About the project
While co-cultures of pancreatic cancer cells and pancreatic stellate cells (cfr. Project 1) are by far more representative of the in vivo situation, they still do not represent the full repertoire of extracellular components and other structures in the tumour microenvironment.
In this project, a model based on the culturing of thin slices (ca. 300 micron thick) of human pancreatic cancer tissue, is optimized and used for testing of various drugs.
Photo: "Flow chart" - Misra, Sougat. et al. Sci. Rep. 2019;9:2133
Collaborators
- Mikael Björnstedt, Dept of Pathology, Karolinska Institute, Sweden
- Carlos Fernandez Moro, Dept of Pathology, Karolinska Institute, Sweden
Funding
- University of Oslo
Study period
- 2018 - ongoing