https://orcid.org/0000-0002-1220-1745
My main interest is the study of the communication between cells and organs through endocrine or neural pathways.
I am currently part of the SmartSense project with the aim of understanding how sleep deprivation alters adipose tissue homeostasis.
I did a PhD in Clermont-Ferrand, France, working on the role of a post-translational modification called SUMOylation in the differentiation of adrenocortical cells.
Dufour, D. Timing of food intake affects energy expenditure. Nat Rev Endocrinol (2023)
Dufour, D., Dumontet, T., Sahut-Barnola, I. et al. Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation in mice. Nat Commun 13, 7858 (2022).
Wilmouth, J., Olabe, J., Garcia-Garcia, D., Lucas C., Guiton, R., Roucher-Boulez, F, Dufour, D., et al. (2022) Sexually dimorphic activation of innate antitumour immunity prevents adrenocortical carcinoma development. Sci. Adv. 8, eadd0422.
Sahut-Barnola, I., Lefrancois-Martinez, A.-M., Dufour, D., Botto, J.-M., Kamilaris, C., Faucz, F.R., Stratakis, C.A., Val, P., and Martinez, A. (2022). Steroidogenic factor-1 lineage origin of skin lesions in Carney complex syndrome. Journal of Investigative Dermatology.
Djari, C., Sahut-Barnola, I., Septier, A., Plotton, I., Montanier, N., Dufour, D., Levasseur, A., Wilmouth, J., Pointud, J.-C., Faucz, F.R., et al. (2021). Protein kinase A drives paracrine crisis and WNT4-dependent testis tumor in Carney complex. Journal of Clinical Investigation 131, e146910.
Dumontet, T., Sahut-Barnola, I.,Dufour, D.., Lefrançois-Martinez, A., Berthon, A., Montanier, N., Ragazzon, B., Djari, C., Pointud, J., Roucher-Boulez, F., et al. (2019). Hormonal and spatial control of SUMOylation in the human and mouse adrenal cortex. FASEB j. 33, 10218–10230.
Ishaq*, A., Dufour*, D., Cameron, K., von Zglinicki, T., and Saretzki, G. (2018). Metabolic memory of dietary restriction ameliorates DNA damage and adipocyte size in mouse visceral adipose tissue. Experimental Gerontology 113, 228–236. (* equal contribution)