Digital Public Defence: Uyen Pham

MD Uyen Pham at Institute of Clinical Medicine will be defending the thesis Neuropsychiatric Aspects of Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson’s Disease for the degree of PhD (Philosophiae Doctor).

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The public defence will be held as a video conference over Zoom.

The defence will follow regular procedure as far as possible, hence it will be open to the public and the audience can ask ex auditorio questions when invited to do so.

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Due to copyright reasons, an electronic copy of the thesis must be ordered from the faculty. In order for the faculty to have time to process the order, it must be received by the faculty no later than 2 days prior to the public defence. Orders received later than 2 days before the defence will not be processed. Inquiries regarding the thesis after the public defence must be addressed to the candidate.

Digital Trial Lecture - time and place

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Adjudication committee

  • First opponent: Professor Poul Videbech, University of Copenhagen, Denmark
  • Second opponent: Chief Physician Anette Storstein, Haukeland University Hospital, Bergen
  • Third member and chair of the evaluation committee: Associate Professor Elfrida H. Kvarstein, Institute of Clinical Medicine, University of Oslo

Chair of defence

Professor Jan Helge Solbakk, Institute of Health and Society, University of Oslo

Principal Supervisor

Professor II Mathias Toft, Institute of Clinical Medicine, University of Oslo

Summary

Parkinson's disease (PD) is a chronic neurodegenerative disorder. Subthalamic nucleus deep brain stimulation (STN-DBS) is an effective treatment option for motor symptoms in advanced PD.

The main goals of this thesis were to study the personality characteristics of PD patients undergoing STN-DBS and to investigate the impact of STN-DBS on personality. Further, we sought to explore the effect of STN-DBS on self-perceived executive functioning in daily life.

The findings showed that PD patients who underwent STN-DBS had higher baseline-level of impulsivity. The results from the study indicated that STN-DBS affected PD patients’ personality by increasing certain aspects of impulsivity. Self-perceived executive functioning in daily life improved following STN-DBS. 

This study has contributed to enhancing the knowledge of the personality profile of PD patients selected for STN-DBS and the impact of STN-DBS on PD patients’ personality, and on self-perceived executive functioning in daily life.

Additional information

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Published Mar. 12, 2021 11:00 AM - Last modified Mar. 29, 2021 12:36 PM