Due to copyright issues, an electronic copy of the thesis must be ordered from the faculty. For the faculty to have time to process the order, the order must be received by the faculty at the latest 2 days before the public defence. Orders received later than 2 days before the defence will not be processed. After the public defence, please address any inquiries regarding the thesis to the candidate.
Trial Lecture – time and place
See Trial Lecture.
Adjudication committee
- First opponent: Consultant Amarnath Bhide, St. George’s University Hospital, UK
- Second opponent: Professor II Ingvild Bruun Mikalsen, UiB - University of Bergen
- Third member and chair of the evaluation committee: Professor II Anna Kristina Bjerre, University of Oslo
Chair of the Defence
Professor II Ole Henning Skjønsberg, University of Oslo
Principal Supervisor
Professor Emeritus Guttorm Nils Haugen, University of Oslo
Summary
Reduced lung function in infancy is associated with lung disease, and decreased lung function in later life. Little is known concerning the relationship between fetal size and growth, or specific measures of fetal lungs and their blood circulation, and lung function after birth.
This study aimed to explore the associations between fetal size and growth, as well as measures related to lung size and pulmonary circulation, and lung function in infants from the general population.
In a sub cohort from the PreventADALL study ultrasound measures from 457 fetuses at 30 gestational weeks were used to explore their associations with lung function at 3 months of infant age obtained by tidal flow-volume loops, available in 257 of these participants.
The key observations were that fetal size, fetal weight increase in the third trimester, or blood flow measures in fetal umbilical and middle cerebral artery were not associated with infant lung function. Similarly, no such associations were detected for fetal lung volume, thoracic circumference, third trimester thoracic growth rate, or blood flow measures in the fetal pulmonary artery.
Additional information
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