PURPOSE: The repeated use of prescription opioids may lead to serious side effects. It is therefore important to examine factors associated with such repeated use. The aim of this study was to investigate the association between the maternal use of prescription opioids and their use by offspring of these mothers.
Publikasjoner - Side 20
Naltrexone is an opioid receptor antagonist that blocks the reinforcing effects of opioids and reduces alcohol consumption and craving. It has no abuse potential, mild and transient side effects, and thus appears an ideal pharmacotherapy for opioid dependence.
INTRODUCTION: Carisoprodol, a frequently used muscle relaxant, can cause potentially fatal intoxications. Conversion to its active metabolite meprobamate is almost solely mediated by cytochrome P450 2C19 (CYP2C19), and mutations in this enzyme could have significant effects on serum concentrations. The objective of this study was to investigate the role of CYP2C19 genetics in mortalities due to carisoprodol intoxication.
Background: The highly prevalent comorbidity of substance use disorders and psychiatric disorders represents challenges concerning diagnosis and treatment in acute psychiatric wards.
Baklofen er en GABAB-agonist uten kjent misbrukspotensial som er undersøkt ved alkoholrelaterte tilstander Dokumentasjonen for bruk ved alkoholabstinenser er utilstrekkelig Baklofen kan være et alternativ til disulfiram eller akamprosat som forebyggende behandling mot tilbakefall ved alkoholavhengighet.
BACKGROUND: Although opioid maintenance treatment (OMT) has been found to reduce crime, less is known about its associations with violent crime. This study investigates changes in violent crime convictions prior to, during, and after OMT, and examines the relationship between violent crime convictions prior to OMT with the risk of violent and non-violent crime convictions during treatment.
Bakgrunn. Ulike benzodiazepiner har prinsipielt samme virkningsmekanisme og skiller seg hovedsakelig fra hverandre ved forskjeller i farmakokinetikk. Det er ikke farmakologisk grunnlag for å bruke mer enn ett benzodiazepin til samme pasient. Formålet med undersøkelsen var å studere forekomst av samtidig bruk av ulike benzodiazepiner i Norge.
Opioid switching to methadone: a pharmacoepidemiological study from a national prescription database
BACKGROUND: Opioid switching to methadone is reported frequently to improve pain control in patients with an unacceptable balance between pain control and side effects during treatment with first line opioids, but carries a risk of drug accumulation and respiratory depression. To justify this risk it is required that less risky treatments are tried beforehand and that a sufficiently large proportion of patients experience a long-lasting improvement in pain control.
PURPOSE: To examine whether socioeconomic factors influence adherence to alendronate drug treatment among incident users in Norway during 2005-2009.
AIMS: This study investigates changes in criminal involvement among patients in opioid maintenance treatment (OMT) over a 7-year period prior to, during and after treatment, particularly in relation to differences in treatment engagement.
OBJECTIVE: Although depression is common among incurable cancer patients, the prescription prevalence of antidepressants (ADs) to these patients is largely unknown. Aims were to examine the prescription prevalence of ADs in the last year of life in a 2-year national cancer death cohort and to examine its associations with sociodemographic and medical variables.
AIMS: To investigate whether exposure to methadone affects the risk of motor vehicle accident with personal injury.
ABSTRACT: Use of amphetamine and methamphetamine is widespread in the general population and common among patients with psychiatric disorders. Amphetamines may induce symptoms of psychosis very similar to those of acute schizophrenia spectrum psychosis.
Carisoprodol, a centrally acting muscle relaxant indicated for acute lower back pain, has been available in Europe and the United States since 1959.
En oversikt over litteraturen aktuell for LAR i 2011.
Statusrapporten for 2011 er nå ferdig og kan lastes ned.
Background: Reduced criminal activity is an important outcome for opioid maintenance treatment (OMT).
The aim of this study was to assess possible differences in treatment organisation, practices and outcomes between 14 regional centres within the Norwegian Opioid Maintenance Treatment programme, which were subject to the same government standards.
The aim of the present study was to describe aspects of prescription of antidepresant drug therapy among patients on OMT.
The aim of the study was to identify this co-occurrence as a reason for involuntary admission and if specific substance use-related diagnoses were associated with such admissions.