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Due to copyright issues, an electronic copy of the thesis must be ordered from the faculty. For the faculty to have time to process the order, the order must be received by the faculty at the latest 2 days before the public defence. Orders received later than 2 days before the defence will not be processed. After the public defence, please address any inquiries regarding the thesis to the candidate.
Trial Lecture – time and place
See Trial Lecture.
Adjudication committee
- First opponent: Professor Leendert Trouw, University of Leiden, Netherlands
- Second opponent: Visiting Professor Claire Harris, Newcastle University, UK
- Third member and chair of the evaluation committee: Professor Marit Inngjerdingen, University of Oslo
Chair of the Defence
Associate Professor Carola Elisabeth Henriksson, University of Oslo
Principal Supervisor
Professor II Tom Eirik Mollnes, University of Oslo
Summary
In this study, Beatrice Fageräng and others have examined the various parts of the blood innate immune system and how they work together to protect us from infection and induce inflammation. By gaining a better understanding of these responses, they aim to improve our knowledge of the innate immune system's reactions and develop new treatments for diseases, as well as enhance our understanding of existing treatments.
This research utilized a model called the «lepirudin whole blood model», which allows for the study of immune components in blood without causing clotting. In the first project, they investigated the specific roles of different cells in biomarker release and developed a method for studying these cells. In the second project, they used the whole blood model to explore the immune system's response to fungi. In the third project, they examined how cancer therapy, specifically stem cell transplantation, affected the innate immune system response.
Collectively, this research offers fresh insights into how the immune system operates in various scenarios and holds promise for assisting a wide range of patients with various health conditions.
Additional information
Contact the research support staff.