Trial Lecture - time and place
See Trial Lecture.
Adjudication committee
- First opponent: Principal Investigator and Group Leader Caroline Heckman, University of Helsinki
- Second opponent: Professor Elling Ulvestad, University og Bergen
- Third member of the adjudication committee: Professor Farrukh Chaudhry, Univerity of Oslo
Chair of the Defence
Professor Britt Nakstad, University of Oslo
Principal Supervisor
Professor Vegard Bruun Bratholm Wyller, University of Oslo
Summary
Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is an important cause of disability among adolescents whereas molecular mechanism underlying CFS/ME pathophysiology is unknown.
By using molecular and bioinformatics methods, the current thesis investigated the association of the variants 5-HTTLPR and rs25531 of the serotonin transporter gene (5-HTT /SLC6A4) in disease development over time as well the deregulation of global gene expression and immune genes network in CFS/ME that could be associated with disease markers.
Additional information
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