Stig Müller

• Albertsen, Peter C.; Bjerner, Lars Johan; Pasovic, Lara; Müller, Stig; Fosså, Sophie Dorothea & Carlsson, Sigrid V. (2023). Opportunistic prostate-specific antigen testing in Norwegian men: a public health challenge. BJU International. ISSN 1464-4096. 133(1), p. 104–111. doi: 10.1111/bju.16211.
• Bjerner, Lars; Bratt, Ola; Aas, Kirsti; Albertsen, Peter C.; Fosså, Sophie D. & Kvåle, Rune [Show all 16 contributors for this article] (2023). Baseline Serum Prostate-specific Antigen Value Predicts the Risk of Subsequent Prostate Cancer Death—Results from the Norwegian Prostate Cancer Consortium. European Urology. ISSN 0302-2838. p. 1–7. doi: 10.1016/j.eururo.2023.04.028.
• Tahiri, Andliena; Puco, Katarina; Naji, Faris; Kristensen, Vessela N.; Alfsen, G. Cecilie & Farkas, Lorant [Show all 10 contributors for this article] (2022). Kinase activity profiling in renal cell carcinoma, benign renal tissue and in response to four different tyrosine kinase inhibitors. OncoTarget. ISSN 1949-2553. 13(1), p. 970–981. doi: 10.18632/oncotarget.28257. Full text in Research Archive Show summary

  Kinase activity is frequently altered in renal cell carcinoma (RCC), and tyrosine kinase inhibitors (TKIs) are part of the standard treatment strategy in patients with metastatic disease. However, there are still no established biomarkers to predict clinical benefits of a specific TKI. Here, we performed protein tyrosine kinase (PTK) profiling using PamChip® technology. The aim of this study was to identify differences in PTK activity between normal and malignant kidney tissue obtained from the same patient, and to investigate the inhibitory effects of TKIs frequently used in the clinics: sunitinib, pazopanib, cabozantinib and tivozanib. Briefly, our results showed that 36 kinase substrates differs (FDR < 0.05) between normal and cancer kidney tissue, where members of the Src family kinases and the phosphoinositide-3-kinase (PI3K) pathway exhibit high activity in renal cancer. Furthermore, ex vivo treatment of clear cell RCC with TKIs revealed that pathways such as Rap1, Ras and PI3K pathways were strongly inhibited, whereas the neurotrophin pathway had increased activity upon TKI addition. In our assay, tivozanib and cabozantinib exhibited greater inhibitory effects on PTK activity compared to sunitinib and pazopanib, implying they might be better suitable as TKIs for selected RCC patients.

• Aas, Kirsti; Fosså, Sophie Dorothea; Kvåle, Rune; Møller, Bjørn; Myklebust, Tor Åge & Vlatkovic, Ljiljana [Show all 8 contributors for this article] (2018). Is time from diagnosis to radical prostatectomy associated with oncological outcomes? . World Journal of Urology. ISSN 0724-4983. 37(8), p. 1571–1580. doi: 10.1007/s00345-018-2570-6.
• Müller, Stig; Lilleaasen, Gunder; Sand, Tor-Erik; Løfsgaard, Lars; Estop-Garanto, Manuela & Helgø, Dan [Show all 8 contributors for this article] (2018). Poor reproducibility of PIRADS score in two multiparametric MRIs before biopsy in men with elevated PSA. World Journal of Urology. ISSN 0724-4983. 36(5), p. 687–691. doi: 10.1007/s00345-018-2252-4.
• Jacobsen Løvvik, Anja; Müller, Stig & Patel, Hitendra R.H. (2016). Pharmacological Treatment of Post-Prostatectomy Incontinence: What is the Evidence? Drugs & Aging. ISSN 1170-229X. 33(8), p. 535–544. doi: 10.1007/s40266-016-0388-8.
• Patel, Hitendra R.H.; Santos, Pedro; de Oliveira, Manuel Castanheira & Müller, Stig (2016). Is robotic-assisted radical cystectomy (RARC) with intracorporeal diversion becoming the new gold standard of care? World Journal of Urology. ISSN 0724-4983. 34(1), p. 25–32. doi: 10.1007/s00345-015-1730-1.
• Müller, Stig; Grønning, Leif Erik; Nilsen, Frode S; Mygland, Vegard & Patel, Hitendra R.H. (2014). Robotic and minimal access surgery: Technology and surgical outcomes of radical prostatectomy for prostate cancer. Expert Review of Anticancer Therapy. ISSN 1473-7140. 14(11), p. 1317–1321. doi: 10.1586/14737140.2014.965689.
• Nicolaisen, Marianne; Müller, Stig; Patel, Hitendra R.H. & Hanssen, Tove Aminda (2014). Quality of life and satisfaction with information after radical prostatectomy, radical external beam radiotherapy and postoperative radiotherapy: a long-term follow-up study. Journal of Clinical Nursing (JCN). ISSN 0962-1067. 23(23-24), p. 3403–3414. doi: 10.1111/jocn.12586.
• Cerantola, Yannick; Valerio, Massimo; Persson, Beata; Jichlinski, Patrice; Ljungqvist, Olle & Hubner, Martin [Show all 18 contributors for this article] (2013). Guidelines for perioperative care after radical cystectomy for bladder cancer: Enhanced Recovery After Surgery (ERAS®) society recommendations. Clinical Nutrition. ISSN 0261-5614. 32(6), p. 879–887. doi: 10.1016/j.clnu.2013.09.014.
• Kilminster, Shaun; Müller, Stig; Menon, Mani; Joseph, Jean V.; Ralph, David J. & Patel, Hitendra R.H. (2012). Predicting erectile function outcome in men after radical prostatectomy for prostate cancer. BJU International. ISSN 1464-4096. 110(3), p. 422–426. doi: 10.1111/j.1464-410X.2011.10757.x.
• Müller, Stig; How, Ole-Jakob; Jakobsen, Øyvind; Hermansen, Stig Eggen; Røsner, Assami & Stenberg, Thor Allan [Show all 7 contributors for this article] (2010). Oxygen-Wasting Effect of Inotropy Is There a Need for a New Evaluation? An Experimental Large-Animal Study Using Dobutamine and Levosimendan. Circulation: Heart Failure. ISSN 1941-3289. 3(2), p. 277–285. doi: 10.1161/CIRCHEARTFAILURE.109.865519.
• Rösner, A; Bijnens, B; Hansen, Magna; How, Ole-Jakob; Aarsæther, Erling Johan & Müller, Stig [Show all 8 contributors for this article] (2009). Left ventricular size determines tissue Doppler-derived longitudinal strain and strain rate. European Heart Journal-Cardiovascular Imaging. ISSN 2047-2404. 10(2), p. 271–277. doi: 10.1093/ejechocard/jen230.
• Müller, Stig; How, Ole-Jakob; Hermansen, Stig eggen; Stenberg, Thor Allan; Sager, Georg & Myrmel, truls (2008). Vasopressin impairs brain, heart and kidney perfusion: an experimental study in pigs after transient myocardial ischemia. Critical Care. ISSN 1364-8535. 12. doi: 10.1186/cc6794.
• Hermansen, Stig eggen; Myrmel, truls; Hansen, Magna; How, Ole-Jakob; Müller, Stig & Roaldsen, Marius Håke (2008). How many acute heart failure patients need a ventricular assist device? Scandinavian Cardiovascular Journal. ISSN 1401-7431. 42, p. 118–124. doi: 10.1080/14017430701819113.
• Hermansen, Stig eggen; Hansen, Magna; Roaldsen, Marius Håke; Müller, Stig; How, Ole-Jakob & Myrmel, truls (2008). Utilization and outcome of coronary revascularization and valve procedures in acute heart failure – an evaluation based on the classification from the European Society of Cardiology. Interactive Cardiovascular and Thoracic Surgery. ISSN 1569-9293. 7, p. 833–838. doi: 10.1510/icvts.2008.175067.
• Røsner, Assami; Bijnens, B; Hansen, Magna; How, Ole-Jakob; Aarsæther, Erling Johan & Müller, Stig [Show all 8 contributors for this article] (2008). Left ventricular size determines tissue Doppler-derived longitudinal strain and strain rate. European Heart Journal-Cardiovascular Imaging. ISSN 2047-2404.
• Kjorstad, KE; Kjørstad, Knut Eivind; Nordhaug, dag ole; Korvald, Christian; Muller, S & Müller, Stig [Show all 8 contributors for this article] (2007). Mechanical restitution curves - a possible load independent assessment of contractile function. European Journal of Cardio-Thoracic Surgery. ISSN 1010-7940. 31( ), p. 677–684. doi: 10.1016/j.ejcts.2007.01.013.
• Jakobsen, Øyvind; Müller, Stig; Aarsæther, Erling Johan; Steensrud, Tor & Sørlie, Dag Glen (2007). Adenosine instead of supranormal potassium in cardioplegic solution improves cardioprotection. European Journal of Cardio-Thoracic Surgery. ISSN 1010-7940. 32(3), p. 493–500. doi: 10.1016/j.ejcts.2007.05.020.

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• Aas, Kirsti; Fosså, Sophie Dorothea; Kvåle, Rune; Møller, Bjørn; Myklebust, Tor Åge & Vlatkovic, Ljiljana [Show all 8 contributors for this article] (2018). Increasing Time from Diagnosis to Radical Prostatectomy (RP-interval) is Not Associated with Adverse Oncological Outcomes: Implications for cancer patient pathways (CPPs). European Urology. Supplement. ISSN 1569-9056. 17(14), p. e2825–e2827. doi: 10.1016/S1569-9056(18)33709-6.
• Patel, Hitendra R.H.; Cerantola, Yannick; Valerio, Massimo; Persson, Beata; Jichlinski, Patrice & Ljungqvist, Olle [Show all 19 contributors for this article] (2014). Enhanced recovery after surgery: are we ready, and can we afford not to implement these pathways for patients undergoing radical cystectomy? European Urology. ISSN 0302-2838. 65(2), p. 263–266. doi: 10.1016/j.eururo.2013.10.011.
• Müller, Stig; Jakobsen, O; How, Ole-Jakob & Myrmel, truls (2007). Levosimendan improves mechanical efficiency in stunned pig hearts. European Journal of Heart Failure. ISSN 1388-9842. 6.

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