Maria Vistnes

• Andrup, Simon Johan Mattias; Andersen, Geir Øystein; Hoffmann, Pavel; Eritsland, Jan; Seljeflot, Ingebjørg & Halvorsen, Sigrun [Show all 7 contributors for this article] (2024). Novel cardiac extracellular matrix biomarkers in STEMI: Associations with ischemic injury and long-term mortality. PLOS ONE. ISSN 1932-6203. 19(5). doi: 10.1371/journal.pone.0302732.
• Thorlacius, Elin M.; Keski-Nisula, Juho; Vistnes, Maria; Ojala, Tiina; Molin, Mattias & Synnergren, Mats [Show all 10 contributors for this article] (2024). High-sensitive troponinT, interleukin-8, and interleukin-6 link with post-surgery risk in infant heart surgery. Acta Anaesthesiologica Scandinavica. ISSN 0001-5172. doi: 10.1111/aas.14405.
• Vistnes, Maria (2024). Hitting the Target! Challenges and Opportunities for TGF-β Inhibition for the Treatment of Cardiac fibrosis. Pharmaceuticals. ISSN 1424-8247. 17(3). doi: 10.3390/ph17030267.
• Sasi, Athiramol; Romaine, Andreas; Murugan Erusappan, Pugazendhi; Melleby, Arne Olav; Hasic, Almira & Dahl, Christen Peder [Show all 14 contributors for this article] (2023). Temporal expression and spatial distribution of the proteoglycan versican during cardiac fibrosis development. Matrix Biology Plus. 19-20. doi: 10.1016/j.mbplus.2023.100135. Full text in Research Archive
• Vistnes, Maria; Murugan Erusappan, Pugazendhi; Sasi, Athiramol; Nordén, Einar Sjaastad; Bergo, Kaja Knudsen & Romaine, Andreas [Show all 22 contributors for this article] (2023). Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction. Cardiovascular Research (CVR). ISSN 0008-6363. 119(10), p. 1915–1927. doi: 10.1093/cvr/cvad078. Full text in Research Archive
• Gløersen, Marthe; Pettersen, Pernille Steen; Neogi, Tuhina; Jafarzadeh, S. Reza; Vistnes, Maria & Thudium, Christian S. [Show all 11 contributors for this article] (2022). Associations of Body Mass Index With Pain and the Mediating Role of Inflammatory Biomarkers in People With Hand Osteoarthritis. Arthritis & Rheumatology. ISSN 2326-5191. 74(5), p. 810–817. doi: 10.1002/art.42056. Full text in Research Archive
• Thorlacius, Elin M; Vistnes, Maria; Ojala, Tiina; Keski-Nisula, Juho; Molin, Mattias & Romlin, Birgitta S [Show all 10 contributors for this article] (2021). Levosimendan Versus Milrinone and Release of Myocardial Biomarkers After Pediatric Cardiac Surgery: Post Hoc Analysis of Clinical Trial Data. Pediatric Critical Care Medicine. ISSN 1529-7535. 22(7), p. 402–409. doi: 10.1097/PCC.0000000000002712. Show summary

  Objectives: We compared the effect of two inodilators, levosimendan and milrinone, on the plasma levels of myocardial injury biomarkers, that is, high-sensitivity troponin T and heart-type fatty acid binding protein, and on N-terminal prohormone of brain natriuretic peptide as a biomarker of ventricular function. We hypothesized that levosimendan could attenuate the degree of myocardial injury when compared with milrinone. Design: A post hoc, nonprespecified exploratory secondary analysis of the Milrinone versus Levosimendan-1 trial (ClinicalTrials.gov Identifier: NCT02232399). Setting: Two pediatric tertiary university hospitals. Patients: Infants 1-12 months old, diagnosed with ventricular septal defect, complete atrioventricular septal defect, or Tetralogy of Fallot undergoing corrective surgery with cardiopulmonary bypass. Interventions: Seventy patients received a loading dose of either levosimendan or milrinone at the start of cardiopulmonary bypass followed by an infusion of the respective drug, which continued for 26 hours. Measurements and main results: Plasma levels of the three cardiac biomarkers were measured prior to the initiation of cardiopulmonary bypass and 2, 6, and 24 hours after weaning from cardiopulmonary bypass. In both groups, the levels of high-sensitivity troponin T and heart-type fatty acid binding protein were highest at 2 hours post cardiopulmonary bypass, whereas the highest level of N-terminal prohormone of brain natriuretic peptide occurred at 24 hours post cardiopulmonary bypass. There was no significant difference in the biomarkers' plasma levels between the study groups over time. Neither was there a significant difference in the postoperative peak plasma levels of the cardiac biomarkers. Conclusions: In this post hoc analysis of the MiLe-1 trial, there was no demonstrable difference in the postoperative cardiac biomarker profile of myocardial injury and ventricular function when comparing infants managed in the perioperative period with levosimendan versus milrinone.

• Hetland, Sveinung Arild; Vistnes, Maria; Haugaa, Kristina; Liland, Kristian Hovde; Olseng, Margareth & Edvardsen, Thor (2020). Obstructive sleep apnea versus central sleep apnea: prognosis in systolic heart failure. Cardiovascular Diagnosis and Therapy (CDT). ISSN 2223-3652. 10(3), p. 396–404. doi: 10.21037/cdt.2020.03.02. Full text in Research Archive
• Krogstad, Veronica; Peric, Alexandra; Robertsen, Ida; Kringen, Marianne K.; Vistnes, Maria & Hjelmesæth, Jøran [Show all 15 contributors for this article] (2020). Correlation of body weight and composition with hepatic activities of cytochrome P450 enzymes . Journal of Pharmaceutical Sciences. ISSN 0022-3549. 110(1), p. 432–437. doi: 10.1016/j.xphs.2020.10.027. Full text in Research Archive
• Thorlacius, Elin M; Suominen, Pertti K; Wahlander, Hakan; Keski-Nisula, Juho; Vistnes, Maria & Ricksten, Sven-Erik [Show all 9 contributors for this article] (2019). The Effect of Levosimendan Versus Milrinone on the Occurrence Rate of Acute Kidney Injury Following Congenital Heart Surgery in Infants: A Randomized Clinical Trial. Pediatric Critical Care Medicine. ISSN 1529-7535. 20(10), p. 947–956. doi: 10.1097/PCC.0000000000002017.
• Hazen, Josje; Vistnes, Maria; Barca, Maria Lage; Eldholm, Rannveig Sakshaug; Persson, Karin Ester Torun & Brækhus, Anne [Show all 10 contributors for this article] (2019). The Association Between Circulating Inflammatory Markers and the Progression of Alzheimer Disease in Norwegian Memory Clinic Patients With Mild Cognitive Impairment or Dementia. Alzheimer Disease and Associated Disorders. ISSN 0893-0341. doi: 10.1097/WAD.0000000000000342. Show summary

  OBJECTIVE: Neuroinflammation may play an important role in the pathogenesis and progression of Alzheimer disease (AD). The aim of the present study was to detect whether increased inflammatory activity at baseline could predict cognitive and functional decline in patients with amnestic mild cognitive impairment (aMCI) or AD dementia after 2 years. METHODS: Serum samples from 242 memory clinic patients with an aMCI (n=88) or AD dementia (n=154) were analyzed for C-reactive protein and for 14 other inflammatory markers [interleukin (IL)-1β, interleukin-1 receptor antagonist, IL-6, IL-10, IL-12p40, IL-17a, IL-18, IL-22, IL-33, tumor necrosis factor, cluster of differentiation 40 ligand, interferon-γ, chemokine ligand (CCL) 2, and CCL4] by bead-based multiplex immunoassay. Disease progression was measured by the annual increase in the Clinical Dementia Rating Scale Sum of Boxes (CDR-SB) and annual decrease in the score on the Mini-Mental State Examination (MMSE). RESULTS: No association between increased levels of the inflammatory markers and change on the CDR-SB or MMSE score was found, but there was a significant difference in baseline IL-6 and interleukin-1 receptor antagonist levels between aMCI and AD dementia groups. CONCLUSION: Increased levels of inflammatory markers were not associated with faster progression as measured by the annual change on the CDR-SB or MMSE score.

• Kononova, Natalia; Sikkeland, Liv Ingunn Bjoner; Mahmood, Faiza; Vistnes, Maria; Kongerud, Johny & Einvik, Gunnar [Show all 7 contributors for this article] (2019). Annual decline in forced expiratory volume and airway inflammatory cells and mediators in a general population-based sample. BMC Pulmonary Medicine. ISSN 1471-2466. 19. doi: 10.1186/s12890-018-0765-7. Full text in Research Archive
• Wollmann, Birgit Malene Tovik; Syversen, Silje Watterdal; Vistnes, Maria; Lie, Elisabeth; Mehus, Lise Larsen & Molden, Espen (2018). Associations between cytokine levels and CYP3A4 phenotype in patients with rheumatoid arthritis. Drug Metabolism And Disposition. ISSN 0090-9556. 46(10), p. 1384–1389. doi: 10.1124/dmd.118.082065.
• Vistnes, Maria; Tapia, German; Mårild, Karl Staffan; Midttun, Øivind; Ueland, Per Magne & Viken, Marte K [Show all 14 contributors for this article] (2017). Plasma immunological markers in pregnancy and cord blood: A possible link between macrophage chemo-attractants and risk of childhood type 1 diabetes. American journal of reproductive immunology. ISSN 1046-7408. 79(3). doi: 10.1111/aji.12802.
• Hetland, Sveinung Arild; Haugaa, Kristina; Vistnes, Maria; Liland, Kristian Hovde; Olseng, Margareth & Jacobsen, Morten [Show all 7 contributors for this article] (2017). A retrospective analysis of cardiovascular outcomes in patients treated with ASV. Scandinavian Cardiovascular Journal. ISSN 1401-7431. 51(2), p. 106–113. doi: 10.1080/14017431.2016.1262546.
• Schwartz, Thomas; Sjaastad, Ivar; Flatø, Berit; Vistnes, Maria; Christensen, Geir Arve & Sanner, Helga (2014). In active juvenile dermatomyositis, elevated eotaxin and MCP-1 and cholesterol levels in the upper normal range are associated with Cardiac dysfunction. Rheumatology (Sveits). ISSN 0080-2727. 53, p. 2214–2222. doi: 10.1093/rheumatology/keu256.
• Sanner, Helga; Schwartz, Thomas; Flatø, Berit; Vistnes, Maria; Christensen, Geir Arve & Sjaastad, Ivar (2014). Increased levels of eotaxin and MCP-1 in juvenile dermatomyositis median 16.8 years after disease onset; associations with disease activity, duration and organ damage. PLOS ONE. ISSN 1932-6203. 9(3). doi: 10.1371/journal.pone.0092171.
• Vistnes, Maria; Aronsen, Jan Magnus; Lunde, Ida Gjervold; Sjaastad, Ivar; Carlson, Cathrine Rein & Christensen, Geir Arve (2014). Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding. PLOS ONE. ISSN 1932-6203. 9(3). doi: 10.1371/journal.pone.0089621.
• Strand, Mari Elen; Herum, Kate Louise Møller; Rana, Zaheer Ahmad; Skrbic, Biljana; Askevold, Erik Tandberg & Dahl, Christen Peder [Show all 15 contributors for this article] (2013). Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart. The FEBS Journal. ISSN 1742-464X. 280(10), p. 2228–2247. doi: 10.1111/febs.12161.
• Vistnes, Maria; Høiseth, Arne Didrik; Røsjø, Helge; Nygård, Ståle; Pettersen, Eirik & Søyseth, Vidar [Show all 9 contributors for this article] (2013). Lack of pro-inflammatory cytokine mobilization predicts poor prognosis in patients with acute heart failure. Cytokine. ISSN 1043-4666. 61(3), p. 962–969. doi: 10.1016/j.cyto.2013.01.006.
• Einvik, Gunnar; Vistnes, Maria; Hrubos-Strøm, Harald; Randby, Anna; Namtvedt, Silje Kjeka & Nordhus, Inger Hilde [Show all 9 contributors for this article] (2012). Circulating cytokine concentrations are not associated with major depressive disorder in a community-based cohort. General Hospital Psychiatry. ISSN 0163-8343. 34(3), p. 262–267. doi: 10.1016/j.genhosppsych.2012.01.017.
• Wæhre, Anne; Vistnes, Maria; Sjaastad, Ivar; Nygård, Ståle; Husberg, Cathrine & Lunde, Ida Gjervold [Show all 14 contributors for this article] (2012). Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle. Journal of applied physiology. ISSN 8750-7587. 112(8), p. 1372–1382. doi: 10.1152/japplphysiol.01350.2011.
• Vistnes, Maria; Christensen, Geir Arve & Omland, Torbjørn (2010). Multiple cytokine biomarkers in heart failure. Expert Review of Molecular Diagnostics. ISSN 1473-7159. 10(2), p. 147–157. doi: 10.1586/ERM.10.3.
• Vistnes, Maria; Wæhre, Anne; Nygård, Ståle; Sjaastad, Ivar; Andersson, Kristin Brevik & Husberg, Cathrine [Show all 7 contributors for this article] (2010). Circulating cytokine levels in mice with heart failure are etiology dependent. Journal of applied physiology. ISSN 8750-7587. 108(5), p. 1357–1364. doi: 10.1152/japplphysiol.01084.2009.

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• Vistnes, Maria (2024). Survival of the strongest: Can muscular strength measurements be used in prevention of heart failure in patients with acute coronary syndromes? European Journal of Preventive Cardiology (EJPC). ISSN 2047-4873. 31(7), p. 832–833. doi: 10.1093/eurjpc/zwae047.
• Vistnes, Maria (2023). Hvordan kan oppfølgingen av pasienter med hjertesvikt bli bedre? Tidsskrift for Den norske legeforening. ISSN 0029-2001. 143(17). doi: 10.4045/tidsskr.23.0735.
• Persson, Karin Ester Torun; Barca, Maria Lage; Eldholm, Rannveig Sakshaug; Knapskog, Anne Brita; Vistnes, Maria & Cavallin, Lena [Show all 12 contributors for this article] (2018). MRI assessed atrophy subtypes in Alzheimer’s disease with mild degree of dementia.
• Mårild, Karl; Vistnes, Maria; Tapia, German; Midttun, Øivind; Ueland, Per Magne & Viken, Marte K [Show all 10 contributors for this article] (2017). Midpregnancy and cord blood immunologic biomarkers, HLA genotype, and pediatric celiac disease. Journal of Allergy and Clinical Immunology. ISSN 0091-6749. 139(5), p. 1696–1698. doi: 10.1016/j.jaci.2016.10.016.
• Strand, Mari Elen; Herum, Kate Louise Møller; Rana, Z.A.; Skrbic, Biljana; Askevold, Erik Tandberg & Dahl, Christen Peder [Show all 10 contributors for this article] (2014). Cardiac Expression and shedding of the transmembrane heparan sulphate proteoglycan syndecan-4 is induced by innate immune signalling, affecting inflammation and heart failure progression. European Journal of Heart Failure. Supplements. ISSN 1567-4215. 16, p. S41–S41.
• Hetland, Arild; Haugaa, Kristina H.; Vistnes, Maria; Liland, Kristian Hovde; Olseng, Margareth & Jacobsen, Morten B. [Show all 7 contributors for this article] (2014). Adaptive Servo-Ventilation Decreased Mortality and Admission Rates in Heart Failure Patients With Cheyne-Stokes Respiration in a 18 Months Prospective Study.
• Strand, Mari Elen; Herum, Kate Louise Møller; Rana, Zaheer Ahmad; Skrbic, Biljana; Askevold, Erik Tandberg & Dahl, C.P. [Show all 10 contributors for this article] (2013). Cardiac expression and shedding of the transmembrane heparan sulphate proteoglycan syndecan-4 is induced by innate immunity signalling, affecting inflammation and heart failure progression. European Journal of Heart Failure. Supplements. ISSN 1567-4215. 12(1), p. S41–S41.
• Schwartz, Thomas; Sjaastad, Ivar; Flatø, Berit; Vistnes, Maria; Christensen, Geir Arve & Sanner, Helga (2012). Monocyte Chemoattractant Protein-1 and Eotaxin Are Associated with Parameters of Cardiac Dysfunction in Juvenile Dermatomyositis. Arthritis and Rheumatism. ISSN 0004-3591. 64(10), p. S381–S381.
• Strand, Mari Elen; Herum, Kate Louise Møller; Rana, Zaheer Ahmad; Skrbic, Biljana; Vistnes, Maria & Sjaastad, Ivar [Show all 10 contributors for this article] (2012). The adhesion site transmembrane proteoglycan syndecan-4; an integrator of pro-hypertrophic and pro-inflammatory signaling in the heart? Circulation. ISSN 0009-7322. 126.
• Strand, Mari Elen; Herum, Kate Louise Møller; Rana, Zaheer Ahmad; Skrbic, Biljana; Vistnes, Maria & Hasic, Almira [Show all 12 contributors for this article] (2012). The adhesion site transmembrane proteoglycan syndecan-4; an integrator of pro-hypertrophic and pro-inflammatory signaling in the heart?
• Vistnes, Maria; Lunde, Ida Gjervold; Aronsen, Jan Magnus; Sjaastad, Ivar & Christensen, Geir Arve (2011). Cardiac expression of ADAMTS1 is increased during transition to failure.
• Schwartz, Thomas; Sanner, Helga; Vistnes, Maria; Christensen, Geir Arve; Flatø, Berit & Sjaastad, Ivar (2011). Increased levels of MCP-1 and eotaxin are associated with cardiac dysfunction in juvenile dermatomyositis.
• Wæhre, Anne; Vistnes, Maria; Sjaastad, Ivar; Nygård, Ståle; Husberg, Cathrine & Lunde, Ida Gjervold [Show all 11 contributors for this article] (2011). Chemokines regulate small leucine-rich proteins in the extracellular matrix of the pressure overload right ventricle.
• Vistnes, Maria; Lunde, Ida Gjervold; Aronsen, Jan Magnus; Sjaastad, Ivar; Carlson, Cathrine Rein & Tønnessen, Theis [Show all 7 contributors for this article] (2011). Enhanced expression of versican, aggrecan and ADAMTS versicanases and aggrecanases during development of myocardial hypertrophy and heart failure.
• Vistnes, Maria; Wæhre, Anne; Sjaastad, Ivar; Nygård, Ståle; Husberg, Cathrine & Christensen, Geir Arve (2010). Circulating cytokines in heart failure.
• Vistnes, Maria (2012). Cytokines and extracellular matrix in heart failure. Unipub forlag. ISSN 978-82-8264-493-8.

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