Immunobiology

The immune system protects us against infection and cancer but may also overreact and cause autoimmune disease. Knowledge of molecular mechanisms regulating immune cell activation and control is needed to understand how autoimmune diseases may be prevented or treated.

The immunology group combines proteomics with molecular and cellular biology to investigate the regulation of innate and adaptive immunity, and pathogenic mechanisms involved in autoimmune disease and cancer.

We study

  • Molecular and cellular control mechanisms involved in selective activation and regulation of T-cells and natural killer cells in health and disease (Spurkland, DissenChristophersen)
  • The regulation of immune responses in multiple sclerosis, with focus on B-cell response in blood and cerebrospinal fluid (Lossius, Spurkland)
  • The role of pattern-recognizing receptors and genomic variations in autoimmune arthritis (Daws, Christophersen)

Publications

Principal investigators

 

Tags: Immunology, immunoreceptors, signaling, autoimmune disease, Cancer, cancer immunotherapy
Published June 9, 2023 1:25 PM - Last modified Jan. 24, 2024 3:05 PM