Sophie Emilie Bresson

Doctoral Research Fellow - Xenobiotics and metabolism
Image of Sophie Emilie Bresson
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Email s.e.bresson@medisin.uio.no
Mobile phone +47 94184944
Room 2265b
Username
Visiting address Sognsvannsveien 9 Domus Medica 0372 Oslo
Postal address Postboks 1112, Blindern 0317 Oslo
Other affiliations Faculty of Medicine (Student)

Academic interests

Current work focuses on xenobiotic receptors and their role in muscle atrophy, as well as Persistent Organic Pollutants and pancreatic beta-cells.

Courses taught

Background

M.Sc. and B.Sc. in Molecular Biomedicine from University of Copenhagen, Denmark.

Previous occupation as Assistant Lecturer, at University of Copenhagen. Teaching Cell Biology and Medical Genetics.

Research background in diabetes, pancreatic beta-cells, protein folding, Endoplasmic reticulum function, protein degradation and molecular inflammation

Positions held

  • PhD student (current)

 

https://orcid.org/0000-0002-8623-2237

 

 

Selected publications

  • Bresson SE and Ruzzin J. Persistent Organic Pollutants Disrupt the Oxidant/Antioxidant Balance of Ins-1e Pancreatic Β-Cells Causing Their Physiological Dysfunctions. Environment Int. 2024 190 (2024/08/01/ 2024): 108821. (Link)

  • Amini SE, Bresson SE, Ruzzin J. Mice lacking intestinal Nr1i2 have normal intestinal homeostasis under steady-state conditions and are not hypersensitive to inflammation under lipopolysaccharide treatment. FASEB J. 2023;37(8):e23117. doi:10.1096/fj.202301126 (Link)
  • Hoefner, C.; Bryde, T.H.; Pihl, C.; Tiedemann, S.N.; Bresson, S.E.; Hotiana, H.A.; Khilji, M.S.; Santos, T.D.; Puglia, M.; Pisano, P.; Majewska, M.; Durzynska, J.; Klindt, K.; Klusek, J.; Perone, M.J.; Bucki, R.; Hägglund, P.M.; Gourdon, P.E.; Gotfryd, K.; Urbaniak, E.; Borowiak, M.; Wierer, M.; MacDonald, P.E.; Mandrup-Poulsen, T.; Marzec, M.T. FK506-Binding Protein 2 Participates in Proinsulin Folding. Biomolecules 2023, 13, 152. https://doi.org/10.3390/biom13010152(Link)
  • Bresson, Sophie E., Scott Isom, Elizabeth T. Jensen, Sandra Huber, Youssef Oulhote, Joseph Rigdon, James Lovato, Angela D. Liese, Catherine Pihoker, Dana Dabelea, Shelley Ehrlich, and Jérôme Ruzzin. "Associations between Persistent Organic Pollutants and Type 1 Diabetes in Youth." Environ Int. 2022 Mar 16;163:107175. doi: 10.1016/j.envint.2022.107175. Epub ahead of print. PMID: 35303528. (Link).
  • Argon Y, Bresson SE, Marzec MT, Grimberg A. "Glucose-Regulated Protein 94 (GRP94): A Novel Regulator of Insulin-Like Growth Factor Production." Cells. 2020 Aug 6;9(8):1844. doi: 10.3390/cells9081844. PMID: 32781621; PMCID: PMC7465916.(Link)
  • Khilji MS, Bresson SE, Verstappen D, Pihl C, Andersen PAK, Agergaard JB, Dahlby T, Bryde TH, Klindt K, Nielsen CK, Walentinsson A, Zivkovic D, Bousquet MP, Tyrberg B, Richardson SJ, Morgan NG, Mandrup-Poulsen T, Marzec MT. "The inducible β5i proteasome subunit contributes to proinsulin degradation in GRP94-deficient β-cells and is overexpressed in type 2 diabetes pancreatic islets." Am J Physiol Endocrinol Metab. 2020 Jun 1;318(6):E892-E900. doi: 10.1152/ajpendo.00372.2019. Epub 2020 Apr 7. PMID: 32255680.(Link)
  • Khilji MS, Verstappen D, Dahlby T, Burstein Prause MC, Pihl C, Bresson SE, Bryde TH, Keller Andersen PA, Klindt K, Zivkovic D, Bousquet-Dubouch MP, Tyrberg B, Mandrup-Poulsen T, Marzec MT. "The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β." PLoS One. 2020 Feb 13;15(2):e0222432. doi: 10.1371/journal.pone.0222432. PMID: 32053590; PMCID: PMC7018053.(Link)
  • Ghiasi SM, Dahlby T, Hede Andersen C, Haataja L, Petersen S, Omar-Hmeadi M, Yang M, Pihl C, Bresson SE, Khilji MS, Klindt K, Cheta O, Perone MJ, Tyrberg B, Prats C, Barg S, Tengholm A, Arvan P, Mandrup-Poulsen T, Marzec MT. "Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling." Diabetes. 2019 Apr;68(4):747-760. doi: 10.2337/db18-0671. Epub 2019 Jan 22. PMID: 30670477; PMCID: PMC6425875.(Link)
Published Mar. 12, 2021 1:23 PM - Last modified June 17, 2024 9:56 AM

Research groups