Selected publications

Selected publications last 5 years:

1: Szu J, Parpura V, Amiry-Moghaddam M, Smith AJ. Editorial: Mechanisms and
consequences of Aquaporin-4 redistribution in neurological disease. Front Cell
Neurosci. 2023 Feb 1;17:1143352. doi: 10.3389/fncel.2023.1143352. PMID:
36816853; PMCID: PMC9930891.

2: Skauli N, Savchenko E, Ottersen OP, Roybon L, Amiry-Moghaddam M. Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes. Front Cell Neurosci. 2022 Apr 20;16:878154. doi: 10.3389/fncel.2022.878154. PMID: 35518645; PMCID: PMC9067306.

3: Banitalebi S, Skauli N, Geiseler S, Ottersen OP, Amiry-Moghaddam M.
Disassembly and Mislocalization of AQP4 in Incipient Scar Formation after
Experimental Stroke. Int J Mol Sci. 2022 Jan 20;23(3):1117. doi:
10.3390/ijms23031117. PMID: 35163040; PMCID: PMC8835637.

4: Dias DO, Kalkitsas J, Kelahmetoglu Y, Estrada CP, Tatarishvili J, Holl D,
Jansson L, Banitalebi S, Amiry-Moghaddam M, Ernst A, Huttner HB, Kokaia Z,
Lindvall O, Brundin L, Frisén J, Göritz C. Pericyte-derived fibrotic scarring is
conserved across diverse central nervous system lesions. Nat Commun. 2021 Sep
17;12(1):5501. doi: 10.1038/s41467-021-25585-5. PMID: 34535655; PMCID:
PMC8448846.

5: Rao SB, Skauli N, Jovanovic N, Katoozi S, Frigeri A, Froehner SC, Adams ME,
Ottersen OP, Amiry-Moghaddam M. Orchestrating aquaporin-4 and connexin-43
expression in brain: Differential roles of α1- and β1-syntrophin. Biochim
Biophys Acta Biomembr. 2021 Aug 1;1863(8):183616. doi:
10.1016/j.bbamem.2021.183616. Epub 2021 Apr 16. PMID: 33872576.

6: Prydz A, Stahl K, Zahl S, Skauli N, Skare Ø, Ottersen OP, Amiry-Moghaddam M.
Pro-Inflammatory Role of AQP4 in Mice Subjected to Intrastriatal Injections of
the Parkinsonogenic Toxin MPP. Cells. 2020 Nov 5;9(11):2418. doi:
10.3390/cells9112418. PMID: 33167342; PMCID: PMC7694382.

7: Katoozi S, Rao SB, Skauli N, Froehner SC, Ottersen OP, Adams ME, Amiry-
Moghaddam M. Functional specialization of retinal Müller cell endfeet depends on
an interplay between two syntrophin isoforms. Mol Brain. 2020 Mar 16;13(1):40.
doi: 10.1186/s13041-020-00581-w. PMID: 32178707; PMCID: PMC7074989.

8: Palazzo C, Abbrescia P, Valente O, Nicchia GP, Banitalebi S, Amiry-Moghaddam
M, Trojano M, Frigeri A. Tissue Distribution of the Readthrough Isoform of AQP4
Reveals a Dual Role of AQP4ex Limited to CNS. Int J Mol Sci. 2020 Feb
24;21(4):1531. doi: 10.3390/ijms21041531. PMID: 32102323; PMCID: PMC7073200.

9: Hoddevik EH, Rao SB, Zahl S, Boldt HB, Ottersen OP, Amiry-Moghaddam M.
Organisation of extracellular matrix proteins laminin and agrin in pericapillary
basal laminae in mouse brain. Brain Struct Funct. 2020 Mar;225(2):805-816. doi:
10.1007/s00429-020-02036-3. Epub 2020 Feb 18. PMID: 32072250; PMCID: PMC7046580.

10: Katoozi S, Skauli N, Zahl S, Deshpande T, Ezan P, Palazzo C, Steinhäuser C,
Frigeri A, Cohen-Salmon M, Ottersen OP, Amiry-Moghaddam M. Uncoupling of the
Astrocyte Syncytium Differentially Affects AQP4 Isoforms. Cells. 2020 Feb
7;9(2):382. doi: 10.3390/cells9020382. PMID: 32046059; PMCID: PMC7072498.

11: Rao SB, Katoozi S, Skauli N, Froehner SC, Ottersen OP, Adams ME, Amiry-
Moghaddam M. Targeted deletion of β1-syntrophin causes a loss of K_ir
4.1 from Müller cell endfeet in mouse retina. Glia. 2019 Jun;67(6):1138-1149.
doi: 10.1002/glia.23600. Epub 2019 Feb 25. PMID: 30803043; PMCID: PMC6462228.

12: Stahl K, Rahmani S, Prydz A, Skauli N, MacAulay N, Mylonakou MN, Torp R,
Skare Ø, Berg T, Leergaard TB, Paulsen RE, Ottersen OP, Amiry-Moghaddam M.
Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of
Parkinson's disease. PLoS One. 2018 Mar 22;13(3):e0194896. doi:
10.1371/journal.pone.0194896. PMID: 29566083; PMCID: PMC5864064.

Selected publications before 2018:

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• Hoddevik EH, Khan FH, Rahmani S, Ottersen OP, Boldt HB, Amiry-Moghaddam M. Factors determining the density of AQP4 water channel molecules at the brain-blood interface. Brain Struct Funct. 2017 May;222(4):1753-1766. doi: 10.1007/s00429-016-1305-y. Epub 2016 Sep 15. PMID: 27629271; PMCID: PMC5406442.
• Bjertness E, Htay TT, Maung NS, Soe ZW, Aye SS, Ottersen OP, Liabsuetrakul T, Grøttum P, Hovland M, Amiry-Moghaddam M. E-learning resources in Myanmar. Lancet. 2016 Dec 17;388(10063):2990-2991. doi: 10.1016/S0140-6736(16)32520-X. PMID: 27998528.
• Ricanek P, Lunde LK, Frye SA, Støen M, Nygård S, Morth JP, Rydning A, Vatn MH, Amiry-Moghaddam M, Tønjum T. Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease. Clin Exp Gastroenterol. 2015 Jan 9;8:49-67. doi: 10.2147/CEG.S70119. PMID: 25624769; PMCID: PMC4296881.
• Camassa LMA, Lunde LK, Hoddevik EH, Stensland M, Boldt HB, De Souza GA, Ottersen OP, Amiry-Moghaddam M. Mechanisms underlying AQP4 accumulation in astrocyte endfeet. Glia. 2015 Nov;63(11):2073-2091. doi: 10.1002/glia.22878. Epub 2015 Jun 29. PMID: 26119521.
• Amiry-Moghaddam M, Ottersen OP. Immunogold cytochemistry in neuroscience. Nat Neurosci. 2013 Jul;16(7):798-804. doi: 10.1038/nn.3418. Epub 2013 Jun 25. PMID: 23799472.
• Alvestad S, Hammer J, Hoddevik EH, Skare Ø, Sonnewald U, Amiry-Moghaddam M, Ottersen OP. Mislocalization of AQP4 precedes chronic seizures in the kainate model of temporal lobe epilepsy. Epilepsy Res. 2013 Jul;105(1-2):30-41. doi: 10.1016/j.eplepsyres.2013.01.006. Epub 2013 Jan 26. PMID: 23357720.
• Promeneur D, Lunde LK, Amiry-Moghaddam M, Agre P. Protective role of brain water channel AQP4 in murine cerebral malaria. Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):1035-40. doi: 10.1073/pnas.1220566110. Epub 2012 Dec 31. PMID: 23277579; PMCID: PMC3549120.
• Benfenati V, Caprini M, Dovizio M, Mylonakou MN, Ferroni S, Ottersen OP, Amiry-Moghaddam M. An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2563-8
• Nuntagij P, Oddo S, LaFerla FM, Kotchabhakdi N, Ottersen OP, Torp R. Amyloid deposits show complexity and intimate spatial relationship with dendrosomatic plasma membranes: an electron microscopic 3D reconstruction analysis in 3xTg-AD mice and aged canines. J Alzheimers Dis. 2009;16(2):315-23.
• Mylonakou MN, Petersen PH, Zelenin S, Rojek AM, Rinvik E, Nielsen S, Ottersen OP, Amiry-Moghaddam M*:AQP9 is expressed in the dopaminergic neurons in the Substantia Nigra: Quantitative analysis of AQP9 mRNA in the mouse. Journal of Neuroscience Research, 2009 May 1;87(6):1310-22.
• Frydenlund DS, Bhardwaj A, Otsuka T, Mylonakou MN, Yasumura T, Davidson KG, Zeynalov E, Skare O, Laake P, Haug FM, Rash JE, Agre P, Ottersen OP, Amiry-Moghaddam M*: Temporary loss of perivascular aquaporin-4 in neocortex after transient middle cerebral artery occlusion in mice. Proc Natl Acad Sci U S A. 2006 Sep 5;103(36):13532-6.
• Amiry-Moghaddam M*, Lindland H, Zelenin S, Roberg BA, Gundersen BB, Petersen P, Rinvik E, Torgner IA, Ottersen OP: Brain mitochondria contain aquaporin water channels: evidence for the expression of a short AQP9 isoform in the inner mitochondrial membrane. FASEB J. 2005 Sep;19(11):1459-67.
• Eid T, Lee TS, Thomas MJ, Amiry-Moghaddam M, Bjornsen LP, Spencer DD, Agre P, Ottersen OP, de Lanerolle NC: Loss of perivascular aquaporin 4 may underlie deficient water and K+ homeostasis in the human epileptogenic hippocampus. Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1193-8.
• Amiry-Moghaddam M, Xue R,Haug FM, Neely JD, Bardwaj A, Agre P, Adams ME, Froehner SC, Mori S, Ottersen OP. Alpha syntrophin deletion removes the perivascular but nor the endothelial pool of aquaporin-4 at the blood-brain-barrier and delays the development of brain edema in an experimental model of acute hyponatremia. FASEB J 2004 Mar; 18 (3):542-4 2004.
• Amiry-Moghaddam M and Ottersen OP. Molecular Basis for Water transport in Brain. Nature Reviews Neuroscience (2003) Dec 4:991-1001.
• Amiry-Moghaddam M, Williamson A, Palomba M, Eid T, de Lanerolle NC, Nagelhus EA, Adams ME, Froehner SC, Agre P, Ottersen OP. Delayed potassium clearance and increased seizure severity I mice lacking alpha-syntrophin. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13615-20.
• Amiry-Moghaddam M, Otsuka T, Hurn PD, Traystman RJ, Haug FM, Froehner SC, Adams ME, Neely JD, Agre P, Ottersen OP*, Bhardwaj A. An alpha-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):2106-11.