Projects

Read more about the groups projects below.

Mental Intervention and Nicotinamide Riboside supplementation in Long COVID (MINIRICO)
MINIRICO is a 2 x 2 factorial randomised control trial on the efficacy and safety of a mental intervention program vs. usual care and nicotinamide riboside (NR) vs. placebo for improving health-related quality of life in the post-COVID-19 condition. A total of n=310 participants are to be included. Data acquisition is expected completed in 2025. MINIRICO is currently including participants.
Short-term Behavioral Intervention for Post-COVID-19 Condition (SIPCOV)
SIPCOV is a pragmatic randomised controlled trial on the efficacy and safety of a short-time outpatient-based rehabilitation program as compared to usual care in the post-COVID-19 condition. A total of n=310 participants has been included.
Long-Term Effects of COVID-19 in Adolescents (LoTECA)
LoTECA is a prospective observational cohort study on the long-term effects of COVID-19 in non-hospitalised adolescents and young adult (n=517). The assessments include comprehensive symptom scores, deep immune cell phenotyping, blood transcriptomics, neurocognitive tests and functional brain MRI. The project entails comprehensive prediction analyses as well as cross-sectional assessments across groups of post-COVID-19 condition sufferers, recovered patients and healthy controls.
COVID-19 in hospitalised Norwegian children – risk factors, outcomes and immunology.
This is an observational, multicentre clinical study lead by PAEDIA researchers on children with acute COVID-19 admitted to Norwegian Paediatric hospital departments. Data include a wide range of clinical variables as well as biomarkers and questionnaire results.
Chronic Fatigue Syndrome following acute Epstein-Barr virus infections in Adolescents (CEBA).
CEBA was a prospective observational cohort study on the long-term effects of acute Epstein-Barr virus infection in adolescents, with particular emphasis on the development of post-infective fatigue syndrome (PIFS) (n=270). The assessments included comprehensive symptom scores, deep immune cell phenotyping, neurocognitive tests, and neuroendocrine assays. The project entails comprehensive prediction analyses as well as cross-sectional assessments across groups of PIFS sufferers, recovered patients and healthy controls.
Disease mechanisms in adolescent CFS/ME: an integrated, translational approach (NorCAPITAL).
NorCAPITAL was a combined observational study and a randomised controlled trial of clonidine vs. placebo for adolescent CFS/ME (n=120) (the RCT part was conducted at a different location). The assessments in the observational part included comprehensive clinical phenotyping, autonomic and neuroendocrine assessments, blood transcriptomics, and functional brain MRI.
Disease burden and economic impact of respiratory syncytial virus in Norway.
This is an epidemiological register-based study conducted in close collaboration with the Norwegian Institute of Public Health on the burden and economic impact of RSV infections.
Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing (INSTAR).
The INSTAR study is a multi-centre randomized controlled trial of dexamethasone vs. placebo for wheezing episodes following rhinovirus infection; the study is led by St. Olav’s Hospital, Trondheim.
Antibiotics, Microbiology and Immunology in Children with Chronic wet Cough (AMIC).
The AMIC study is a multi-centre randomized controlled trial of amoxicillin vs. placebo for chronic wet cough; the study is led by Stavanger University Hospital.
Music Therapy in Hospital-at-home with children in palliative treatment.
This is an exploratory intervention trial on personalized music therapy for children in hospital-at-home receiving palliative care.
Health literacy for young individuals: Its value for empowerment and successful transition (HI-FIVE).
HI-FIVE is a qualitative research project conducted as ‘Action research’ and primarily focusing on the transition program (from paediatric to adult medical care) within the clinical department.
Quality of neonatal cardiopulmonary resuscitation (INSPIRE-D).
INSPIRE-D is an observational study were real-life neonatal cardiopulmonary resuscitation episodes are videorecorded and subsequently analysed.
Inflammatory bowel disease in children and adolescents (IBSEN-3).
This is the paediatric arm of the large IBSEN-3 research program, led by the Dept. of Gastroenterology and entailing observational and translational research projects on inflammatory bowel disease.
Epigenetic modifications of key genes in placenta, fetal growth and diabetes risk.
This project is part of ‘STORK Grorudalen’: A comprehensive research program on risk factors for non-communicable diseases in a population based multi-ethnic cohort of 823 families, led by the Institute of Health and Society at the University of Oslo.
Predictive value of cardiac markers in children with heart murmurs (CAMUS).
CAMUS is an observational study of n=500 children with spontaneously discovered heart murmurs at the family doctor/health care centre, and n=125 children with a well-defined congenital cardiac abnormality in need of surgical or catheter-based correction. The overarching aim is to establish the predictive value of cardiac markers in children with heart murmurs., thereby avoiding a large amount of unnecessary comprehensive cardiac examinations in children with normal hearts. Assessments in the project includes symptom charting, clinical investigations, assays of blood cardiac markers, ECG, oximetry, and comprehensive echocardiography.
Challenging the paradigm of autism as primarily heritable: The impact of socio-demographic factors on autism-diagnosis in a clinical sample.
This is an epidemological study on childhood autism, using both health records and register-based data.

Published Jan. 18, 2024 11:33 AM - Last modified Jan. 18, 2024 11:33 AM