Børre Fevang

• Skudal, Hilde Kristin; Lorentzen, Åslaug Rudjord; Stenstad, Tore; Paulsen, Else Quist; Egeland, Jens & Fevang, Børre [Vis alle 13 forfattere av denne artikkelen] (2024). Clinical characteristics and factors affecting disease severity in hospitalized tick-borne encephalitis patients in Norway from 2018 to 2022. European Journal of Clinical Microbiology and Infectious Diseases. ISSN 0934-9723. doi: 10.1007/s10096-024-04855-2.
• Yang, Mingyi; Kaarbø, Mari; Myhre, Vegard; Reims, HM; Karlsen, TH & Wang, Junbai [Vis alle 13 forfattere av denne artikkelen] (2024). Altered Genome-Wide DNA Methylation in the Duodenum of Common Variable Immunodeficiency Patients. Journal of Clinical Immunology. ISSN 0271-9142. 44(6). doi: 10.1007/s10875-024-01726-5.
• De Bortoli, Alessandro; Nordøy, Ingvild; Connelly, James Patrick; Viermyr, Hans-Kittil; Bjerkreim, Randi Haukaas & Broch, Kaspar [Vis alle 15 forfattere av denne artikkelen] (2024). Diagnostics, treatment and outcomes of cardiac sarcoidosis in a Norwegian cohort. International Journal of Cardiology. ISSN 0167-5273. 400. doi: 10.1016/j.ijcard.2024.131809.
• Jørgensen, Silje Fjellgård; Macpherson, Magnhild Eide; Skarpengland, Tonje; Berge, Rolf Kristian; Fevang, Børre & Halvorsen, Bente [Vis alle 7 forfattere av denne artikkelen] (2023). Disturbed lipid profile in common variable immunodeficiency – a pathogenic loop of inflammation and metabolic disturbances. Frontiers in Immunology. ISSN 1664-3224. 14. doi: 10.3389/fimmu.2023.1199727. Fulltekst i vitenarkiv
• Andersen, Ina Marie; Reims, Henrik Mikael; Grzyb, Krzysztof; Fevang, Børre; Melum, Espen & Aukrust, Pål [Vis alle 10 forfattere av denne artikkelen] (2023). Long-term survival after liver transplantation in patients with common variable immunodeficiency. Liver transplantation. ISSN 1527-6465. 29(8), s. 894–899. doi: 10.1097/LVT.0000000000000130.
• Bintalib, Heba M.; van de Ven, Annick; Jacob, Joseph; Davidsen, Jesper Rømhild; Fevang, Børre & Hanitsch, Leif G. [Vis alle 13 forfattere av denne artikkelen] (2023). Diagnostic testing for interstitial lung disease in common variable immunodeficiency: a systematic review. Frontiers in Immunology. ISSN 1664-3224. 14. doi: 10.3389/fimmu.2023.1190235.
• Macpherson, Magnhild Eide; Skarpengland, Tonje; Hov, Johannes Espolin Roksund; Ranheim, Trine; Vestad, Beate & Dahl, Tuva Børresdatter [Vis alle 14 forfattere av denne artikkelen] (2023). Increased Plasma Levels of Triglyceride-Enriched Lipoproteins Associate with Systemic Inflammation, Lipopolysaccharides, and Gut Dysbiosis in Common Variable Immunodeficiency. Journal of Clinical Immunology. ISSN 0271-9142. 43, s. 1229–1240. doi: 10.1007/s10875-023-01475-x. Fulltekst i vitenarkiv
• Fevang, Børre (2023). Treatment of inflammatory complications in common variable immunodeficiency (CVID): current concepts and future perspectives. Expert Review of Clinical Immunology. ISSN 1744-666X. 19(6), s. 627–638. doi: 10.1080/1744666X.2023.2198208.
• Lévy, Romain; Gothe, Florian; Momenilandi, Mana; Magg, Thomas; Materna, Marie & Peters, Philipp [Vis alle 37 forfattere av denne artikkelen] (2022). Human CARMIL2 deficiency underlies a broader immunological and clinical phenotype than CD28 deficiency. Journal of Experimental Medicine (JEM). ISSN 0022-1007. 220(2). doi: 10.1084/jem.20220275.
• Kaarbø, Mari; Yang, Mingyi; Hov, Johannes Espolin Roksund; Holm, Kristian; Sousa, Mirta & Macpherson, Magnhild Eide [Vis alle 15 forfattere av denne artikkelen] (2022). Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses. Journal of Allergy and Clinical Immunology. ISSN 0091-6749. doi: 10.1016/j.jaci.2022.09.029. Fulltekst i vitenarkiv Vis sammendrag

  Background A substantial proportion of common variable immunodeficiency (CVID) patients has duodenal inflammation of largely unknown etiology. However, because of its histologic similarities with celiac disease, gluten sensitivity has been proposed as a potential mechanism. Objective We aimed to elucidate the role of the duodenal microenvironment in the pathogenesis of duodenal inflammation in CVID by investigating the transcriptional, proteomic, and microbial signatures of duodenal biopsy samples in CVID. Methods DNA, total RNA, and protein were isolated from snap-frozen pieces of duodenal biopsy samples from CVID (with and without duodenal inflammation), healthy controls, and patients with celiac disease (untreated). RNA sequencing, mass spectrometry–based proteomics, and 16S ribosomal DNA sequencing (bacteria) were then performed. Results CVID separated from controls in regulation of transcriptional response to lipopolysaccharide and cellular immune responses. These differences were independent of mucosal inflammation. Instead, CVID patients with duodenal inflammation displayed alterations in transcription of genes involved in response to viral infections. Four proteins were differently regulated between CVID patients and healthy controls—DBNL, TRMT11, GCHFR, and IGHA2—independent of duodenal inflammation. Despite similar histology, there were major differences in CVID with duodenal inflammation and celiac disease both at the RNA and protein level. No significant difference was observed in the bacterial gut microbial signature between CVID, celiac, and healthy controls. Conclusion Our findings suggest the existence of altered functions of the duodenal epithelium, particularly in response to lipopolysaccharide and viruses. The latter finding was related to duodenal inflammation, suggesting that viruses, not gluten sensitivity, could be related to duodenal inflammation in CVID. Key words CVID RNA sequencing proteomics microbiome gut microbiota microbiota gastrointestinal tract duodenum celiac disease Primary immunodeficiency IgA

• Granerud, Beathe Kiland; Ueland, Thor; Lind, Andreas; Søraas, Arne Vasli; Fevang, Børre & Steffensen, Anne Katrine [Vis alle 14 forfattere av denne artikkelen] (2022). Omicron Variant Generates a Higher and More Sustained Viral Load in Nasopharynx and Saliva Than the Delta Variant of SARS-CoV-2. Viruses. ISSN 1999-4915. 14(11). doi: 10.3390/v14112420. Fulltekst i vitenarkiv Vis sammendrag

  The Omicron variant of SARS-CoV-2 spreads more easily than earlier variants, possibly as a result of a higher viral load in the upper respiratory tract and oral cavity. Hence, we investigated whether the Omicron variant generates a higher viral load than that of the Delta variant in saliva and nasopharynx. Both specimens were collected from 52 Omicron and 17 Delta cases at two time points one week apart and analyzed by qRT-PCR. Viral load was measured as 10 log RNA genome copies per 1000 human cells according to the WHO reference standard. We found that Omicron cases carried a higher viral load and had more sustained viral shedding compared to the Delta cases, especially in the nasopharynx.

• Søraas, Arne Vasli; Grødeland, Gunnveig; Granerud, Beathe Kiland; Ueland, Thor; Lind, Andreas & Fevang, Børre [Vis alle 32 forfattere av denne artikkelen] (2022). Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity. Frontiers in Immunology. ISSN 1664-3224. 13:964525, s. 1–12. doi: 10.3389/fimmu.2022.964525. Fulltekst i vitenarkiv Vis sammendrag

  Background: Results showing that sera from double vaccinated individuals have minimal neutralizing activity against Omicron have been interpreted as indicating the need for a third vaccine dose for protection. However, there is little information about early immune responses to Omicron infection in double vaccinated individuals. Methods: We measured inflammatory mediators, antibodies to the SARS-CoV-2 spike and nucleocapsid proteins, and spike peptide-induced release of interferon gamma in whole blood in 51 double-vaccinated individuals infected with Omicron, in 14 infected with Delta, and in 18 healthy controls. The median time points for the first and second samples were 7 and 14 days after symptom onset, respectively. Findings: Infection with Omicron or Delta led to a rapid and similar increase in antibodies to the receptor-binding domain (RBD) of Omicron protein and spike peptide-induced interferon gamma in whole blood. Both the Omicron- and the Delta-infected patients had a mild and transient increase in inflammatory parameters. Interpretation: The results suggest that two vaccine doses are sufficient to mount a rapid and potent immune response upon infection in healthy individuals of with the Omicron variant.

• Fraz, Mai Sasaki Aanensen; Michelsen, Annika Elisabet; Moe, Natasha; Aaløkken, Trond Mogens; Macpherson, Magnhild Eide & Nordøy, Ingvild [Vis alle 12 forfattere av denne artikkelen] (2022). Raised Serum Markers of T Cell Activation and Exhaustion in Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency. Journal of Clinical Immunology. ISSN 0271-9142. s. 1–11. doi: 10.1007/s10875-022-01318-1. Fulltekst i vitenarkiv
• Tveita, Anders Aune; Murphy, Sarah Louise Mikalsen; Holter, Jan Cato; Kildal, Anders Benjamin; Michelsen, Annika Elisabet & Lerum, Tøri Vigeland [Vis alle 28 forfattere av denne artikkelen] (2022). High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19. Journal of Infectious Diseases. ISSN 0022-1899. 226(12), s. 2150–2160. doi: 10.1093/infdis/jiac313. Fulltekst i vitenarkiv
• Trøseid, Marius; Dahl, Tuva Børresdatter; Holter, Jan Cato; Kildal, Anders Benjamin; Murphy, Sarah Louise Mikalsen & Yang, Kuan [Vis alle 28 forfattere av denne artikkelen] (2022). Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies. Journal of Internal Medicine. ISSN 0954-6820. 292(5), s. 816–828. doi: 10.1111/joim.13549. Fulltekst i vitenarkiv
• Fevang, Børre; Wyller, Vegard Bruun Bratholm; Mollnes, Tom Eirik; Pedersen, Maria; Asprusten, Tarjei Tørre & Michelsen, Annika Elisabet [Vis alle 8 forfattere av denne artikkelen] (2021). Lasting Immunological Imprint of Primary Epstein-Barr Virus Infection With Associations to Chronic Low-Grade Inflammation and Fatigue. Frontiers in Immunology. ISSN 1664-3224. 12. doi: 10.3389/fimmu.2021.715102. Fulltekst i vitenarkiv
• Jørgensen, Silje Fjellgård; Buechner, Jochen; Myhre, Anders Eivind; Galteland, Eivind; Spetalen, Signe & Kulseth, Mari Ann [Vis alle 19 forfattere av denne artikkelen] (2021). A Nationwide Study of GATA2 Deficiency in Norway-the Majority of Patients Have Undergone Allo-HSCT. Journal of Clinical Immunology. ISSN 0271-9142. doi: 10.1007/s10875-021-01189-y. Fulltekst i vitenarkiv Vis sammendrag

  Purpose: GATA2 deficiency is a rare primary immunodeficiency that has become increasingly recognized due to improved molecular diagnostics and clinical awareness. The only cure for GATA2 deficiency is allogeneic hematopoietic stem cell transplantation (allo-HSCT). The inconsistency of genotype-phenotype correlations makes the decision regarding "who and when" to transplant challenging. Despite considerable morbidity and mortality, the reported proportion of patients with GATA2 deficiency that has undergone allo-HSCT is low (~ 35%). The purpose of this study was to explore if detailed clinical, genetic, and bone marrow characteristics could predict end-point outcome, i.e., death and allo-HSCT. Methods: All medical genetics departments in Norway were contacted to identify GATA2 deficient individuals. Clinical information, genetic variants, treatment, and outcome were subsequently retrieved from the patients' medical records. Results: Between 2013 and 2020, we identified 10 index cases or probands, four additional symptomatic patients, and no asymptomatic patients with germline GATA2 variants. These patients had a diverse clinical phenotype dominated by cytopenia (13/14), myeloid neoplasia (10/14), warts (8/14), and hearing loss (7/14). No valid genotype-phenotype correlations were found in our data set, and the phenotypes varied also within families. We found that 11/14 patients (79%), with known GATA2 deficiency, had already undergone allo-HSCT. In addition, one patient is awaiting allo-HSCT. The indications to perform allo-HSCT were myeloid neoplasia, disseminated viral infection, severe obliterating bronchiolitis, and/or HPV-associated in situ carcinoma. Two patients died, 8 months and 7 years after allo-HSCT, respectively. Conclusion: Our main conclusion is that the majority of patients with symptomatic GATA2 deficiency will need allo-HSCT, and a close surveillance of these patients is important to find the "optimal window" for allo-HSCT. We advocate a more offensive approach to allo-HSCT than previously described.

• Skarpengland, Tonje; Macpherson, Magnhild Eide; Hov, Johannes R.; Kong, Xiang Yi; Bohov, Pavol & Halvorsen, Bente [Vis alle 10 forfattere av denne artikkelen] (2021). Altered Plasma Fatty Acids Associate with Gut Microbial Composition in Common Variable Immunodeficiency. Journal of Clinical Immunology. ISSN 0271-9142. s. 1–12. doi: 10.1007/s10875-021-01146-9.
• Hustad, Nina Berger; Degerud, Hanna M; Hjelmerud, Ingrid; Fraz, Mai Sasaki Aanensen; Nordøy, Ingvild & Trøseid, Marius [Vis alle 9 forfattere av denne artikkelen] (2021). Real-World Experiences With Facilitated Subcutaneous Immunoglobulin Substitution in Patients With Hypogammaglobulinemia, Using a Three-Step Ramp-Up Schedule. Frontiers in Immunology. ISSN 1664-3224. 12, s. 1–7. doi: 10.3389/fimmu.2021.670547. Fulltekst i vitenarkiv
• Fraz, Mai Sasaki Aanensen; Moe, Natasha; Rootwelt-Revheim, Mona-Elisabeth; Stavrinou, Maria; Durheim, Michael & Nordøy, Ingvild [Vis alle 11 forfattere av denne artikkelen] (2021). Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency—Features of CT and 18F-FDG Positron Emission Tomography/CT in Clinically Progressive Disease. Frontiers in Immunology. ISSN 1664-3224. 11. doi: 10.3389/fimmu.2020.617985. Fulltekst i vitenarkiv
• van de Ven, Annick A J M; Alfaro, Tiago M; Robinson, Alexandra N.; Baumann, Ulrich; Bergeron, Anne & Burns, Siobhan O [Vis alle 22 forfattere av denne artikkelen] (2020). Managing Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency Disorders: e-GLILDnet International Clinicians Survey. Frontiers in Immunology. ISSN 1664-3224. 11. doi: 10.3389/fimmu.2020.606333.
• Nordøy, Ingvild; Fraz, Mai Sasaki Aanensen; Trøseid, Marius; Fevang, Børre & Aukrust, Pål (2020). Høyt serum-ferritin ikke kun uttrykk for leversvikt. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 140(8). doi: 10.4045/tidsskr.20.0376.
• Ueland, Thor; Heggelund, Lars; Lind, Andreas; Holten, Aleksander Rygh; Tonby, Kristian & Michelsen, Annika [Vis alle 26 forfattere av denne artikkelen] (2020). Elevated plasma sTIM-3 levels in patients with severe COVID-19. Journal of Allergy and Clinical Immunology. ISSN 0091-6749. 147(1), s. 92–98. doi: 10.1016/j.jaci.2020.09.007. Fulltekst i vitenarkiv
• Holter, Jan Cato; Pischke, Soeren; de Boer, Eline; Lind, Andreas; Jenum, Synne & Holten, Aleksander Rygh [Vis alle 32 forfattere av denne artikkelen] (2020). Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients . Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 117(40), s. 25018–25025. doi: 10.1073/pnas.2010540117. Fulltekst i vitenarkiv
• Macpherson, Magnhild Eide; Hov, Johannes Espolin Roksund; Ueland, Thor; Dahl, Tuva Børresdatter; Kummen, Martin & Otterdal, Kari [Vis alle 14 forfattere av denne artikkelen] (2020). Gut microbiota-dependent trimethylamine N-oxide associates with inflammation in common variable immunodeficiency. Frontiers in Immunology. ISSN 1664-3224. 11. doi: 10.3389/fimmu.2020.574500. Fulltekst i vitenarkiv
• Holmøy, Trygve; Fevang, Børre; Olsen, David Benee; Spigset, Olav & Bø, Lars (2019). Adverse events with fatal outcome associated with alemtuzumab treatment in multiple sclerosis. BMC Research Notes. ISSN 1756-0500. 12(1), s. 1–5. doi: 10.1186/s13104-019-4507-6. Fulltekst i vitenarkiv
• Macpherson, Magnhild Eide; Halvorsen, Bente; Yndestad, Arne; Ueland, Thor; Mollnes, Tom Eirik & Berge, Rolf Kristian [Vis alle 14 forfattere av denne artikkelen] (2019). Impaired HDL function amplifies systemic inflammation in common variable immunodeficiency. Scientific Reports. ISSN 2045-2322. 9:9427, s. 1–10. doi: 10.1038/s41598-019-45861-1. Fulltekst i vitenarkiv
• Jørgensen, Silje Fjellgård; Macpherson, Magnhild Eide; Bjørnetrø, Tonje; Holm, Kristian; Kummen, Martin & Rashidi, Azita [Vis alle 18 forfattere av denne artikkelen] (2019). Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency. Scientific Reports. ISSN 2045-2322. 9:167, s. 1–10. doi: 10.1038/s41598-018-35367-7. Fulltekst i vitenarkiv
• Jørgensen, Silje Fjellgård; Fevang, Børre & Aukrust, Pål (2018). Autoimmunity and Inflammation in CVID: a Possible Crosstalk between Immune Activation, Gut Microbiota, and Epigenetic Modifications. Journal of Clinical Immunology. ISSN 0271-9142. 39(1), s. 30–36. doi: 10.1007/s10875-018-0574-z.
• Trøseid, Marius; Nordøy, Ingvild; Fevang, Børre & Aukrust, Pål (2018). Anbud på hivlegemidler er ikke faglig begrunnet. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 138(20), s. 1–3. doi: 10.4045/tidsskr.18.0808.
• Otterdal, Kari; Berg, Åse; Michelsen, Annika; Patel, Sam; Tellevik, Marit Gjerde & Haanshuus, Christel Gill [Vis alle 10 forfattere av denne artikkelen] (2018). Soluble markers of neutrophil, T-cell and monocyte activation are associated with disease severity and parasitemia in falciparum malaria. BMC Infectious Diseases. ISSN 1471-2334. 18. doi: 10.1186/s12879-018-3593-8. Fulltekst i vitenarkiv Vis sammendrag

  BACKGROUND: The immune response during P. falciparum infection is a two-edged sword, involving dysregulation of the inflammatory responses with several types of immune cells participating. Here we examined T-cell, monocyte/macrophage and neutrophil activation during P. falciparum infection by using soluble activation markers for these leukocyte subsets. METHODS: In a prospective cross-sectional study clinical data and blood samples were collected from adults in Mozambique with P. falciparum infection, with (n = 70) and without (n = 61) co-infection with HIV-1, as well as HIV-infected patients with similar symptoms but without malaria (n = 58) and healthy controls (n = 52). Soluble (s)CD25, sCD14, sCD163 and myeloperoxidase (MPO) as markers for T-cell, monocyte/macrophage and neutrophil activation, respectively as well as CX3CL1, granzyme B and TIM-3 as markers of T-cell subsets and T-cell exhaustion, were analyzed. RESULTS: All patient groups had raised levels of activation markers compared with healthy controls. Levels of sCD25 and MPO increased gradually from patient with HIV only to patient with malaria only, with the highest levels in the HIV/malaria group. In the malaria group as a whole, MPO, sCD14 and in particular sCD25 were correlated with disease severity. sCD163, sCD25 and in particular MPO correlated with the degree of parasitemia as assessed by qPCR. Patients with falciparum malaria also had signs of T-cell subset activation (i.e. increased granzyme B and CX3CL1) and T-cell exhaustion as assessed by high levels of TIM-3 particularly in patients co-infected with HIV. CONCLUSION: Our data support a marked immune activation in falciparum malaria involving all major leukocyte subsets with particular enhanced activation of neutrophils and T-cells in patients co-infected with HIV. Our findings also support a link between immune activation and immune exhaustion during falciparum malaria, particularly in relation to T-cell responses in patients co-infected with HIV

• Holm, Kristine Lillebø; Syljuåsen, Randi G.; Hasvold, Grete; Alsøe, Lene; Nilsen, Hilde Loge & Ivanauskiene, Kristina [Vis alle 13 forfattere av denne artikkelen] (2017). TLR9 stimulation of B-cells induces transcription of p53 and prevents spontaneous and irradiation-induced cell death independent of DNA damage responses. Implications for Common variable immunodeficiency. PLOS ONE. ISSN 1932-6203. 12(10). doi: 10.1371/journal.pone.0185708. Fulltekst i vitenarkiv
• Taraldsrud, Eli; Fevang, Børre; Jørgensen, Silje Fjellgård; Moltu, Kristine; Hilden, Vera Irene & Tasken, Kjetil [Vis alle 9 forfattere av denne artikkelen] (2017). Defective IL-4 signaling in T cells defines severe common variable immunodeficiency. Journal of Autoimmunity. ISSN 0896-8411. 81, s. 110–119. doi: 10.1016/j.jaut.2017.04.004.
• Stuchly, Jan; Kanderova, Veronika; Vlkova, Marcela; Hermanova, Ivana; Slamova, Lucie & Pelak, Ondrej [Vis alle 16 forfattere av denne artikkelen] (2017). Common Variable Immunodeficiency patients with a phenotypic profile of immunosenescence present with thrombocytopenia. Scientific Reports. ISSN 2045-2322. 7. doi: 10.1038/srep39710.
• Taraldsrud, Eli; Aukrust, Pål; Jørgensen, Silje Fjellgård; Lingjærde, Ole Christian; Olweus, Johanna & Myklebust, June [Vis alle 7 forfattere av denne artikkelen] (2017). Patterns of constitutively phosphorylated kinases in B cells are associated with disease severity in common variable immunodeficiency. Clinical Immunology. ISSN 1521-6616. 175, s. 69–74. doi: 10.1016/j.clim.2016.11.014. Vis sammendrag

  Patients with common variable immunodeficiency (CVID) constitute a clinically and immunologically heterogeneous group characterized by B-cell dysfunction with hypogammaglobulinemia and defective immunoglobulin class switch of unknown etiology. Current classification systems are insufficient to achieve precise disease management. Characterization of signaling pathways essential for B-cell differentiation and class switch could provide new means to stratify patients. We evaluated constitutive and induced signaling by phospho-specific flow cytometry in 26 CVID patients and 18 healthy blood donors. Strong responses were induced both in CVID and healthy donor B cells upon activation. In contrast, constitutive phosphorylation levels of STAT3,-5,-6, Erk, PLC-γ and Syk were significantly increased in CVID B cells only. Hierarchical clustering revealed a subgroup of CVID patients with elevated constitutive phosphorylation of Syk and PLC-γ. All these patients had non-infectious complications, indicating that a distinct phosphorylation pattern of kinases in B cells identifies a clinically important subgroup of CVID patients.

• Stray-Pedersen, Asbjørg; Sorte, Hanne Sørmo; Samarakoon, Pubudu Saneth; Gambin, Tomasz; Chinn, Ivan K. & Akdemir, Zeynep H.C. [Vis alle 51 forfattere av denne artikkelen] (2016). Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders. Journal of Allergy and Clinical Immunology. ISSN 0091-6749. 139(1), s. 232–245. doi: 10.1016/j.jaci.2016.05.042.
• Falkenberg-Jensen, Benedicte ; Aaløkken, Trond Mogens & Fevang, Børre (2016). Atypiske mykobakterier og lady Windermere. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 136(14), s. 1227–1227. doi: 10.4045/tidsskr.16.0235.
• Sorte, Hanne Sørmo; Osnes, Liv T. N.; Fevang, Børre; Aukrust, Pål; Erichsen, Hans Christian & Backe, Paul Hoff [Vis alle 20 forfattere av denne artikkelen] (2016). A potential founder variant in CARMIL2/RLTPR in three Norwegian families with warts, molluscum contagiosum, and T-cell dysfunction. Molecular Genetics & Genomic Medicine. ISSN 2324-9269. 4(6), s. 604–616. doi: 10.1002/mgg3.237.
• Jørgensen, Silje Fjellgård; Reims, Henrik Mikael; Frydenlund, Didrik Søli; Holm, Kristian; Paulsen, Vemund & Michelsen, Annika [Vis alle 23 forfattere av denne artikkelen] (2016). A Cross-Sectional Study of the Prevalence of Gastrointestinal Symptoms and Pathology in Patients with Common Variable Immunodeficiency. American Journal of Gastroenterology. ISSN 0002-9270. 111(10), s. 1467–1475. doi: 10.1038/ajg.2016.329.
• Jørgensen, Silje Fjellgård; Trøseid, Marius; Kummen, Martin; Anmarkrud, Jarl Andreas; Michelsen, Annika & Osnes, Liv T. N. [Vis alle 21 forfattere av denne artikkelen] (2016). Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation. Mucosal Immunology. ISSN 1933-0219. doi: 10.1038/mi.2016.18.
• Elgizouli, Magdeldin; Lowe, David M.; Speckmann, Carsten; Schubert, Desirée; Hülsdünker, Jan & Eskandarian, Zoya [Vis alle 15 forfattere av denne artikkelen] (2016). Activating PI3Kδ mutations in a cohort of 669 patients with primary immunodeficiency. Clinical and Experimental Immunology. ISSN 0009-9104. 183(2), s. 221–229. doi: 10.1111/cei.12706.
• Indrevær, Randi Larsen; Moskaug, Jan Øivind; Paur, Ingvild; Bøhn, Siv Kjølsrud; Jørgensen, Silje Fjellgård & Blomhoff, Rune [Vis alle 9 forfattere av denne artikkelen] (2015). IRF4 is a critical gene in retinoic acid-mediated plasma cell formation and is deregulated in common variable immunodeficiency-derived B cells. Journal of Immunology. ISSN 0022-1767. 195(6), s. 2601–2611. doi: 10.4049/jimmunol.1500250.
• Li, Jin; Jørgensen, Silje Fjellgård; Maggadóttir, Sólrún Melkorka; Bakay, Marina; Warnatz, Klaus & Glessner, Joseph [Vis alle 39 forfattere av denne artikkelen] (2015). Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells. Nature Communications. ISSN 2041-1723. 6. doi: 10.1038/ncomms7804.
• Taraldsrud, Eli; Fevang, Børre; Aukrust, Pål; Beiske, Klaus; Fløisand, Yngvar & Frøland, Stig Sophus [Vis alle 8 forfattere av denne artikkelen] (2014). Common variable immunodeficiency revisited: Normal generation of naturally occurring dendritic cells that respond to Toll-like receptors 7 and 9. Clinical and Experimental Immunology. ISSN 0009-9104. 175(3), s. 439–448. doi: 10.1111/cei.12239.
• Gregersen, Stina; Holm, Are Martin; Fevang, Børre; Ueland, Thor; Sikkeland, Liv Ingunn Bjoner & Aaløkken, Trond Mogens [Vis alle 11 forfattere av denne artikkelen] (2013). Lung disease, T-cells and inflammation in common variable immunodeficiency disorders. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 73(6), s. 514–522. doi: 10.3109/00365513.2013.819523.
• Indrevær, Randi Larsen; Holm, Kristine Lillebø; Aukrust, Pål; Osnes, Liv T. N.; Naderi, Elin Hallan & Fevang, Børre [Vis alle 7 forfattere av denne artikkelen] (2013). Retinoic acid improves defective TLR9/RP105-induced immune responses in common variable immunodeficiency-derived B cells. Journal of Immunology. ISSN 0022-1767. 191(7), s. 3624–3633. doi: 10.4049/jimmunol.1300213.
• Smedbakken, Linda Merete; Halvorsen, Bente ; Daissormont, Isabelle; Ranheim, Trine; Michelsen, Annika & Skjelland, Mona [Vis alle 19 forfattere av denne artikkelen] (2012). Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis - Potential role in plaque stabilization. Atherosclerosis. ISSN 0021-9150. 224(1), s. 266–273. doi: 10.1016/j.atherosclerosis.2012.06.071.
• Gregersen, Stina; Aaløkken, TM; Mynarek, Georg; Fevang, Børre; Holm, Are Martin & Ueland, Thor [Vis alle 10 forfattere av denne artikkelen] (2010). Development of pulmonary abnormalities in patients with common variable immunodeficiency: associations with clinical and immunologic factors. Annals of Allergy, Asthma & Immunology. ISSN 1081-1206. 104(6), s. 503–510. doi: 10.1016/j.anai.2010.04.015.
• Damås, Jan Kristian; Landrø, Linn Aina Ysland; Fevang, Børre; Heggelund, Lars; Frøland, Stig Sophus & Aukrust, Pål (2009). Enhanced levels of the CCR7 ligands CCL19 and CCL21 in HIV infection: correlation with viral load, disease progression and response to highly active antiretroviral therapy. AIDS (London). ISSN 0269-9370. 23(1), s. 135–138. doi: 10.1097/QAD.0b013e32831cf595.
• Fevang, Børre; Yndestad, Arne; Damås, Jan Kristian; Bjerkeli, Vigdis; Ueland, Thor & Holm, Are Martin [Vis alle 9 forfattere av denne artikkelen] (2009). Chemokines and common variable immunodeficiency; possible contribution of the fractalkine system (CX3CL1/CX3CR1) to chronic inflammation. Clinical Immunology. ISSN 1521-6616. 130(2), s. 151–161. doi: 10.1016/j.clim.2008.09.002.
• Fevang, Børre; Yndestad, Arne; Damås, Jan Kristian; Halvorsen, Bente ; Holm, Are Martin & Beiske, K [Vis alle 8 forfattere av denne artikkelen] (2009). Chemokines and common variable immunodeficiency; possible contribution of CCL19, CCL21 and CCR7 to immune dysregulation. Clinical and Experimental Immunology. ISSN 0009-9104. 158(2), s. 237–245. doi: 10.1111/j.1365-2249.2009.04013.x.
• Landrø, Linn Aina Ysland; Damås, Jan Kristian; Halvorsen, Bente ; Fevang, Børre; Ueland, Thor & Otterdal, Kari [Vis alle 9 forfattere av denne artikkelen] (2009). CXCL16 in HIV infection - a link between inflammation and viral replication. European Journal of Clinical Investigation. ISSN 0014-2972. 39(11), s. 1017–1024. doi: 10.1111/j.1365-2362.2009.02207.x.
• Fevang, Børre; Eugen-Olsen, Jesper; Yndestad, Arne; Brosstad, Frank Roger; Beiske, Klaus & Aukrust, Pål [Vis alle 7 forfattere av denne artikkelen] (2009). Enhanced levels of urokinase plasminogen activator and its soluble receptor in common variable immunodeficiency. Clinical Immunology. ISSN 1521-6616. 131(3), s. 438–446. doi: 10.1016/j.clim.2009.01.007.
• Smith, Camilla; Halvorsen, Bente ; Otterdal, Kari; Wæhre, Torgun; Yndestad, Arne & Fevang, Børre [Vis alle 13 forfattere av denne artikkelen] (2008). High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins. Cardiovascular Research (CVR). ISSN 0008-6363. 79, s. 195–203. doi: 10.1093/cvr/cvn071.
• Dahl, Christen Peder; Gullestad, Lars; Fevang, Børre; Holm, Are Martin; Landrø, Linn Aina Ysland & Vinge, Leif Erik [Vis alle 15 forfattere av denne artikkelen] (2008). Increased expression of LIGHT/TNFSF 14 and its receptors in experimental and clinical heart failure. European Journal of Heart Failure. ISSN 1388-9842. 10, s. 352–359. doi: 10.1016/j.ejheart.2008.02.010.
• Fevang, Børre; Yndestad, Arne; Sandberg, Wiggo Johan; Holm, Are Martin; Muller, Fredrik & Aukrust, Pål [Vis alle 7 forfattere av denne artikkelen] (2007). Low numbers of regulatory T cells in common variable immunodeficiency: association with chronic inflammation in vivo. Clinical and Experimental Immunology. ISSN 0009-9104. 147. doi: 10.1111/j.1365-2249.2006.03314.x.
• Damås, Jan Kristian; Smith, Camilla; Øie, Erik; Fevang, Børre; Halvorsen, Bente & Waehre, Torgun [Vis alle 19 forfattere av denne artikkelen] (2007). Enhanced expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental atherosclerosis - Possible pathogenic role in plaque destabilization. Arteriosclerosis, Thrombosis and Vascular Biology. ISSN 1079-5642. 27, s. 614–620. doi: 10.1161/01.ATV.0000255581.38523.7c.
• Bjerkeli, Vigdis; Damås, Jan Kristian; Fevang, Børre; Holter, JC; Aukrust, Pål & Frøland, Stig Sophus (2007). Increased expression of fractalkine (CX3CL1) and its receptor, CX3CR1, in Wegener's granulomatosis-possible role in vascular inflammation. Rheumatology. ISSN 1462-0324. 46, s. 1422–1427. doi: 10.1093/rheumatology/kem168.
• Fevang, Børre; Mollnes, Tom Eirik; Holm, Are Martin; Ueland, Thor; Heggelund, Lars & Damås, Jan Kristian [Vis alle 8 forfattere av denne artikkelen] (2005). Common variable immunodeficiency and the complement system; low mannose-binding lectin levels are associated with bronchiectasis. Clinical and Experimental Immunology. ISSN 0009-9104. 142(3), s. 576–584.

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• Jørgensen, Silje Fjellgård; Macpherson, Magnhild Eide; Bjørnetrø, Tonje; Holm, Kristian; Kummen, Martin & Rashidi, Azita [Vis alle 18 forfattere av denne artikkelen] (2024). Retraction to: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency (Scientific Reports, (2019), 9, 1, (167), 10.1038/s41598-018-35367-7). Scientific Reports. ISSN 2045-2322. 14(1). doi: 10.1038/s41598-024-54117-6.
• Nissen-Meyer, Lise Sofie Haug; Macpherson, Magnhild Eide; Skeie, Linda Gail; Hvalryg, Marte; LLOHN, ABID HUSSAIN & Steinsvåg, Tine Torsvik [Vis alle 17 forfattere av denne artikkelen] (2023). Covid-19-pasienter behandlet med rekonvalesensplasma. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 143(11). doi: 10.4045/tidsskr.22.0577. Fulltekst i vitenarkiv
• Nissen-Meyer, Lise Sofie Haug; Hervig, Tor Audun; Fevang, Børre; Norheim, Gunnstein; Kran, Anne-Marte Bakken & Vaage, John T. [Vis alle 7 forfattere av denne artikkelen] (2022). Covid-19-rekonvalesensplasma fra norske blodgivere. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 142(9), s. 768–770. doi: 10.4045/tidsskr.22.0057. Fulltekst i vitenarkiv
• Hurst, John R.; Abbas, S. Hamza; Bintalib, Heba M.; Alfaro, Tiago M; Baumann, Ulrich & Burns, Siobhan O [Vis alle 30 forfattere av denne artikkelen] (2021). Granulomatous-lymphocytic interstitial lung disease: An international research prioritisation. European Respiratory Journal Open Research (ERJ Open Research). ISSN 2312-0541. 7(4). doi: 10.1183/23120541.00467-2021.
• Fevang, Børre; Warnatz, Klaus & Hurst, John R. (2021). Editorial: Interstitial Lung Disease in Primary Immunodeficiencies. Frontiers in Immunology. ISSN 1664-3224. 12. doi: 10.3389/fimmu.2021.699126.
• Jørgensen, Silje Fjellgård; Holm, Kristian; Macpherson, Magnhild Eide; Larsen, Christopher Storm; Kummen, Martin & Fevang, Børre [Vis alle 8 forfattere av denne artikkelen] (2019). Selective IgA deficiency in humans is associated with reduced gut microbial diversity. Journal of Allergy and Clinical Immunology. ISSN 0091-6749. 143(5), s. 1969–1971.e11. doi: 10.1016/j.jaci.2019.01.019.
• Fevang, Børre (2018). Open access - elefanten (eller isbjørnen) i rommet : . Tidsskrift for Den norske legeforening. ISSN 0029-2001. 138(2). doi: 10.4045/tidsskr.18.0019.
• Fevang, Børre; Fagerli, Unn Merete; Sorte, Hanne Sørmo; Aarset, Harald; Hov, Håkon & Langmyr, Marit [Vis alle 11 forfattere av denne artikkelen] (2018). Runaway Train; A Leaky Radiosensitive SCID with Skin Lesions and Multiple Lymphomas. Hindawi (Case Reports in Immunology). doi: 10.1155/2018/2053716.
• Fevang, Per; Havemann, Kirsten; Fevang, Børre & Høstmark, Arne Torbjørn (2018). Malaria and Malnutrition: Kwashiorkor Associated with Low Levels of Parasitaemia .
• Nordheim, Espen; Storrø, Monica Olafsson; Natvik, Ane Kristine; Kro, Grete A Birkeland; Midtvedt, Karsten & Reisæter, Anna Varberg [Vis alle 9 forfattere av denne artikkelen] (2018). Donor-derived strongyloidiasis after organ transplantation in Norway. Transplant Infectious Disease. ISSN 1398-2273. 21(1). doi: 10.1111/tid.13008.
• Fevang, Børre (2017). Open access-elefanten (eller isbjørnen) i rommet :. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 137(23/24), s. 1860–1860. doi: 10.4045/tidsskr.17.1010.
• Jørgensen, Silje Fjellgård; Reims, Henrik Mikael; Aukrust, Pål; Lundin, Knut Erik Aslaksen & Fevang, Børre (2017). CVID and Celiac Disease. American Journal of Gastroenterology. ISSN 0002-9270. 112(2), s. 393–393. doi: 10.1038/ajg.2016.551.
• Jørgensen, Silje Fjellgård; Macpherson, Magnhild E; Bjøro, Kristian; Karlsen, Tom Hemming; Reims, Henrik Mikael & Grzyb, Krzysztof [Vis alle 10 forfattere av denne artikkelen] (2016). Liver transplantation in patients with primary antibody deficiency. Journal of Allergy and Clinical Immunology. ISSN 0091-6749. doi: 10.1016/j.jaci.2016.10.025.
• Taraldsrud, Eli; Floisand, Y; Aukrust, Pål; Rollag, Halvor; Fevang, Børre & Olweus, Johanna (2012). PLASMACYTOID DENDRITIC CELLS HAVE NORMAL FUNCTION IN PATIENTS WITH COMMON VARIABLE IMMUNODEFICIENCY. Journal of Clinical Immunology. ISSN 0271-9142. 32, s. 50–50.
• Dahl, Christen Peder; Gullestad, Lars; Øie, Erik; Fevang, Børre; Holm, Are Martin & Damås, Jan Kristian [Vis alle 8 forfattere av denne artikkelen] (2007). The TNF superfamily cytokine LIGHT: a new inflammatory mediator in heart failure.
• Fevang, Børre & Frøland, Stig Sophus (2010). Profound Perturbation – Immunopathological Mechanisms in Common variable immunodeficency. Unipub forlag.

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