Anne-Marie Aas

• Olsen, Sissel Urke; TAZMINI, KIARASH; Aas, Anne-Marie; Ranhoff, Anette Hylen; Pripp, Are Hugo & Hesseberg, Karin [Show all 8 contributors for this article] (2024). The incidence and mortality of refeeding syndrome in older hospitalized patients, based on three different diagnostic criteria: A longitudinal study. Clinical Nutrition ESPEN. ISSN 2405-4577. 61, p. 101–107. doi: 10.1016/j.clnesp.2024.03.006.
• Zerouga, Insaf; Valeur, Jørgen; Sommer, Christine; Småstuen, Milada Cvancarova; Medhus, Asle Wilhelm & Lund, Charlotte [Show all 22 contributors for this article] (2024). Dietary intake and nutritional status in patients with newly diagnosed inflammatory bowel disease: insights from the IBSEN III study. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. p. 1–9. doi: 10.1080/00365521.2024.2313056. Show summary

  Background: Dietary recommendations in inflammatory bowel disease (IBD) are inconclusive, and patients may follow restrictive diets with increased risk of malnutrition. The aim of this study was to compare dietary intakes and nutritional status in men and women with newly diagnosed IBD with a general population sample, and to investigate whether intakes were in line with the Nordic Nutrition Recommendations. Methods: This was a cross-sectional study including adults≥ 40 years with IBD from the Inflammatory Bowel Disease in South-Eastern Norway (IBSEN) III cohort study. A validated food frequency questionnaire (FFQ) was used in dietary data collection, and a sample from the seventh survey of the Tromsø Study was included as a comparison group. Results: A total of 227 men and women with IBD were included. IBD patients had higher intake of grain products, sweetened beverages, energy, fat and polyunsaturated fat (PUFA), but lower intake of dairy products, alcohol and iodine compared to adults from the comparison sample (p < 0.01). Intakes of saturated fat and carbohydrates in both genders, and vitamin D in women were not within recommended levels. Anemia and hypoalbuminemia were more prevalent in IBD patients than in the comparison sample. Conclusions: Dietary intakes in newly diagnosed IBD patients were mostly in line with Nordic Nutrition Recommendations. Higher proportion of IBD patients exceeded recommended allowances of fat and added sugar than the comparison sample. Insufficient micronutrient intake, anemia and hypoalbuminemia are present challenges in IBD patients that require monitoring.

• Fredriksen, Petra Elizabeth Chapman; Aas, Anne-Marie; Bjerkan, Kirsti & Garnweidner-Holme, Lisa (2023). Experiences of follow-up and dietary guidance among young adults diagnosed with type 1 diabetes as children: a qualitative study. Norsk tidsskrift for ernæring (NTFE). ISSN 1503-5034. 21(3), p. 2–10. doi: 10.18261/ntfe.21.3.2.
• Birkeland, Eline; Gharagozlian, Sedeghe; Valeur, Jørgen & Aas, Anne-Marie (2023). Short-chain fatty acids as a link between diet and cardiometabolic risk: a narrative review. Lipids in Health and Disease. ISSN 1476-511X. 22(1). doi: 10.1186/s12944-023-01803-5. Full text in Research Archive
• Massara, Paraskevi; Zurbau, Andreea; Glenn, Andrea J.; Chiavaroli, Laura; Khan, Tauseef A. & Viguiliouk, Effie [Show all 20 contributors for this article] (2022). Nordic dietary patterns and cardiometabolic outcomes: a systematic review and meta-analysis of prospective cohort studies and randomised controlled trials. Diabetologia. ISSN 0012-186X. 65, p. 2011–2031. doi: 10.1007/s00125-022-05760-z. Full text in Research Archive
• Rishaug, Tina; Henriksen, André; Aas, Anne-Marie; Hartvigsen, Gunnar; Birkeland, Kåre Inge & Årsand, Eirik (2022). Designing an e-Health Program for Lifestyle Changes in Diabetes Care A Qualitative Pre-Study in Norway. In Henriksen, André; Gabarron, Elia & Vimarlund, Vivian (Ed.), Proceedings of the 18th Scandinavian Conference on Health Informatics. Linköping Electronic Conference Proceedings. ISSN 978-91-7929-344-4. doi: 10.3384/ecp187013. Full text in Research Archive
• Giertsen, Elin; Svendsen, Gunnar & Aas, Anne-Marie (2021). Kostråd til den kariesaktive pasienten – er det viktigst å begrense sukkermengden eller inntaksfrekvensen? Den norske tannlegeforenings tidende. ISSN 0029-2303. 131(8), p. 724–727.
• Giertsen, Elin; Bergesen, Guri Høgenæs; Bakken, Turid Birkeland & Aas, Anne-Marie (2021). Alternative søtningsmidler: Egenskaper, bruksområder, sikkerhetsaspekter og helseeffekter – Del 2: Intense søtstoff. Den norske tannlegeforenings tidende. ISSN 0029-2303. 131(8), p. 702–714.
• Giertsen, Elin; Bakken, Torunn Birkeland; Bergesen, Guri Høgenæs & Aas, Anne-Marie (2021). Alternative søtningsmidler: Egenskaper, bruksområder, sikkerhetsaspekter og helseeffekter – Del 1: Sukkeralkoholene. . Den norske tannlegeforenings tidende. ISSN 0029-2303. 131(8), p. 690–700.
• Birkeland, Eline; Gharagozlian, Sedegheh; Birkeland, Kåre I.; Holm, Oda Kristine S.; Thorsby, Per Medbøe & Aas, Anne-Marie (2021). Effect of inulin-type fructans on appetite in patients with type 2 diabetes: A randomised controlled crossover trial. Journal of Nutritional Science (JNS). ISSN 2048-6790. 10, p. 1–11. doi: 10.1017/jns.2021.70. Full text in Research Archive
• Birkeland, Eline; Gharagozlian, Sedegheh; Gulseth, Hanne L.; Birkeland, Kåre I.; Hartmann, Bolette & Holst, Jens J. [Show all 8 contributors for this article] (2021). Effects of prebiotics on postprandial GLP-1, GLP-2 and glucose regulation in patients with type 2 diabetes: A randomised, double-blind, placebo-controlled crossover trial. Diabetic Medicine. ISSN 0742-3071. 38(10), p. 1–10. doi: 10.1111/dme.14657. Full text in Research Archive
• Olsen, Sissel Urke; Hesseberg, Karin; Aas, Anne-Marie; Pripp, Are Hugo; Ranhoff, Anette Hylen & Bye, Asta (2021). A comparison of two different refeeding protocols and its effect on hand grip strength and refeeding syndrome: a randomized controlled clinical trial. European Geriatric Medicine. ISSN 1878-7649. doi: 10.1007/s41999-021-00520-5. Show summary

  Aim Does a more assertive compared to a cautious initial refeeding protocol improve patient handgrip strength? Findings In this randomized clinical trial of 85 older adults whom received two different refeeding protocols, with tight control of electrolytes, no significant difference in in by handgrip strength was found (p = 0.78). Message A more assertive refeeding protocol providing 20 kcal/kg/day did not improve hand grip strength nutritional status at 3 months compared with a cautious refeeding protocol (10 kcal/kg/day), neither did it show a higher incidence of mortality.

• Olsen, Sissel Urke; Hesseberg, Karin; Aas, Anne-Marie; Ranhoff, Anette Hylen & Bye, Asta (2021). Refeeding syndrome occurs among older adults regardless of refeeding rates: A systematic review. Nutrition Research. ISSN 0271-5317. 91, p. 1–12. doi: 10.1016/j.nutres.2021.05.004. Show summary

  Abstract Refeeding syndrome is a life-threatening clinical disorder that can occur when treating malnutrition. The aim was to examine the current knowledge of refeeding syndrome in patients ≥ 65 + years with special focus on the incidence of hypophosphatemia (HP) in relation to refeeding rate (kcal/kg/day), number of days until the lowest level of phosphate occurs (day of nadir), refeeding rates and adverse events, and death. Specifically, we hypothesized that higher energy provision would cause a higher incidence of HP. A search was conducted in the available databases. Two cohort studies, 1 case control, and a total of 12 case series/case reports, which accounted for 19 individual patient cases, were eligible. The incidence of HP (<0.5 mmol/L) was 15% and 25% in the 2 cohort studies and 4% in the case control study. The mean day of nadir was between days 2 and 3 in the cohort studies, day 11 in the case control study, and day 3 in the cases series/case reports. Importantly, a rapid drop in phosphate occurred receiving both 30 kcal/kg/day and 8 to 10 kcal/kg/day. The cohort studies reported high death rates—26% and 23%—using both 10 and 20 kcal/kg/day, respectively. Adverse events were noted in most all case series/case reports. Clinicians should be aware that HP may occur in up to 25% of older hospitalized adults, and importantly, it occurs even when refeeding cautiously. Hence, electrolytes should be closely monitored, especially between days 2 and 4, which is when the day of nadir occurs most frequently.

• Pfeiffer, Andreas F. H.; Pedersen, Eva; Schwab, Ursula; Risérus, Ulf; Aas, Anne-Marie & Uusitupa, Matti [Show all 14 contributors for this article] (2020). The effects of different quantities and qualities of protein intake in people with diabetes mellitus. Nutrients. ISSN 2072-6643. 12(2), p. 1–12. doi: 10.3390/nu12020365.
• Augustin, Livia S.A.; Aas, Anne-Marie; Astrup, Arnie; Atkinson, Fiona S.; Baer-Sinnott, Sara & Barclay, Alan W. [Show all 29 contributors for this article] (2020). Dietary fibre consensus from the international carbohydrate quality consortium (Icqc). Nutrients. ISSN 2072-6643. 12:2553(9), p. 1–11. doi: 10.3390/nu12092553. Full text in Research Archive
• Birkeland, Eline; Gharagozlian, Sedegheh; Birkeland, Kåre I.; Valeur, Jørgen; Måge, Ingrid & Rud, Ida [Show all 7 contributors for this article] (2020). Prebiotic effect of inulin-type fructans on faecal microbiota and short-chain fatty acids in type 2 diabetes: a randomised controlled trial. European Journal of Nutrition. ISSN 1436-6207. 59, p. 3325–3338. doi: 10.1007/s00394-020-02282-5. Full text in Research Archive Show summary

  Purpose Compared to a healthy population, the gut microbiota in type 2 diabetes presents with several unfavourable features that may impair glucose regulation. The aim of this study was to evaluate the prebiotic efect of inulin-type fructans on the faecal microbiota and short-chain fatty acids (SCFA) in patients with type 2 diabetes. Methods The study was a placebo controlled crossover study, where 25 patients (15 men) aged 41–71 years consumed 16 g of inulin-type fructans (a mixture of oligofructose and inulin) and 16-g placebo (maltodextrin) for 6 weeks in randomised order. A 4-week washout separated the 6 weeks treatments. The faecal microbiota was analysed by high-throughput 16S rRNA amplicon sequencing and SCFA in faeces were analysed using vacuum distillation followed by gas chromatography. Results Treatment with inulin-type fructans induced moderate changes in the faecal microbiota composition (1.5%, p=0.045). A bifdogenic efect was most prominent, with highest positive efect on operational taxonomic units (OTUs) of Bifdobacterium adolescentis, followed by OTUs of Bacteroides. Signifcantly higher faecal concentrations of total SCFA, acetic acid and propionic acid were detected after prebiotic consumption compared to placebo. The prebiotic fbre had no efects on the concentration of butyric acid or on the overall microbial diversity. Conclusion Six weeks supplementation with inulin-type fructans had a signifcant bifdogenic efect and induced increased concentrations of faecal SCFA, without changing faecal microbial diversity. Our fndings suggest a moderate potential of inulin-type fructans to improve gut microbiota composition and to increase microbial fermentation in type 2 diabetes. Trial registration The trial is registered at clinicaltrials.gov (NCT02569684).

• Hanvold, Susanna; Vinknes, Kathrine; Løken, Elin Bjørge; Hjartåker, Anette; Klungsøyr, Ole & Birkeland, Eline [Show all 10 contributors for this article] (2019). Does Lifestyle Intervention After Gastric Bypass Surgery Prevent Weight Regain? A Randomized Clinical Trial. Obesity Surgery. ISSN 0960-8923. 29(11), p. 3419–3431. doi: 10.1007/s11695-019-04109-7. Full text in Research Archive
• Korsmo-Haugen, Henny-Kristine; Brurberg, Kjetil Gundro; Mann, Jim I & Aas, Anne-Marie (2019). Carbohydrate quantity in the dietary management of type 2 diabetes: A systematic review and meta-analysis. Diabetes, obesity and metabolism. ISSN 1462-8902. 21(1), p. 15–27. doi: 10.1111/dom.13499. Full text in Research Archive
• Hanvold, Susanna; Vinknes, Kathrine; Bastani, Nasser Ezzatkhah; Turner, Cheryl; Løken, Elin Bjørge & Mala, Tom [Show all 8 contributors for this article] (2017). Plasma amino acids, adiposity, and weight change after gastric bypass surgery: are amino acids associated with weight regain? European Journal of Nutrition. ISSN 1436-6207. p. 1–9. doi: 10.1007/s00394-017-1533-9.
• Aaseth, Eirik; Fagerland, Morten; Aas, Anne-Marie; Hewitt, Stephen I; Risstad, Hanne & Kristinsson, Jon Adalsteinn [Show all 9 contributors for this article] (2015). Vitamin concentrations 5 years after gastric bypass. European Journal of Clinical Nutrition. ISSN 0954-3007. 69, p. 1249–1255. doi: 10.1038/ejcn.2015.82. Show summary

  Background/Objectives: Few studies have investigated the effects of bariatric surgery on vitamin status in the long term. We examined changes in vitamin status up to 5 years after Roux-en-Y gastric bypass surgery. Subjects/Methods: Using a retrospectively maintained database of patients undergoing weight loss surgery, we identified all patients operated with Roux-en-Y gastric bypass at our tertiary care hospital during July 2004–May 2008. Data on vitamin concentrations and patient-reported intake of dietary supplements were collected up to July 2012. Linear mixed models were used to estimate changes in vitamin concentrations during follow-up, adjusting for age and sex. All patients were recommended daily oral multivitamin, calcium/vitamin D and iron supplements and 3-monthly intramuscular B-12 after surgery. Results: Out of the 443 patients operated with gastric bypass, we included 441 (99.5%) patients with one or more measurements of vitamin concentrations (75.1% women; mean age 41.5 years, mean body mass index 46.1 kg/m2 at baseline). At 5 years after surgery, the patients' estimated mean vitamin concentrations were either significantly higher (vitamin B-6, folic acid, vitamin B-12, vitamin C and vitamin A) or not significantly different (thiamine, 25-hydroxyvitamin D and lipid-adjusted vitamin E) compared with before surgery. Use of multivitamin, calcium/vitamin D and vitamin B-12 supplements was reported by 1–9% of patients before surgery, 79–84% of patients at 1 year and 52–83% of patients 5 years after surgery. Conclusions: In patients who underwent gastric bypass surgery, estimated vitamin concentrations were either significantly increased or unchanged up to 5 years after surgery.

• Hanvold, Susanna; Løken, Elin Bjørge; Paus, Sofie Flottorp; de Brisis, Eva Rustad; Bjerkan, Kirsti & Refsum, Helga [Show all 7 contributors for this article] (2015). Great Health Benefits But No Change in Employment or Psychopharmaceutical Drug Use 2 Years After Roux-en-Y Gastric Bypass. Obesity Surgery. ISSN 0960-8923. 25(9), p. 1672–1679. doi: 10.1007/s11695-015-1583-0. Show summary

  Abstract Background The aim was to examine health benefits and lifestyle factors after Roux-en-Y gastric bypass (RYGB). Methods Patients (n=165) were investigated 2 years after RYGB in relation to psychopharmaceutical drugs, employment status, type 2 diabetes mellitus (T2DM), hypertension, metabolic syndrome (MetS), body weight, physical activity (PA), and energy intake. Results Excess weight loss (EWL) was 71.4±20.6 %. Prevalence of T2DM, hypertension, and MetS was reduced (P<0.001 for all). There were no changes in the use of psychopharmaceutical drugs (20.6 vs. 18.8 %, P=0.549) or in the proportion of unemployed participants (37.7 vs. 33.3 %, P=0.189) from pre- to post-surgery. Eighty-three percent achieved EWL ≥50 %. These subjects had a lower presurgery BMI. We found no differences in the prevalence of hypertension, T2DM, and MetS pre-surgery, but the prevalence was lower after surgery compared with subjects with EWL <50 %. Conclusion RYGB induced remission of T2DM, hypertension, and MetS 2 years after surgery. The benefit was greatest in the group with EWL ≥50 %. Despite excellent weight loss, there was no change in the use of psychopharmaceutical drugs or proportion of unemployed participants.

• Aas, Anne-Marie; Johansson, Lars; Bjerkan, Kirsti; Lorentsen, Nina & Mostad, Ingrid Løvold (2013). Do Norwegians with diabetes have a healthier diet than the general population? Norsk Epidemiologi. ISSN 0803-2491. 23(1), p. 61–74. doi: 10.5324/nje.v23i1.1604. Full text in Research Archive
• Aas, Anne-Marie; Hanssen, Kristian Folkvord; Berg, Jens Petter; Thorsby, Per Medbøe & Birkeland, Kåre I. (2009). Insulin-Stimulated Increase in Serum Leptin Levels Precedes and Correlates with Weight Gain during Insulin Therapy in Type 2 Diabetes. Journal of Clinical Endocrinology and Metabolism (JCEM). ISSN 0021-972X. 94(8), p. 2900–2906. doi: 10.1210/jc.2008-1005.
• Aas, Anne Marie; Bergstad, I.; Thorsby, Per M; Johannesen, O.; Solberg, Martin & Birkeland, Kåre I (2005). An intensified lifestyle intervention programme may be superior to insulin treatment in poorly controlled Type 2 diabetic patients on oral hypoglycaemic agents : results of a feasibility study. Diabetic Medicine. ISSN 0742-3071. 22(3), p. 316–322. Show summary

  Conclusions Lifestyle intervention was as effective as insulin treatment in improving glycaemic control in poorly controlled subjects with Type 2 diabetes, and resulted in weight loss during the intervention year. However, glycaemic control deteriorated and body weight increased in the lifestyle intervention group 1 year after the intervention stopped.

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• Rishaug, Tina; Aas, Anne-Marie; Henriksen, André; Hartvigsen, Gunnar; Birkeland, Kåre Inge & Årsand, Eirik (2024). What are end-users' needs and preferences for a comprehensive e-health program for type 2 diabetes? - A qualitative user preference study.
• Rishaug, Tina; Henriksen, André; Aas, Anne-Marie; Hartvigsen, Gunnar; Birkeland, Kåre Inge & Årsand, Eirik (2024). DiAchieve: Preliminary Results from a Study on End-Users' Preferences for a Novel E-Health Program for Type 2 Diabetes.
• Rishaug, Tina; Henriksen, André; Aas, Anne-Marie; Hartvigsen, Gunnar; Birkeland, Kåre Inge & Årsand, Eirik (2024). DiAchieve: Preliminary Results from a Study on End-Users' Preferences for a Novel E-Health Program for Type 2 Diabetes. Diabetes Technology & Therapeutics. ISSN 1520-9156. 26(S2).
• Reynolds, Andrew N.; Kahleova, Hana; Uusitupa, Matti; Hermansen, Kjeld; Aas, Anne-Marie & Schwab, Ursula [Show all 10 contributors for this article] (2023). Not all very-low-carbohydrate diets are created equal. Reply to Conte C, Camajani E, Lai A, Caprio M [letter]. Diabetologia. ISSN 0012-186X. 66(9), p. 1754–1755. doi: 10.1007/s00125-023-05963-y.
• Rishaug, Tina; Henriksen, André; Aas, Anne-Marie; Hartvigsen, Gunnar; Birkeland, Kåre Inge & Årsand, Eirik (2023). DiAchieve - A Qualitative Pre-Study.
• Rishaug, Tina; Henriksen, André; Aas, Anne-Marie; Hartvigsen, Gunnar; Birkeland, Kåre Inge & Årsand, Eirik (2023). DiAchieve - A New e-Health Lifestyle Program for Improved Self-Management and Remission of Type 2 Diabetes.
• Rishaug, Tina; Henriksen, André; Aas, Anne-Marie; Hartvigsen, Gunnar; Birkeland, Kåre Inge & Årsand, Eirik (2023). Involving end users in the design and development of an e-health program for lifestyle changes in type 2 diabetes.
• Rishaug, Tina; Henriksen, André; Aas, Anne-Marie; Hartvigsen, Gunnar; Birkeland, Kåre Inge & Årsand, Eirik (2023). Involving end users in the design and development of an e-health program for lifestyle changes in type 2 diabetes. Diabetes Technology & Therapeutics. ISSN 1520-9156. doi: 10.1089/dia.2023.2525.abstracts.
• Zerouga, Insaf; Sommer, Christine; Carlsen, Monica Hauger; Valeur, Jørgen; Kristensen, Vendel Ailin & Høivik, Marte Lie [Show all 8 contributors for this article] (2023). Kosthold og ernæringsstatus ved nydiagostisert IBD: resultater fra IBSEN III.
• Rishaug, Tina; Henriksen, André; Aas, Anne-Marie; Hartvigsen, Gunnar; Birkeland, Kåre Inge & Årsand, Eirik (2022). Designing an e-Health Program for Lifestyle Changes in Diabetes Care: A Qualitative Pre-Study in Norway.
• Olsen, Sissel Urke; Hesseberg, Karin; Aas, Anne-Marie; Pripp, Are Hugo; Ranhoff, Anette Hylen & Bye, Asta (2022). Correction to: A comparison of two different refeeding protocols and its effect on hand grip strength and refeeding syndrome: a randomized controlled clinical trial (European Geriatric Medicine, (2021), 12, 6, (1201-1212), 10.1007/s41999-021-00520-5). European Geriatric Medicine. ISSN 1878-7649. 13, p. 1231–1232. doi: 10.1007/s41999-022-00653-1.
• Birkeland, Eline; Gharagozlian, Sedegheh; Birkeland, Kåre I.; Valeur, Jørgen; Måge, Ingrid & Rud, Ida [Show all 7 contributors for this article] (2020). Correction to: Prebiotic effect of inulin‑type fructans on faecal microbiota and short‑chain fatty acids in type 2 diabetes: a randomised controlled trial. European Journal of Nutrition. ISSN 1436-6207. doi: 10.1007/s00394-020-02314-0.
• Bernhoft, Aksel; Midtvedt, Tore; Eggesbø, Merete Åse; Aas, Anne-Marie; Berstad, Arnold & Harstad, Odd Magne [Show all 15 contributors for this article] (2017). Tarmens viktige mikrober - hvordan mater vi dem, og hva gjør de med oss? Årbok 2016 Det Norske Videnskaps-Akademi. Novus Forlag. ISSN 978-82-7099-888-3. p. 438–453.
• Bernhoft, Aksel; Berstad, Arnold; Eggesbø, Merete Åse; Garborg, Kjetil Kjeldstad; Harstad, Odd Magne & Holst-Jensen, Arne [Show all 15 contributors for this article] (2017). Tarmens viktige mikrober. Del III: Kan avføring brukes som behandling mot sykdommer? Forskning.no. ISSN 1891-635X.
• Bernhoft, Aksel; Berstad, Arnold; Eggesbø, Merete Åse; Garborg, Kjetil Kjeldstad; Harstad, Odd Magne & Holst-Jensen, Arne [Show all 15 contributors for this article] (2017). Tarmens viktige mikrober. Del II: Disse sykdommene kan kobles til det som bor i tarmen. Forskning.no. ISSN 1891-635X.
• Bernhoft, Aksel; Berstad, Arnold; Eggesbø, Merete Åse; Garborg, Kjetil Kjeldstad; Harstad, Odd Magne & Holst-Jensen, Arne [Show all 15 contributors for this article] (2017). Tarmens viktige mikrober. Del I: Tarmens viktige mikrober har stor betydning for helsen. Forskning.no. ISSN 1891-635X.
• Thorsby, Per M; Gjerlaugsen, Nina; Fosnes, Kjetil; Aas, Anne Marie; Midthjell, Kristian & Krüger, Øystein [Show all 9 contributors for this article] (2003). Undersøkelse av innflytelsen av en variasjon PPAR-g genet på vektutvikling og diabetes.
• Birkeland, Kåre I.; Aas, Anne-Marie; Johannesen, Øyvind; Thorsby, Per & Berg, Jens Petter (2002). The Leptin-stimulating effect of insulin relates to weight gain during long term insulin treatment in type 2 diabetes.
• Aas, Anne-Marie; Bergstad, I.; Johannesen, Øyvind; Thorsby, Per & Birkeland, Kåre I. (2002). Long term insulin treatment stimulates leptin production and precedes weight gain in type 2 diabetic patients.

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