About the project
In primary health care there is a lack of diagnostic tools for IBD. Diagnostic delay is therefore common in paediatric IBD. This results in delayed physical growth, delayed skeletal maturation, and may lead to impaired psychosocial development.
Currently, fecal calprotectin currently is the test with highest sensitivity, but fecal samples can be difficult to obtain, especially for children and adolescents. For CRP, it is a challenge that the majority of patients with IBD do not mount a CRP response.
A blood-based biomarker is therefore warranted in paediatric IBD.
Aim of research
This is a NORDTREAT project. The main aim is to identify and validate a diagnostic protein signature of paediatric IBD in blood. This signature could be used to guide decisions on referral to endoscopy and facilitate early diagnosis of IBD.