Alexandra Aizenshtadt

Researcher - Centre of Excellence - Hybrid Technology Hub

Email alexandra.aizenshtadt@medisin.uio.no

Username

Download business card

Academic interests

iPSC differentiation, disease modeling Microfluidic, 3D and organotypic in vitro culture models.

Background

Postdoctoral Fellowship. Oslo University Hospital HF, Norwegian Center for Stem Cell Research. Advisor: prof. Joel Glover. (Modeling of amyotrophic lateral sclerosis with iPSCs-derived motor neurons, muscle cells and astrocytes and application of microfluidic culture systems)
Head of the Cell Culture Laboratory, Stem Cell Bank Pokrovsky, St-Petersburg, Russia (Development and optimization of MSC isolation, processing, expansion, differentiation. Quality control and assurance, stem cells potency testing, development of ATMP)
PhD, Cell Biology. St-Petersburg State University, Russia (PhD thesis: “Experimental assay of functionality of mesenchymal stem cells from different tissues”)

Hrušková, Helena; Olsen, Christine; Řemínek, Roman; Wang, Chencheng; Aizenshtadt, Aleksandra & Krauss, Stefan Johannes Karl [Show all 10 contributors for this article] (2024). Preparative agarose gel electrophoresis for reducing matrix interferences of organoid cell medium prior to LC-MS analysis of insulin. Journal of Chromatography A. ISSN 0021-9673. 1717. doi: 10.1016/j.chroma.2024.464669.
Aizenshtadt, Aleksandra; Wang, Chencheng; Abadpour, Shadab; Menezes, Pedro Duarte; Wilhelmsen, Ingrid & Dalmao-Fernandez, Andrea [Show all 15 contributors for this article] (2024). Pump-Less, Recirculating Organ-on-Chip (rOoC) Platform to Model the Metabolic Crosstalk between Islets and Liver. Advanced Healthcare Materials. ISSN 2192-2640. doi: 10.1002/adhm.202303785.
Wang, Chencheng; Abadpour, Shadab; Olsen, Petter Angell; Wang, Daxin; Stokowiec, Justyna & Chera, Simona [Show all 11 contributors for this article] (2024). Glucose Concentration in Regulating Induced Pluripotent Stem Cells Differentiation Toward Insulin-Producing Cells. Transplant International. ISSN 0934-0874. 37. doi: 10.3389/ti.2024.11900.
Cunha, André; Schülke, Christin; Mesri, Alireza; Ruud, Simen Kristoffer; Aizenshtadt, Aleksandra & Ferrari, Giorgio [Show all 16 contributors for this article] (2024). Development of a Smart Wireless Multisensor Platform for an Optogenetic Brain Implant. Sensors. ISSN 1424-8220. 24(2). doi: 10.3390/s24020575.
Olsen, Christine; Wang, Chencheng; Aizenshtadt, Aleksandra; Abadpour, Shadab; Lundanes, Elsa & Skottvoll, Frøydis Sved [Show all 11 contributors for this article] (2023). Simultaneous LC–MS determination of glucose regulatory peptides secreted by stem cell–derived islet organoids. Electrophoresis. ISSN 0173-0835. 44(21-22), p. 1682–1697. doi: 10.1002/elps.202300095. Full text in Research Archive
Wilhelmsen, Ingrid; Amirola Martinez, Mikel; Stokowiec, Justyna; Wang, Chencheng; Aizenshtadt, Aleksandra & Krauss, Stefan Johannes Karl (2023). Characterization of human stem cell-derived hepatic stellate cells and liver sinusoidal endothelial cells during extended in vitro culture. Frontiers in Bioengineering and Biotechnology. ISSN 2296-4185. 11. doi: 10.3389/fbioe.2023.1223737. Full text in Research Archive
Kømurcu, Kristina Sæterdal; Wilhelmsen, Ingrid; Thorne, James L.; Krauss, Stefan Johannes Karl; Wilson, Steven Ray Haakon & Aizenshtadt, Aleksandra [Show all 7 contributors for this article] (2023). Mass spectrometry reveals that oxysterols are secreted from non-alcoholic fatty liver disease induced organoids. Journal of Steroid Biochemistry and Molecular Biology. ISSN 0960-0760. 232. doi: 10.1016/j.jsbmb.2023.106355. Full text in Research Archive
Dalmao-Fernandez, Andrea; Aizenshtadt, Aleksandra; Bakke, Hege Gilbø; Krauss, Stefan Johannes Karl; Rustan, Arild Christian & Thoresen, G. Hege [Show all 7 contributors for this article] (2023). Development of three-dimensional primary human myospheres as culture model of skeletal muscle cells for metabolic studies. Frontiers in Bioengineering and Biotechnology. ISSN 2296-4185. 11, p. 1–13. doi: 10.3389/fbioe.2023.1130693. Full text in Research Archive
LaLone, Vernon; Aizenshtadt, Aleksandra; Goertz, John; Skottvoll, Frøydis Sved; Mota, Marco Barbero & You, Junji [Show all 15 contributors for this article] (2023). Quantitative chemometric phenotyping of three-dimensional liver organoids by Raman spectral imaging. Cell Reports Methods. 3(4). doi: 10.1016/j.crmeth.2023.100440. Full text in Research Archive
Brinch, Shoshy Alam; Amundsen-Isaksen, Enya; Espada, Sandra; Hammarström, Clara Louise; Aizenshtadt, Aleksandra & Olsen, Petter Angell [Show all 18 contributors for this article] (2022). The Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models. Cancer Research Communications. ISSN 2767-9764. 2(4), p. 233–245. doi: 10.1158/2767-9764.CRC-22-0027.
Busek, Mathias; Aizenshtadt, Aleksandra; Koch, Timo; Frank, Anna; Delon, Ludivine Sylvie Claude & Amirola Martinez, Mikel [Show all 12 contributors for this article] (2022). Pump-less, recirculating organ-on-a-chip (rOoC) platform . Lab on a Chip. ISSN 1473-0197. p. 345–361. doi: 10.1039/d2lc00919f. Full text in Research Archive
Kogler, Stian; Aizenshtadt, Aleksandra; Harrison, Sean; Skottvoll, Frøydis Sved; Berg, Henriette Engen & Abadpour, Shadab [Show all 14 contributors for this article] (2022). "Organ-in-a-Column" Coupled On-line with Liquid Chromatography-Mass Spectrometry. Analytical Chemistry. ISSN 0003-2700. 94(50), p. 17677–17684. doi: 10.1021/acs.analchem.2c04530. Full text in Research Archive
Busek, Mathias; Aizenshtadt, Aleksandra; Amirola Martinez, Mikel; Delon, Ludivine Sylvie Claude & Krauss, Stefan Johannes Karl (2022). Academic User View: Organ-on-a-Chip Technology. Biosensors. ISSN 2079-6374. 12(2). doi: 10.3390/bios12020126. Full text in Research Archive Show summary
The pleasantness of gentle stroking (CT-targeted touch) varies highly between individuals and studies, indicating that relevant factors may not be accounted for. We propose that the affective value of a touch event is determined by how well its perceived purpose matches the goals of the touch receiver. The perceived purpose or meaning of touch is in turn informed by the sensory characteristics together with the setting, person factors, and the touchee’s expectations. Affective touch is often a sign of affection, intended to soothe or show support. In a typical lab study however, the toucher is a stranger and its purpose is research. The purpose of laboratory touch is nevertheless compatible with the goal of participants, namely to contribute to research. To fully understand how the perception of affective touch emerges, more studies should directly manipulate participants’ beliefs about the purpose of touch.
Skottvoll, Frøydis Sved; Aizenshtadt, Aleksandra; Hansen, Frederik Andre; Amirola Martinez, Mikel; Andersen, Jannike Mørch & Bogen, Inger Lise [Show all 11 contributors for this article] (2022). Direct Electromembrane Extraction-Based Mass Spectrometry: A Tool for Studying Drug Metabolism Properties of Liver Organoids. Analysis & Sensing. ISSN 2629-2742. 2(2). doi: 10.1002/anse.202100051. Full text in Research Archive
Mygland, Line; Mahmuda, Shoshy; Strand, Martin Frank; Olsen, Petter Angell; Aizenshtadt, Aleksandra & Lund, Kaja [Show all 21 contributors for this article] (2021). Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. iScience. ISSN 2589-0042. 24(7). doi: 10.1016/j.isci.2021.102807. Full text in Research Archive
Busek, Mathias; Nøvik, Steffen; Aizenshtadt, Aleksandra; Amirola Martinez, Mikel; Combriat, Thomas Michel Daniel & Grünzner, Stefan [Show all 7 contributors for this article] (2021). Thermoplastic elastomer (Tpe)–poly(methyl methacrylate) (pmma) hybrid devices for active pumping pdms-free organ-on-a-chip systems. Biosensors. ISSN 2079-6374. 11(5). doi: 10.3390/bios11050162. Full text in Research Archive
Skottvoll, Frøydis Sved; Hansen, Frederik; Harrison, Sean; Boger, Ida Caroline Sneis; Mrsa, Ago & Restan, Magnus Saed [Show all 14 contributors for this article] (2021). Electromembrane extraction and mass spectrometry for liver organoid drug metabolism studies. Analytical Chemistry. ISSN 0003-2700. 93, p. 3576–3585. doi: 10.1021/acs.analchem.0c05082. Full text in Research Archive
Abadpour, Shadab; Aizenshtadt, Aleksandra; Olsen, Petter Angell; Shoji, Kayoko; Wilson, Steven Ray Haakon & Krauss, Stefan [Show all 7 contributors for this article] (2020). Pancreas-on-a-Chip Technology for Transplantation Applications. Current Diabetes Reports. ISSN 1534-4827. 20. doi: 10.1007/s11892-020-01357-1. Full text in Research Archive
Kogler, Stian; Harrison, Sean; Aizenshtadt, Aleksandra; Skottvoll, Frøydis Sved; Abadpour, Shadab & Krauss, Stefan [Show all 10 contributors for this article] (2020). “Organoid-in-a-column” coupled on-line with liquid chromatography-mass spectrometry. bioRxiv. ISSN 2692-8205. doi: 10.1101/2020.09.08.282756.
Waaler, Jo; Mygland, Line; Tveita, Anders Aune; Strand, Martin Frank; Solberg, Nina & Olsen, Petter Angell [Show all 19 contributors for this article] (2020). Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Communications Biology. ISSN 2399-3642. 3. doi: 10.1038/s42003-020-0916-2. Full text in Research Archive

View all works in Cristin

Kogler, Stian; Aizenshtadt, Aleksandra; Harrison, Sean Philip; Sullivan, Gareth John; Lundanes, Elsa & Bogen, Inger Lise [Show all 9 contributors for this article] (2023). Organ-in-a-column – automated on-line incubation, sampling, and LC-MS analysis for measurement of drug metabolites.
Røberg-Larsen, Hanne; Kømurcu, Kristina Sæterdal; Kogler, Stian; Olsen, Christine; Skottvoll, Frøydis Sved & Aizenshtadt, Aleksandra [Show all 8 contributors for this article] (2023). Organoids, Organ-on-a-chip and Mass Spectrometry.
Skottvoll, Frøydis Sved; Aizenshtadt, Aleksandra; Harrison, Sean; Krauss, Stefan Johannes Karl; Sullivan, Gareth & Bogen, Inger Lise [Show all 9 contributors for this article] (2022). Organ-in-a-column - On-line incubation and LC-MS-analysis for drug metabolism studies.
Wilson, Steven Ray Haakon; Røberg-Larsen, Hanne; Krauss, Stefan Johannes Karl & Aizenshtadt, Aleksandra (2022). Organ-in-a-column - An automated on-line incubation and analysis system for drug metabolism studies.
Kømurcu, Kristina Sæterdal; Aizenshtadt, Aleksandra; Thorne, James L.; Krauss, Stefan Johannes Karl; Wilson, Steven Ray Haakon & Røberg-Larsen, Hanne (2022). Oxysterols are secreted from Non-Alcoholic Fatty Liver Disease (NAFLD) induced organoids.
Kømurcu, Kristina Sæterdal; Aizenshtadt, Aleksandra; Thorne, James L; Krauss, Stefan Johannes Karl; Wilson, Steven Ray Haakon & Røberg-Larsen, Hanne (2022). Measuring oxysterols secreted from liver organoids by LC-MS for the understanding of Non-alcoholic fatty liver disease .
Kømurcu, Kristina Sæterdal; Aizenshtadt, Aleksandra; Thorne, James L; Krauss, Stefan Johannes Karl; Wilson, Steven Ray Haakon & Røberg-Larsen, Hanne (2022). Oxysterols are secreted from Non-alcoholic Fatty Liver disease induced organoids.
Kømurcu, Kristina Sæterdal; Aizenshtadt, Aleksandra; Thorne, James L; Krauss, Stefan Johannes Karl; Wilson, Steven Ray Haakon & Røberg-Larsen, Hanne (2022). Measuring oxysterols secreted from liver organoids by LC-MS for the understanding of Non-alcoholic fatty liver disease.
Kømurcu, Kristina Sæterdal; Aizenshtadt, Aleksandra; Thorne, James L; Wilson, Steven Ray Haakon & Røberg-Larsen, Hanne (2022). Measuring oxysterols using LC-MS for the understanding of non alcoholic fatty liver disease (NAFLD).
Nordli, Henriette; Aizenshtadt, Aleksandra; Krauss, Stefan Johannes Karl; Wilson, Steven Ray Haakon & Røberg-Larsen, Hanne (2021). Oxysterols secreted from a Non-Alcoholic Fatty Liver Disease (NAFLD) induced liver organoids.

View all works in Cristin

Published June 28, 2019 3:09 PM - Last modified Aug. 3, 2023 12:56 PM