen Alexander; Lindberg, Maren Falch; Småstuen, Milada Cvancarova; Aamodt, Arild & Lerdal, Anners [Vis alle 7 forfattere av denne artikkelen] (2022). ‘"Smerter ett år etter kneprotese? Det kan fremdeles være utsikter til bedring’.
• Rognsvåg, Turid; Buset Bergvad, Ingvild; Furnes, Ove Nord; Indrekvam, Kari; Lerdal, Anners & Lindberg, Maren Falch [Vis alle 9 forfattere av denne artikkelen] (2022). Effekt av trening, undervisning og kognitiv adferdsterapi for artrosepasienter med eller uten totalprotese i kne: En randomisert feasibility studie.
• Rognsvåg, Turid; Lindberg, Maren Falch; Lerdal, Anners; Furnes, Ove Nord; stubberud, jan & Holm, Inger [Vis alle 11 forfattere av denne artikkelen] (2022). Development of an internet-delivered cognitive behavioral therapy program for use in combination with exercise therapy and education by patients at increased risk of chronic pain following total knee arthroplasty .
• Sellevold, Vibeke Bull; Steindal, Simen Alexander; Lindberg, Maren Falch; Småstuen, Milada Cvancarova; Aamodt, Arild & Lerdal, Anners [Vis alle 7 forfattere av denne artikkelen] (2022). Many patients with persistent pain one year after total knee arthroplasty report improvement by 5-7 years.
• Lindberg, Maren Falch; Lerdal, Anners; Kise, Nina Jullum; Ludvigsen, Eirin Sigurdssøn; Rognsvåg, Turid & Bergvad, Ingvild Buset (2022). Maren Falch Lindberg, seniorforsker i MultiKnee.
• Sellevold, Vibeke Bull; Lindberg, Maren Falch; Steindal, Simen Alexander; Småstuen, Milada Cvancarova; Aamodt, Arild & Dihle, Alfhild (2021). Persistent pain in patients reporting pain one year after total knee arthroplasty – a follow-up mixed methods study. Vis sammendrag

  BACKGROUND: Approximately 20% of the patients report pain twelve months after total knee arthroplasty (TKA) (1). The aim of this study was to explore the patients  experiences of living with persistent postoperative pain up to seven years after primary TKA, with the following research question: How does persistent postsurgical pain influence everyday life for TKA patients from one year up to seven years after surgery? MATERIAL AND METHODS: The study is part of a longitudinal study of pain, symptoms, and healthrelated quality of life in patients who underwent TKA for osteoarthritis at Lovisenberg Diaconal Hospital in Oslo, Norway (1). The present study targeted the subgroup of patients (22%) from the longitudinal study that reported persistent pain interference with walking 12 months after surgery, the pain levels were the same as preoperatively. This follow-up study employed an explanatory sequential mixed methods design in which both quantitative and qualitative methods were combined and integrated. Data was collected through Brief Pain Inventory combined with a semi-structured interview guide. We collected data on 23 patients, thus only descriptive and non-parametric statistics were employed. Individual semi-structured interviews were conducted five to seven years after surgery. Interviews were analyzed using qualitative content analysis. RESULTS: Mean age at surgery for the participants was 66 years. There was a statistically significant decrease in pain from preoperative to five years after surgery, and from 12 months after surgery to five years after surgery. The qualitative data analysis yielded three themes: Still facing limitations after TKA, Regaining wellness over time and Complexity of bodily challenges. According to the participants  experiences and their medical history, more painful sites and comorbidity, factors that are associated with higher levels of pain at 12 months, seem to interfere with regaining wellness over time. Insecurity of the knee and certain limitations in everyday life, i.e. with high impact sports, seem to be some of the negative consequences that remain, when belonging to this subgroup. CONCLUSION: Follow-up beyond 12 months revealed better pain outcomes over time for the participants in the subgroup who report pain 12 months after TKA. Persistent post-surgical pain, albeit causing certain limitations, seems to be experienced as less influential in everyday lives 5-7 years after primary knee replacement. Comorbidity and a history of more painful sites entail worse prognosis.

• Steindal, Simen Alexander; Lindberg, Maren Falch; Aamodt, Arild; Småstuen, Milada Cvancarova; Lerdal, Anners & Dihle, Alfhild (2021). Persistent pain in patients reporting pain one year after total knee arthroplasty – a follow-up mixed methods study .
• Lindberg, Maren Falch (2021). A multidisciplinary intervention in total knee arthroplasty - a multicenter randomized controlled trial in patients on waiting list for TKA (The MultiKnee trial).
• Lindberg, Maren Falch (2021). MAGIC and Lovisenberg. Enhancing the evidence ecosystem, for increased value and reduced waste in health care.
• Ludvigsen, Eirin Sigurdssøn; Lindberg, Maren Falch; Aamodt, Arild; Lerdal, Anners; Bergvad, Ingvild Buset & Frøyen Lillegård, Julianne Helene (2021). Hva kan jeg forvente dersom jeg bli med i MultiKnee studien?
• Schweitz, Turid Undebakke; Lindberg, Maren Falch; Aamodt, Arild; Gay, Caryl & Lerdal, Anners (2021). Preoperative symptoms as risk factors for non-response to total knee arthroplasty.
• Rehman, Yasser; Lindberg, Maren Falch; Arnljot, Kristine; Gay, Caryl; Lerdal, Anners & Aamodt, Arild (2021). More Severe Radiographic Osteoarthritis Is Associated With Increased Improvement in Patients’ Health State Following a Total Knee Arthroplasty.
• Føllesdal, Andreas; Lindberg, Maren Falch; Neupane, Sudan; Østbakken, Kjersti Misje; Harstad, Stine & Shah, Feroz Mehmood [Vis alle 9 forfattere av denne artikkelen] (2021). Fulbrightprogrammet fyller 75 år. Khrono.no. ISSN 1894-8995.
• Lindberg, Maren Falch; Miaskowski, Christine; Rustøen, Tone; Cooper, Bruce A; Aamodt, Arild & Lerdal, Anners (2021). Chronic pain profiles and associated risk factors following total knee arthroplasty - a prospective observational study.
• Ludvigsen, Eirin Sigurdssøn; Lindberg, Maren Falch; Bergvad, Ingvild Buset; Aamodt, Arild; Lerdal, Anners & Rognsvåg, Turid (2021). Bakgrunn for MultiKnee studien.
• Lindberg, Maren Falch (2021). Fra praksissykepleier til forsker i praksis. I Rustøen, Tone & Lerdal, Anners (Red.), Klinisk forskning innen helsefag. Fagbokforlaget. ISSN 9788245022926. s. 141–152.
• Lindberg, Maren Falch; Rustøen, Tone; Cooper, Bruce A; Aamodt, Arild & Lerdal, Anners Vetle (2021). Authors’ reply to the comment by Riddle et al. European Journal of Pain. ISSN 1090-3801. doi: 10.1002/ejp.1756.
• Lindberg, Maren Falch; Rognsvåg, Turid; Badawy, Mona; Borchgrevink, Petter Chr.; Furnes, Ove & Gay, Caryl [Vis alle 13 forfattere av denne artikkelen] (2019). Optimal behandling av artrosepasienter - en feasibilitystudie (MultiKnee trial).
• Lindberg, Maren Falch (2019). Which patients do not benefit from total knee replacement? .
• Olsen, Unni Solveig Johansen; Berget, Geir; Saunes, Jorunn & Lindberg, Maren Falch (2019). Hvilken betydning har veilederkompetanse for opplevelse av veilederrollen for sykepleiestudenter med praksis i spesialisthelsetjenesten.
• Rognsvåg, Turid; Lindberg, Maren Falch; Borchgrevink, Petter Chr.; Furnes, Ove; Gay, Caryl & Holm, Inger [Vis alle 13 forfattere av denne artikkelen] (2018). Multi-Knee Trial. En feasibilty-studie av en intervensjon for artrosepasienter med økt risiko for langvarige smerter etter operasjon med kneprotese.
• Lindberg, Maren Falch; Witzøe, Andreas & Rognsvåg, Turid (2018). Ny studie: Vil se på alternativer til operasjon med kneprotese. [Fagblad]. Fysioterapeuten.
• Sletten, Rebecca Helene; Lindberg, Maren Falch & Olsen, Unni Solveig Johansen (2018). Pasienters erfaringer med poliklinisk operasjon for karpaltunnelsyndrom.
• Kornilov, Nikolai; Lindberg, Maren Falch; Gay, Caryl; Saraev, Alexander; Kuliaba, Taras & Rosseland, Leiv Arne [Vis alle 7 forfattere av denne artikkelen] (2018). Høyere fysisk aktivitetsnivå og mindre preoperative smerter predikerer manglende forbedring etter innsetting av total kneprotese. Revmatologi BestPractice.
• Lindberg, Maren Falch; Rustøen, Tone; Rosseland, Leiv Arne & Lerdal, Anners (2018). Preoperative prediktorer for smerteforløp og livskvalitet etter kneproteseoperasjon.
• Schweitz, Turid Undebakke; Lindberg, Maren Falch; Ludvigsen, Eirin Sigurdssøn & Lerdal, Anners (2018). Preoperative symptomer hos kneprotesepasienter med tilbakevendende smerter ved gange.
• Lindberg, Maren Falch; Rustøen, Tone; Rosseland, Leiv Arne & Lerdal, Anners (2018). Smerter ved gange og selvrapportert helse etter innsatt kneprotese.
• Lindberg, Maren Falch; Aamodt, Arild & Lerdal, Anners (2018). A multidisciplinary intervention in total knee arthroplasty - a multicenter randomized controlled trial in patients on waiting list for TKA (The MULTI-KNEE trial).
• Lindberg, Maren Falch; Rustøen, Tone; Rosseland, Leiv Arne & Lerdal, Anners (2016). Prediktorer for nedsatt gangfunksjon ett år etter innsatt kneprotese – en subgruppeanalyse.
• Lindberg, Maren Falch; Rustøen, Tone; Rosseland, Leiv Arne & Lerdal, Anners (2016). Smertepåvirkning av gangfunksjon gjennom det første året etter innsatt total kneprotese.
• Lindberg, Maren Falch; Kornilov, Nikolai; Saraev, Alexander; Rosseland, Leiv Arne; Rustøen, Tone & Miaskowski, Christine [Vis alle 8 forfattere av denne artikkelen] (2016). Pain trajectories and patient satisfaction after TKA: results of a two-center Russian-Norwegian study.
• Lindberg, Maren Falch; Miaskowski, Christine; Rustøen, Tone; Rosseland, Leiv Arne; Cooper, Bruce A. & Lerdal, Anners (2016). Trajectories of pain with walking after total knee arthroplasty in two subgroups of patients.
• Lindberg, Maren Falch; Miaskowski, Christine; Rustøen, Tone; Rosseland, Leiv Arne; Paul, Steven M. & Cooper, Bruce A. [Vis alle 7 forfattere av denne artikkelen] (2016). Trajectories of pain, interference With function and quality of life after total knee arthroplasty.
• Lindberg, Maren Kristin Falch; Miaskowski, Christine; Rustøen, Tone; Rosseland, Leiv Arne; Cooper, Bruce A. & Lerdal, Anners (2015). Pain trajectories after total knee replacement.
• Lindberg, Maren Kristin Falch; Miaskowski, Christine; Rustøen, Tone; Rosseland, Leiv Arne; Paul, Steven M & Cooper, Bruce A. [Vis alle 7 forfattere av denne artikkelen] (2015). Trajectories of pain, interference with function and quality of life after total knee arthroplasty.
• Sørstrøm, Anne Kristine; Lindberg, Maren Kristin Falch & Lerdal, Anners (2015). I hvilken grad samsvarer pasienters selvrapporterte smerteintensitet med registreringer utført av sykepleiere?
• Lindberg, Maren Kristin Falch (2014). Vi trenger brukervennlige IKT-løsninger. Sykepleien Forskning. ISSN 1890-2936. s. 53–53.
• Lindberg, Maren-Kristin Falch (2013). Smerter etter ortopedisk kirurgi - hva kan sykepleiere bidra med? Ortonytt. s. 14–16.
• Lindberg, Maren-Kristin Falch; Grov, Ellen Karine; Gay, Caryl; Rustøen, Tone; Granheim, Tove Irene & Amlie, Einar Johan Braém [Vis alle 7 forfattere av denne artikkelen] (2013). Pain characteristics and self-rated health in elective orthopedic surgery patients.
• Lindberg, Maren-Kristin Falch; Grov, Ellen Karine; Rustøen, Tone; Gay, Caryl; Granheim, Tove Irene & Amlie, Einar Johan Braém [Vis alle 7 forfattere av denne artikkelen] (2013). Smerter og deres påvirkning på funksjon etter elektiv ortopedisk kirurgi, konsekvenser for sykepleiepraksis.
• Lindberg, Maren Falch (2012). Smerter og deres påvirkning på funksjon etter elektiv ortopedisk kirurgi - konsekvenser for sykepleiepraksis.
• Lindberg, Maren Falch; Grov, Ellen Karine; Granheim, Tove Irene; Amlie, Einar Johan Braém; Rustøen, Tone & Egeland, Merete [Vis alle 8 forfattere av denne artikkelen] (2012). Smerter og deres påvirkning av funksjon etter elektiv ortopedisk kirurgi – en tverrsnittsurvey. Vis sammendrag

  Bakgrunn Moderate til sterke postoperative smerter har relativt høy prevalens. Dette er et problem for pasientene som kan føre til forlenget liggetid i sykehus og postoperative komplikasjoner. Vi kjenner ikke til tidligere kartlegging av smerteprevalens etter elektiv ortopedisk kirurgi i Norge. Hensikt: Beskrive prevalens av smerte, variasjon i smerteintensitet relatert til pasientenes sosiodemografisk bakgrunn, og smertens påvirkning på funksjon. Metode Data ble samlet fortløpende ved hjelp av spørreskjema hos 123 pasienter ved utskriving fra kirurgisk klinikk ved et sykehus i Østlandsområdet. Spørreskjemaet omfattet sosiodemografisk bakgrunn, samsykdom og smerteerfaringer. Spørsmål om smerter og funksjon ble hentet fra det validerte spørreskjemaet Brief Pain Inventory. Smerteintensitet ble selvrapportert på en 11- punkts Numerisk Rating Scale (NRS). NRS ≥4 ble definert som moderate til sterke smerter/behandlingstrengende smerter. Kliniske data ble hentet fra pasientjournalene. Resultat Deltakernes alder var gjennomsnittlig 60 år, og varierte fra 20-89 år. Halvparten (62) kvinner. Gjennomsnittlig liggetid var 3,7 døgn. Pasientene gjennomgikk ulike typer skulderkirurgi (42), total hofte- og kneprotesekirurgi (62), og diverse kne- og ankelkirurgi (19). Gjennomsnittlig smerte var 4,2 (SD=2,2) og 59% (73) rapporterte NRS≥4 i gjennomsnitt i hele den postoperative fasen. Varighet av smerter ≥4 var i gjennomsnitt 6,4 timer (SD=6,9). Analysene viste ingen signifikant forskjell i smerteintensitet relatert til kjønn, alder og utdanningsnivå. Skulderpasientene rapporterte mest smerter både i hvile og i aktivitet, i gjennomsnitt 4,9 (SD=1,9). Funksjonsområdene ”daglig aktivitet” og ”søvn” var funksjonene som var mest påvirket for hele utvalget, og mest hos skulderpasientene. Konklusjon: Flertallet av pasientene rapporterer om moderate til sterke smerter etter elektiv ortopedisk kirurgi.

• Lindberg, Maren Falch (2012). Abstrakt om kritisk tenkning. Sykepleien Forskning. ISSN 1890-2936. 7(1), s. 85–85.
• Lindberg, Maren-Kristin Falch; Granheim, Tove Irene; Egeland, Merete Trollsås; Amlie, Einar Johan Braém; Rustøen, Tone & Kottorp, Anders [Vis alle 8 forfattere av denne artikkelen] (2012). Smerter og helserelatert livskvalitet hos pasienter som får implantert total kneprotese.
• Rose, Christopher James; Olsen, Unni ; Lindberg, Maren Falch; Denison, Eva Marie-Louise; Aamodt, Arild & Lerdal, Anners (2020). A new multivariate meta-analysis model for many variates and few studies. arXiv.
• Olsen, Unni Solveig Johansen; Lerdal, Anners; Aamodt, Arild; Brox, Jens Ivar; Furnes, Ove & Denison, Eva Marie-Louise [Vis alle 8 forfattere av denne artikkelen] (2018). Preoperative and intraoperative predictors of persistent postoperative pain and impaired physical function in total knee arthroplasty - a systematic review of prognostic studies. PROSPERO, International prospective register of systematic reviews.
• Lindberg, Maren Falch; Lerdal, Anners; Rustøen, Tone & Rosseland, Leiv Arne (2017). Factors that predict the trajectories of aucte pain, pain with walking, and self-rated health after total knee arthroplasty - a longitudinal study. Reprosentralen, Universitetet i Oslo. ISSN 978-82-8377-122-0.

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