Torstein Egeland

• Hajdarevic, Riad; Lande, Asgeir; Rekeland, Ingrid Gurvin; Rydland, Anne; Strand, Elin Bolle & Sosa , Daysi Duarte [Show all 13 contributors for this article] (2021). Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests involvement of both HLA class I and class II loci. Brain, Behavior, and Immunity. ISSN 0889-1591. 98, p. 101–109. doi: 10.1016/j.bbi.2021.08.219. Full text in Research Archive
• Lande, Asgeir; Fluge, Øystein; Strand, Elin Bolle; Flåm, Siri Tennebø; Daysi Duarte, Sosa & Mella, Olav [Show all 10 contributors for this article] (2020). Human Leukocyte Antigen Alleles Associated With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Scientific Reports. ISSN 2045-2322. 10:5267(1), p. 1–8. doi: 10.1038/s41598-020-62157-x. Full text in Research Archive
• Pahnke, Simon; Egeland, Torstein; Halter, Jörg; Hägglund, Hans; Shaw, Bronwen E. & Woolfrey, Ann E. [Show all 7 contributors for this article] (2018). Current use of biosimilar G-CSF for haematopoietic stem cell mobilisation. Bone Marrow Transplantation. ISSN 0268-3369. p. 1–9. doi: 10.1038/s41409-018-0350-y.
• van Walraven, Suzanna M.; Egeland, Torstein; Borrill, Veronica; Nicoloso-de Faveri, Grazia; Rall, Gabi & Szer, Jeff (2018). Addressing Ethical and Procedural Principles for Unrelated Allogeneic Hematopoietic Progenitor Cell Donation in a Changing Medical Environment. Biology of Blood and Marrow Transplantation. ISSN 1083-8791. 24(5), p. 887–894. doi: 10.1016/j.bbmt.2018.01.018.
• Lande, Asgeir; Andersen, Irene; Egeland, Torstein; Lie, Benedicte Alexandra & Viken, Marte K (2018). HLA -A, -C, -B, -DRB1, -DQB1 and -DPB1 allele and haplotype frequencies in 4514 healthy Norwegians. Human Immunology. ISSN 0198-8859. 79(7), p. 527–529. doi: 10.1016/j.humimm.2018.04.012.
• Dahl, Jesper; Refsum, Erle; Ahlen, Maria Therese; Egeland, Torstein; Jensen, Tore & Viken, Marte K [Show all 11 contributors for this article] (2017). Unraveling the role of maternal anti-HLA class I antibodies in fetal and neonatal thrombocytopenia?Antibody specificity analysis using epitope data. Journal of Reproductive Immunology. ISSN 0165-0378. 122, p. 1–9. doi: 10.1016/j.jri.2017.06.003.
• Stray-Pedersen, Asbjørg; Backe, Paul Hoff; Sorte, Hanne Sørmo; Mørkrid, Lars; Chokshi, N.Y. & Erichsen, Hans Christian [Show all 39 contributors for this article] (2014). PGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia. American Journal of Human Genetics. ISSN 0002-9297. 95(1), p. 96–107. doi: 10.1016/j.ajhg.2014.05.007.
• Petersdorf, Effie W.; Gooley, Theodore A.; Malkki, Mari; Bacigalupo, Andrea P.; Cesbron, Anne & Du Toit, Ernette [Show all 25 contributors for this article] (2014). HLA-C expression levels define permissible mismatches in hematopoietic cell transplantation. Blood. ISSN 0006-4971. 124(26), p. 3996–4003. doi: 10.1182/blood-2014-09-599969.
• Husøy, Magnus Andreas Rognlien; Brinch, Lorentz; Tjønnfjord, Geir Erland; Gedde-Dahl, Tobias Jr.; Heldal, Dag & Holme, Pål Andre [Show all 16 contributors for this article] (2014). Allogen stamcelletransplantasjon hos voksne 1985-2012. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 134(16), p. 1569–1575. doi: 10.4045/tidsskr.13.1415.
• Abrahamsen, Ingerid Weum; Kjellevoll, Synneva; Greve-Isdahl, Margrethe; Mensali, Nadia; Waelchli, Sebastien & Kumari, Shraddha [Show all 10 contributors for this article] (2012). T cells raised against allogeneic HLA-A2/CD20 kill primary follicular lymphoma and acute lymphoblastic leukemia cells. International Journal of Cancer. ISSN 0020-7136. 130(8), p. 1821–1832. doi: 10.1002/ijc.26209.
• Fløisand, Yngvar; Brinch, Lorentz; Gedde-Dahl, Thobias; Tjønnfjord, Geir Erland; Dybedal, Ingunn & Holte, Harald [Show all 18 contributors for this article] (2012). Ultra-short course sirolimus contributes to effective GVHD prophylaxis after reduced-intensity allogeneic hematopoietic cell transplantation. Bone Marrow Transplantation. ISSN 0268-3369. 47(12), p. 1552–1557. doi: 10.1038/bmt.2012.63.
• King, RJ; Confer, DL; Greinix, HT; Halter, J; Horowitz, M & Schmidt, AH [Show all 9 contributors for this article] (2011). Unrelated hematopoietic stem cell donors as research subjects. Bone Marrow Transplantation. ISSN 0268-3369. 46(1), p. 10–13. doi: 10.1038/bmt.2010.37.
• Boo, Michael; van Walraven, Suzanna M.; Chapman, Jeremy; Lindberg, Brian; Schmidt, Alexander H. & Shaw, Bronwen E. [Show all 9 contributors for this article] (2011). Remuneration of hematopoietic stem cell donors: principles and perspective of the World Marrow Donor Association. Blood. ISSN 0006-4971. 117(1), p. 21–25. doi: 10.1182/blood-2010-07-298430.
• Haned, H.; Egeland, Thore; Pontier, D.; Pène, L. & Gill, Peter (2011). Estimating drop-out probabilities in forensic DNA samples: A simulation approach to evaluate different models. Forensic Science International. ISSN 0379-0738. 5(5), p. 525–531. doi: 10.1016/j.fsigen.2010.12.002.
• Rofstad, Einar K; Gaustad, Jon-Vidar; Egeland, Torstein; Mathiesen, Berit & Galappathi, Kanthi (2010). Tumors exposed to acute cyclic hypoxic stress show enhanced angiogenesis, perfusion and metastatic dissemination. International Journal of Cancer. ISSN 0020-7136. 127(7), p. 1535–1546. doi: 10.1002/ijc.25176.
• Taraldsrud, Eli; Grøgaard, Haakon Kiil; Solheim, Svein; Lunde, Kjetil; Føisand, Y & Arnesen, Harald [Show all 8 contributors for this article] (2009). Age and stress related phenotypical changes in bone marrow CD34+cells. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 69(1), p. 79–84. doi: 10.1080/00365510802419447.
• Skinningsrud, Beate; Husebye, Eystein Sverre; Pearce, Simon H.; McDonald, David O.; Brandal, Kristin & Wolff, Anette Susanne Bøe [Show all 11 contributors for this article] (2008). Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency. Journal of Clinical Endocrinology and Metabolism (JCEM). ISSN 0021-972X. 93(9), p. 3310–3317. doi: 10.1210/jc.2008-0821.
• Grøgaard, Haakon Kiil; Sigurjonsson, Olafur; Brekke, Magne; Kløw, Nils; Landsverk, Kirsti & Lyberg, Torstein [Show all 9 contributors for this article] (2007). Cardiac accumulation of bone marrow mononuclear progenitor cells after intracoronary or intravenous injection in pigs subjected to acute myocardial infarction with subsequent reperfusion. Cardiovascular Revascularization Medicine. ISSN 1553-8389. 8, p. 21–27.
• Dalgaard, Jakob; Stenersen, Margurethe; Egeland, Torstein & Brinch, Lorentz (2007). Allogen stamcelletransplantasjon med redusert forbehandling. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 127, p. 721–724.
• Lunde, Ketil; Solheim, Svein; Aakhus, Svend; Arnesen, Harald; Moum, Torbjørn & Abdelnoor, Michael [Show all 11 contributors for this article] (2007). Exercise capacity and quality of life after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: Results from the Autologous Stem cell Transplantation in Acute Myocardial Infarction (ASTAMI) randomized controlled trial. American Heart Journal. ISSN 0002-8703. 154, p. 710.e1–710.e8. doi: 10.1016/j.ahj.2007.07.003.
• Sigurjonsson, Olaur E.; Perreault, Marie-Claude; Egeland, Torstein & Glover, Joel (2005). Adult human hematopoietic stem cells produce neurons efficiently in the regenerating chicken embryo spinal cord. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 102.
• Abrahamsen, IW; Somme, Stig; Heldal, Dag; Egeland, Torstein; Kvale, Dag & Tjønnfjord, Geir E (2005). Immune reconstitution after allogeneic stem cell transplantation: the impact of stem cell source and graft-versus-host disease. Haematologica. ISSN 0390-6078. 90.
• Egeland, Torstein; Lie, John; Persson, Ulla; Raymond, Joanne & Müller, Carlheinz (2004). Donor and liability insurance of donor registries, donor centers, and collection centers - recommendations. Bone Marrow Transplantation. ISSN 0268-3369. 33, p. 467–470.
• Bakken, Ruth; Van walraven, Anne-marie & Egeland, Torstein (2004). Donor commitment and patient needs. Bone Marrow Transplantation. ISSN 0268-3369. 33, p. 225–230.
• Heldal, Dag; Brinch, Lorentz; Tjønnfjord, Geir Erland; Solheim, Bjarte G.; Egeland, Torstein & Albrechtsen, Dagfinn [Show all 8 contributors for this article] (2003). Fewer relapses and increased chronic GVHD in patients transplanted with blood stem cells: a 5-years follow-up in a single centre study. Bone Marrow Transplantation. ISSN 0268-3369. 32, p. 257–264.
• Rosenmayr, Agathe; Hartwell, Linda & Egeland, Torstein (2003). Informed consent - suggested procedures for informed consent for unrelated haematopoietic stem cell donors at various stages of recruitment, donor evaluation, and donor workup. Bone Marrow Transplantation. ISSN 0268-3369. 31, p. 539–545.
• Egeland, Torstein (2000). European bone marrow donor registries - collaboration and individualism. In Ikeda, Y; Hata, Jun-ichi; Koyasu, S & Hattori, Y (Ed.), Cell Therapy. Springer-Verlag Tokyo Inc.. p. 209–221. Show summary

  The first registry of HLA-typed volunteer bone marrow donors made available for patients residing abroad was The Anthony Nolan Bone Marrow Trust founded in 1974 in London, England. Several years passed before other countries established registries. Later, due to the growing number of donors and need to facilitate donor search processes and tracking, the European Bone Marrow Transplantation Group (EBMT) took the initiative to established Bone Marrow Donors Worldwide (BMDW), and BMDW was generated in 1988 in Leiden, The Netherlands, under the auspices of the Europdonor Foundation. As of November 25, 1998, there are 5.4 mill. donors in BMDW from 59 registries and cord blood banks in 34 countries. 2.1 mill. donors, of whom 39% are AB and DR typed, are from 43 registries and cord blood banks in 25 European countries. In Europe, search processes, donor activation and confirmatory typing requests take place either through telematic systems (EDS developed by France Greffe de Moelle in Paris, France, or EMDIS developed by registries in England, France and Germany) or by direct com-munication. The high number of individual registries and multiple transplant centers across Europe underlines the need for a common telematic system. Today, several registries have to be addressed in a unique way to order certain services, some services may not be available, and reporting modes vary. Individual policies, varying resources, and national regulations make it a great challenge to get registries and transplant centers into a common system. On the other hand, the current "open" system allows high degree of flexibility and individual service which for instance may ease final donor workup and (re)transplantation planning in complicated or urgent settings.

• Steen, Rita; Tønnfjord, Geir E.; Groseth, Lill-Anny & Egeland, Torstein (2000). Characteristics of haematopoietic progenitor cells related to CD34 epitope class expression. European Journal of Haematology. ISSN 0902-4441. 64, p. 245–251. Show summary

  Haemopoietic progenitor cells (HPCs) express the CD34 molecule, a heavily glycosylated transmembrane protein which display three main classes of epitopes. The number of epitope class III+ HPCs is higher than class I+ and II+ HPCs. The aim of this study was to characterise CD34III+ and CD34II+ HPCs. The subsets were studied for coexpression of activation-, lineage-, and adhesion-associated molecules, clonogenic ability, and morphological features. Compared to CD34II+ HPCs, CD34III+ HPCs were enriched for CFU-GM and BFU-E and cells coexpressing CD13, CD33 cells, c-kit, and trans-ferrin receptor (CD71). The CD34III+/II- cell subset uniformly displayed CD13 and CD33, a high clonogenic capacity, and morphological characteristics of promyelocytes and myelocytes. The data show that CD34 class III epitopes are more broadly distributed on HPCs than class II epitopes and that lack of class II epitope expression is mainly confined to myeloid progenitor cells. Lack of the sugar-associated class II epitopes may be due to enzymatic degradation or downregulation prior to loss of class III epitopes during late HPC differentiation. In addition, CD34III+/II- cells render a high proliferative potential.

• Heldal, Dag; Tjønnfjord, Geir Erland; Brinch, Lorentz; Albrechtsen, Dagfinn; Egeland, Torstein & Steen, Rikke L. [Show all 8 contributors for this article] (2000). A randomised study of allogeneic transplantation with stem cells from blood or bone marrow. Bone Marrow Transplantation. ISSN 0268-3369. 25, p. 1129–1136.
• Steen, Rita & Egeland, Torstein (1998). CD34 molecule epitope distribution on cells of haematopoietic origin. Leukemia and Lymphoma. ISSN 1042-8194. 30, p. 23–30.
• Wagemaker, Gerard; Hartong, S.C.C.; Neelis, Karen J.; Egeland, Torstein & Wognum, Albert W. (1998). In vivo expansion of hematopoietic stem cells. Stem Cells. ISSN 1066-5099. 16(Suppl 1), p. 185–191.
• Egeland, Torstein (1998). The CD34 molecule and hematopoietic studies - a challenge in clinical medicine. Vox Sanguinis. ISSN 0042-9007. 74(Suppl 1), p. 467–468.
• Tjønnfjord, Geir Erland; Steen, Rita; Veiby, Ole-Petter & Egeland, Torstein (1996). Lineage commitment of CD34+ human hematopoietic progenitor cells. Experimental Hematology. ISSN 0301-472X. 24, p. 875–882.
• Steen, Rita; Tjønnfjord, Geir Erland; Gaudernack, Gustav & Egeland, Torstein (1996). Differences in the distribution of CD34 epitopes on normal haematopoietic progenitor and leukaemic blast cells. British Journal of Haematology. ISSN 0007-1048. 94, p. 597–605.
• Lehne, Gustav; de Angelis, Paula; Clausen, Ole Petter Fraas; Egeland, Torstein; Tsuruo, Takashi & Rugstad, Hans Erik (1995). Binding diversity of antibodies against external and internal epitopes of the multidrug resistance gene product P-glycoprotein. Cytometry. ISSN 0196-4763. 20, p. 228–237. Show summary

  P-glycoprotein (Pgp) is a trans-membraneous protein that is associated with multidrug resistance (MDR) in human cancer, including hepatocellular carcinomas and leukemias. There is no consensus regarding methods of choice for analysis of Pgp expression, and development of reliable analytical methods is now essential. We have studied the the Pgp expression in human hepatoma and leukemia cell lines using flow cytometry. The aim of the study was to compare binding properties of anti-Pgp antibodies reacting with surface (MRK16, UIC2) and cytoplasmic (C219, JSB-1) epitopes to assess which antibody performed best with respect to fluorescence discrimination. By histogram subtraction the fractions of resistant human hepatoma cells positive for Pgp were 99% (MRK16), 97% (UIC2), 77% (JSB-1), and 51% (C219), demonstrating variations in antibody reactivity. The resolution in detecting decreasing levels of Pgp in hepatoma cells was superior for the externally binding antibodies, showing that there is a correlation between antibody reactivity and fluorescence discrimination. Similar results were obtained for parental and resistant KG1a human leukemia cell lines. The Pgp epitopes remained reactive to the anti-Pgp MAbs after methanol fixation and cryopreservation. By dual parameter flow cytometry it was shown that Pgp expression in viable cells may be assessed together with uptake of epirubicin, which was low in cells expressing high levels of Pgp and vice versa. In conclusion, all tested antibodies proved useful for flow cytometric detection of high levels of Pgp, but the externally binding ones were superior in detection of low and variable levels of Pgp.

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• Grønvold, Bjørn Christer Linder; Ali, M.M.; Remberger, M.; Mattsson, J.; Egeland, Torstein & Lundin, Katrin [Show all 13 contributors for this article] (2020). HLA-DPB1 mismatch reduce relapse and improve survival in T-cell replete unrelated donor allogeneic stem cell transplantation. Bone Marrow Transplantation. ISSN 0268-3369. 55(8), p. 1658–1661. doi: 10.1038/s41409-020-0827-3.
• Egeland, Torstein; Angelsen, Arild; Haug, Ruth; Henriksen, Jan-Olav; Lea, Tor Erling & Saugstad, Ola Didrik (2015). T. Egeland og medarbeidere svarer. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 135(22), p. 2020–2021. doi: 10.4045/tidsskr.15.1185.
• Egeland, Torstein; Angelsen, Arild; Haug, Ruth; Henriksen, Jan-Olav; Lea, Tor Erling & Saugstad, Ola Didrik (2015). T. Egeland og medarbeidere svarer. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 135(22), p. 2021–2022. doi: 10.4045/tidsskr.15.1230.
• Angelsen, Arild; Egeland, Torstein; Haug, Ruth; Henriksen, Jan-Olav; Lea, Tor Erling & Saugstad, Ola Didrik (2014). De ME-syke fortjener seriøs forskning. Aftenposten (morgenutg. : trykt utg.). ISSN 0804-3116.
• Flote, Vidar Gordon; Frydenberg, Hanne; Ursin, Giske; Wilsgaard, Tom; Iversen, Anne June & Ellison, Peter [Show all 10 contributors for this article] (2013). High-density lipoprotein cholesterol is associated with mammographic density in premenopausal women.
• Szodoray, Peter; Nakken, Britt; Osnes, Liv T. N.; Naper, Christian; Vaage, John Torgils & Egeland, Torstein (2012). IMMUNE REGULATORY EFFECTS OF HEMATOPOIETIC STEM CELL TRANSPLANTATION IN AUTOIMMUNE DISEASES. Cytometry. ISSN 0196-4763. 82B(6), p. 379–380.
• King, RJ; Schmidt, AH; Costeas, P & Egeland, Torstein (2012). Donors as research subjects: a challenge. Bone Marrow Transplantation. ISSN 0268-3369. 47(4), p. 605–606. doi: 10.1038/bmt.2011.127.
• Brinch, Lorentz; Fløisand, Yngvar; Tjønnfjord, Geir Erland; Gedde-Dahl, Thobias; Heldal, Dag & Holme, Pål Andre [Show all 7 contributors for this article] (2009). Allogeneic blood stem cell transplants for AML using the Bu4Cy2 regimen in AML: long term experience. Bone Marrow Transplantation. ISSN 0268-3369. 43, p. S98–S98.
• Heldal, Dag; Tjønnfjord, Geir Erland; Brinch, Lorentz; Albrechtsen, Dagfinn; Egeland, Torstein & Steen, Rikke L. [Show all 8 contributors for this article] (2000). A randomised study of allogeneic transplantation with stem cells from blood or bone marrow.

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