Digital Public Defence: Rishav Koirala

MD Rishav Koirala at Institute of Clinical Medicine will be defending the thesis “Exploring outcome of trauma in terms of mental illnesses and inflammatory markers in a clinical population in Nepal” for the degree of PhD (Philosophiae Doctor).

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The public defence will be held as a video conference over Zoom.

The defence will follow regular procedure as far as possible, hence it will be open to the public and the audience can ask ex auditorio questions when invited to do so.

Click here to participate in the public defence

Download Zoom here

Due to copyright issues, an electronic copy of the thesis must be ordered from the faculty. For the faculty to have time to process the order, the order must be received by the faculty at the latest 2 days before the public defence. Orders received later than 2 days before the defence will not be processed. After the public defence, please address any inquiries regarding the thesis to the candidate.

Digital Trial Lecture – time and place

See Digital Trial Lecture.

Adjudication committee

  • First opponent: Research Associate Professor Jessica Carlsson  Lohmann, University of Copenhagen, Denmark
  • Second opponent: Associate Professor Sofie Bäärnhilem, Transkulturellt Centrum, Region Stockholm, Sweden
  • Third member and chair of the evaluation committee: Associate Professor Nils Eiel Steen, University of Oslo

Chair of the Defence

Professor Lars Mehlum, University of Oslo

Principal Supervisor

Associate Professor Suraj Thapa, University of Oslo

Summary

Traumatic experiences can cause several kinds of mental disorders such as post-traumatic stress disorder( PTSD), Complex PTSD (CPTSD), depression and other disorders. These problems have seen to impact quality of life (QOL). Moreover, trauma and trauma related disorders can also affect inflammatory markers such as cytokines.

Despite the high prevalence and long-term impact of trauma, there is a lack of awareness and proper management of trauma related mental disorders, especially in developing countries. Studies related to trauma is also rare in this part of world. Newer diagnostic entity such as CPTSD is also very less studied and the search for biological markers for trauma is ongoing.

We studied associated mental disorders, cytokines, QOL and sociodemographic profile in a trauma-affected help-seeking population coming to a tertiary hospital in Nepal. High rates of PTSD, CPTSD, depression and anxiety were seen. The CPTSD patients had lower QOL.  The increased levels of cytokines IL-6  and IL1-b were seen in trauma-affected people and PTSD patients, respectively.

The current work has contributed to understanding the impact of trauma in South Asian population.

Additional information

Contact the research support staff.

Published Oct. 17, 2022 9:37 AM - Last modified Oct. 27, 2022 4:28 PM