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Adjudication committee
- First opponent: Professor Suzanne E. Geerlings, Internal Medicine, Amsterdam University Medical Center, The Netherlands
- Second opponent: Professor Franck Bruyere, University Hospital of Tours, France
- Third member and chair of the evaluation committee: Professor Tone Tønjum, Institute of Clinical Medicine, University of Oslo
Chair of defence
Professor II Nils Einar Kløw, Institute of Clinical Medicine, University of Oslo
Summary
Health care associated urinary tract infections (HAUTI) in urology departments can be related to the interventions that involve the urinary tract. HAUTIs can become complex and hinder the recovery of patients following their treatments. A further complexity arises from antibiotic resistance that hinders both the prevention (prophylaxis) and treatment of HAUTIs. This can become a prominent problem in patients who develop severe HAUTIs such as urosepsis. In these patient’s antibiotic resistance can cause failure of empirical treatment that can increase the likelihood of morbidity and mortality.
In this thesis data from a global surveillance study of infections in urology departments was used to determine the prevalence of HAUTIs and their antibiotic resistance. The thesis consists of five published studies and one in peer review. Condition (cystitis, pyelonephritis and urosepsis) specific surveillance data utilized with appropriate analytical methods can improve empirical antibiotic selection.
Additional information
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