Dag Jacobsen

• Husby, Maren Wennberg; Bjørnsen, Lars Petter Bache-Wiig; Jørgensen, Arve; Lassen, Tone Merete; Jacobsen, Dag & Laugsand, Lars Erik (2024). Feildosering av metotreksat. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 144(6), s. 1–5. doi: 10.4045/tidsskr.23.0657.
• Olsen, Jul Eirik; Vandsemb, Esten Nymoen; Treider, Martin Alavi; Gjertsen, Marit & Jacobsen, Dag (2024). Vedvarende hikke etter perforert kolecystitt. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 144(1), s. 1–6. doi: 10.4045/tidsskr.23.0437.
• Persett, Per Sverre; Bjørnaas, Mari Asphjell; Jacobsen, Dag; Ekeberg, Øivind & Myhren, Hilde (2023). Health-related quality of life in patients discharged from hospital after suicide attempt with violent methods compared to self-poisonings. Nordic Journal of Psychiatry. ISSN 0803-9488. 78(1), s. 37–45. doi: 10.1080/08039488.2023.2257686. Fulltekst i vitenarkiv
• Lao, Yvonne Elisabeth; Heyerdahl, Fridtjof; Jacobsen, Dag & Hovda, Knut Erik (2022). An enzymatic assay with formate oxidase for point-of-care diagnosis of methanol poisoning. Basic & Clinical Pharmacology & Toxicology. ISSN 1742-7835. 131(6), s. 547–554. doi: 10.1111/bcpt.13789. Fulltekst i vitenarkiv
• Hagberg, Guri; Ihle-Hansen, Håkon; Sandset, Else Charlotte; Jacobsen, Dag; Wimmer, Rolf Henning & Ihle-Hansen, Hege (2022). Long Term Cognitive Function After Cardiac Arrest: A Mini-Review. Frontiers in Aging Neuroscience. ISSN 1663-4365. 14, s. 1–8. doi: 10.3389/fnagi.2022.885226.
• Engebretsen, Stine; Bogstrand, Stig Tore; Jacobsen, Dag & Rimstad, Rune (2021). Quality of care, resource use and patient outcome by use of emergency response team compared with standard care for critically ill medical patients in the emergency department: a retrospective single-centre cohort study from Norway. Emergency medicine. ISSN 0013-6654. 11(8), s. 1–9. doi: 10.1136/bmjopen-2020-047264. Fulltekst i vitenarkiv
• Lao, Yvonne Elisabeth; Vartdal, Trond; Frøyshov, Sten; Latimer, Brian; Kværner, Christiane & Mataric, Marija [Vis alle 11 forfattere av denne artikkelen] (2021). Fomepizole dosing during continuous renal replacement therapy–an observational study. Clinical Toxicology. ISSN 1556-3650. doi: 10.1080/15563650.2021.1980581. Fulltekst i vitenarkiv
• Vibeto, Jon Hjellum; Vallersnes, Odd Martin; Dobloug, Andrea; Brekke, Mette; Jacobsen, Dag & Ekeberg, Øivind [Vis alle 7 forfattere av denne artikkelen] (2021). Treating patients with opioid overdose at a primary care emergency outpatient clinic: a cost-minimization analysis. Cost Effectiveness and Resource Allocation. ISSN 1478-7547. 19(1), s. 1–12. doi: 10.1186/s12962-021-00303-6. Fulltekst i vitenarkiv
• Persett, Per Sverre; Ekeberg, Øivind; Jacobsen, Dag; Bjørnaas, Mari Asphjell & Myhren, Hilde (2021). Higher Suicide Intent in Patients Attempting Suicide with Violent Methods Versus Self-Poisoning: A Prospective Study from Norway. Crisis. ISSN 0227-5910. s. 1–8. doi: 10.1027/0227-5910/a000773. Fulltekst i vitenarkiv
• Lao, Yvonne Elisabeth; Goffeng, Anne; Spillum, Barbro Johanne; Jacobsen, Dag; Nakstad, Espen Rostrup & Hovda, Knut Erik (2021). A survey of the antidote preparedness in Norwegian hospitals. European Journal of Hospital Pharmacy (EJHP). ISSN 2047-9956. s. 1–5. doi: 10.1136/ejhpharm-2020-002544. Fulltekst i vitenarkiv
• Engebretsen, Stine; Bogstrand, Stig Tore; Jacobsen, Dag; Vitelli, Valeria & Rimstad, Rune (2020). NEWS2 versus a single-parameter system to identify critically ill medical patients in the emergency department. Resuscitation Plus. ISSN 2666-5204. 3. doi: 10.1016/j.resplu.2020.100020.
• Rimstad, Rune; Jacobsen, Dag & Bogstrand, Stig Tore (2020). NEWS2 versus a single-parameter system to identify critically ill medical patients in the emergency department. Resuscitation Plus. ISSN 2666-5204. doi: 10.1016/j.resplu.2020.100020.
• Engebretsen, Stine; Bogstrand, Stig Tore; Jacobsen, Dag & Rimstad, Rune (2020). Characteristics, management and outcome of critically ill general medical patients in the Emergency Department: An observational study. International Emergency Nursing. ISSN 1755-599X. 54:100939, s. 1–6. doi: 10.1016/j.ienj.2020.100939. Fulltekst i vitenarkiv
• Tollisen, Karen Synnøve Hunting; Lund, Cathrine; Bjerva, Marianne; Dahl, Gry Torsæter; Högvall, Lisa Maria & Sandvik, Leiv [Vis alle 9 forfattere av denne artikkelen] (2020). Clinical impact of chronic substance abuse in a Norwegian ICU-population. Acta Anaesthesiologica Scandinavica. ISSN 0001-5172. s. 1–10. doi: 10.1111/aas.13766. Fulltekst i vitenarkiv
• Lao, Yvonne Elisabeth; Molden, Espen; Kringen, Marianne K.; Annexstad, Ellen Johanne; Sæverud, Håvard Andreassen & Jacobsen, Dag [Vis alle 7 forfattere av denne artikkelen] (2020). Fatal liver failure after therapeutic doses of paracetamol in a patient with Duchenne muscular dystrophy and atypical pharmacogenetic profile of drug-metabolizing enzymes. Basic & Clinical Pharmacology & Toxicology. ISSN 1742-7835. 127(1), s. 47–51. doi: 10.1111/bcpt.13389. Fulltekst i vitenarkiv
• Nakstad, Espen Rostrup; Stær-Jensen, Henrik; Wimmer, Rolf Henning; Henriksen, Julia; Alteheld, Lars Holger & REICHENBACH, ANTJE [Vis alle 17 forfattere av denne artikkelen] (2020). Late awakening, prognostic factors and long-term outcome in out-of-hospital cardiac arrest – results of the prospective Norwegian Cardio-respiratory Arrest Study (NORCAST) . Resuscitation. ISSN 0300-9572. 149, s. 170–179. doi: 10.1016/j.resuscitation.2019.12.031.
• Tollisen, Karen Synnøve Hunting; Bjerva, Marianne; Dahl, Gry Torsæter; Meidell, Nina Knutrud; Sandvik, Leiv & Heyerdahl, Fridtjof [Vis alle 7 forfattere av denne artikkelen] (2019). Acute illness, Co-morbidity and Mortality in a Norwegian Intensive Care Population. . International Journal of Anesthetics and Anesthesiology. ISSN 2377-4630. 6(1). doi: 10.23937/2377-4630/1410084. Fulltekst i vitenarkiv
• Tollisen, Karen Synnøve Hunting; Bjerva, Marianne; Lund, Cathrine; Dahl, Gry Torsæter; Högvall, Lisa Maria & Sandvik, Leiv [Vis alle 8 forfattere av denne artikkelen] (2019). Substance Abuse-Related Admissions in a mixed Norwegian Intensive Care Population. Acta Anaesthesiologica Scandinavica. ISSN 0001-5172. doi: 10.1111/aas.13506. Fulltekst i vitenarkiv
• Skaaland, Helene; Larstorp, Anne Cecilie Kjeldsen; Lindberg, Morten & Jacobsen, Dag (2019). Reference values for osmolal gap in healthy subjects and in medical inpatients. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. doi: 10.1080/00365513.2019.1672086. Fulltekst i vitenarkiv Vis sammendrag

  Methanol and ethylene glycol poisonings are associated with high morbidity and mortality rates if treatment is not initiated early. Since few hospitals measure these toxic alcohols on a 24/7 basis, calculation of the osmolal gap (OG) is an important diagnostic tool. The reference value for the OG lacks consensus. We, therefore, wanted to update the reference value for OG in presumed healthy subjects and study OG values in internal medicine patients. The OG was calculated in 285 patients at the Medical Clinic at Oslo University Hospital, and in 118 healthy blood donors at Vestfold Hospital Trust. OG was calculated by the formula: OG = Measured osmolality − calculated osmolality ((1.86 × s-sodium + s-glucose + s-urea)/0.93) mOsm/kg H2O. In the patients, median OG was 0 mOsm/kg H2O (interquartile range −3 to 3 mOsm/kg H2O, range −16 to103 mOsm/kg H2O). When corrected for one outlier, the central 95% interval for OG was −10 to 20. The healthy blood donors had a median OG of −1 mOsm/kg H2O (interquartile range −3 to1 mOsm/kg H2O, range −13 to 8 mOsm/kg H2O). When corrected for outliers, the reference range was −6 to 5 mOsm/kg H2O. Based on results from a healthy population, we suggest a reference value for the OG of ≤5 mOsm/kg H2O, but also recommend, based on our results from medical inpatients, to keep today's practice for suspecting poisoning with toxic alcohols at an elevated OG of ≥20 mOsm/kg H2O.

• Hassanian-Moghaddam, Hossein; Zamani, Nasim; Roberts, Darren M.; Brent, Jeffrey; McMartin, Kenneth & Aaron, Cynthia [Vis alle 22 forfattere av denne artikkelen] (2019). Consensus statements on the approach to patients in a methanol poisoning outbreak. Clinical Toxicology. ISSN 1556-3650. s. 1–9. doi: 10.1080/15563650.2019.1636992.
• Trydal, Elisabet; Martinsen, Anders B.; Beisland, Frode; Jacobsen, Dag & Holten, Aleksander Rygh (2019). Strukturert mottak av sepsispasienter og oppstart av antibiotika. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 139(9), s. 811–816. doi: 10.4045/tidsskr.18.0216. Vis sammendrag

  BAKGRUNN Akuttmottaket ved Oslo universitetssykehus, Ullevål, innførte i 2017 en egen prosedyre for mottak av pasienter med mistenkt sepsis. Et strukturert sepsismottak skulle utløses hos disse pasientene, spesielt hvis minst to av tre kriterier i skåringsverktøyet Quick Sequential Organ Failure Assessment (qSOFA) var oppfylt. Vi ønsket å undersøke om tiltaket var hensiktsmessig for å oppfylle nasjonale anbefalinger om oppstart av antibiotika innen én time ved behandling av sepsis. MATERIALE OG METODE Voksne pasienter med mistenkt sepsis som ble tatt imot i strukturerte teammottak i perioden 15.5.–15.11.2017 ble inkludert. Det ble gjort en retrospektiv vurdering av om de inkluderte faktisk hadde hatt sepsis eller ikke. RESULTATER Det ble gitt antibiotika mot mistenkt sepsis i 216 strukturerte pasientmottak (172 sepsismottak og 44 medisinske teammottak). 175 (81 %) av pasientene fikk antibiotika innen den første timen i akuttmottaket. Mediantid fra ankomst til antibiotika ble igangsatt var 35 minutter. Bruk av qSOFA-skår alene fanget opp 80 (71 %) av de 112 pasientene som i ettertid ble klassifisert til å ha sepsis. FORTOLKNING Etter innføring av strukturert mottak av pasienter med mistenkt sepsis ble antibiotikabehandling i stor grad gitt innen én time.

• Vangstad, Marie; Bjørnaas, Mari Asphjell & Jacobsen, Dag (2019). Rhabdomyolysis: a 10-year retrospective study of patients treated in a medical department. European journal of emergency medicine. ISSN 0969-9546. 26(3), s. 199–204. doi: 10.1097/MEJ.0000000000000510. Fulltekst i vitenarkiv
• Jørgensen, David; Tazmini, Kiarash & Jacobsen, Dag (2019). Acute Dysnatremias: a dangerous and overlooked clinical problem. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. ISSN 1757-7241. 27(58). doi: 10.1186/s13049-019-0633-3. Fulltekst i vitenarkiv
• Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2019). Mortality and repeated poisoning after self-discharge during treatment for acute poisoning by substances of abuse: a prospective observational cohort study. BMC Emergency Medicine. ISSN 1471-227X. 19. doi: 10.1186/s12873-018-0219-9. Fulltekst i vitenarkiv
• Beitland, Sigrid; Wimmer, Rolf Henning; Lorentsen, Torleif; Jacobsen, Dag; Drægni, Tomas & Brunborg, Cathrine [Vis alle 9 forfattere av denne artikkelen] (2019). Venous thromboembolism in the critically ill: A prospective observational study of occurrence, risk factors and outcome. Acta Anaesthesiologica Scandinavica. ISSN 0001-5172. 63(5), s. 630–638. doi: 10.1111/aas.13316. Fulltekst i vitenarkiv
• Ursin Rein, Pernille; Jacobsen, Dag; Ormaasen, Vidar & Dunlop, Oona Borghild (2018). Pneumococcal sepsis requiring mechanical ventilation: Cohort study in 38 patients with rapid progression to septic shock. Acta Anaesthesiologica Scandinavica. ISSN 0001-5172. 62(10), s. 1428–1435. doi: 10.1111/aas.13236.
• Drangsholt, Elise Rebekka; Vangstad, Marie; Zakharov, Sergey; Hovda, Knut Erik & Jacobsen, Dag (2018). The hypothesis of circulus hypoxicus and its clinical relevance in patients with methanol poisoning - An observational study of 35 patients. Basic & Clinical Pharmacology & Toxicology. ISSN 1742-7835. 123(6), s. 749–755. doi: 10.1111/bcpt.13074.
• Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2018). Factors associated with rapidly repeated acute poisoning by substances of abuse: a prospective observational cohort study. BMC Research Notes. ISSN 1756-0500. 11, s. 1–4. doi: 10.1186/s13104-018-3834-3.
• Persett, Per Sverre; Grimholt, Tine Kristin; Ekeberg, Øivind; Jacobsen, Dag & Myhren, Hilde (2018). Patients admitted to hospital after suicide attempt with violent methods compared to patients with deliberate self-poisoning -a study of background variables, somatic and psychiatric health and suicidal behavior. BMC Psychiatry. ISSN 1471-244X. 18:21, s. 1–10. doi: 10.1186/s12888-018-1602-5.
• Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2018). Mortality, morbidity and follow-up after acute poisoning by substances of abuse: a prospective observational cohort study. Scandinavian Journal of Public Health. ISSN 1403-4948. 47, s. 452–461. doi: 10.1177/1403494818779955. Fulltekst i vitenarkiv
• Grimholt, Tine Kristin; Haavet, Ole Rikard; Jacobsen, Dag; Reitan, Håvard Johnsen & Ekeberg, Øivind (2017). “You Have To Be Healthy And Resourceful To Be Seriously Ill” An Open-Ended Question Study Of Patients Experiences Of Care After Deliberate Self-Poisoning. Suicidology Online. ISSN 2078-5488. 8(20).
• Grimholt, Tine Kristin; Jacobsen, Dag; Haavet, Ole Rikard & Ekeberg, Øivind (2017). Lower suicide intention in patients with personality disorders admitted for deliberate self-poisoning than in patients with other diagnoses. Annals of General Psychiatry. ISSN 1744-859X. 16(1). doi: 10.1186/s12991-017-0145-3.
• Bjerva, Marianne; Berild, Dag & Jacobsen, Dag (2017). En veltrent mann med mekanisk aortaklaffog leggsmerter. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 137(2), s. 113–116. doi: 10.4045/tidsskr.15.1337.
• Beitland, Sigrid; Nakstad, Espen Rostrup; Stær-Jensen, Henrik; Drægni, Tomas; Andersen, Geir Øystein & Jacobsen, Dag [Vis alle 9 forfattere av denne artikkelen] (2016). Impact of acute kidney injury on patient outcome in out-of-hospital cardiac arrest: a prospective observational study. Acta Anaesthesiologica Scandinavica. ISSN 0001-5172. 60(8), s. 1170–1181. doi: 10.1111/aas.12753.
• Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2016). Follow-up after acute poisoning by substances of abuse: a prospective observational cohort study. Scandinavian Journal of Primary Health Care. ISSN 0281-3432. 34, s. 309–316. doi: 10.1080/02813432.2016.1207152. Fulltekst i vitenarkiv
• Vallersnes, Odd Martin; Bjørnaas, Mari Asphjell; Lund, Cathrine; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2016). Follow-up of young patients after acute poisoning by substances of abuse: a comparative cohort study at an emergency outpatient clinic. BMC Research Notes. ISSN 1756-0500. 9. doi: 10.1186/s13104-016-2200-6. Fulltekst i vitenarkiv
• McMartin, Kenneth E.; Jacobsen, Dag & Hovda, Knut Erik (2016). Antidotes for poisoning by alcohols that form toxic metabolites. British Journal of Clinical Pharmacology. ISSN 0306-5251. 81(3), s. 505–515. doi: 10.1111/bcp.12824.
• Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2016). Outpatient treatment of acute poisoning by substances of abuse: a prospective observational cohort study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. ISSN 1757-7241. 24(1). doi: 10.1186/s13049-016-0268-6. Fulltekst i vitenarkiv
• Grimholt, Tine Kristin; Jacobsen, Dag; Haavet, Ole Rikard; Sandvik, Leiv; Jørgensen, Trond & Norheim, Astrid Berge [Vis alle 7 forfattere av denne artikkelen] (2015). Effect of systematic follow-up by general practitioners after deliberate self-poisoning: A randomised controlled trial. PLOS ONE. ISSN 1932-6203. 10:e0143934(12). doi: 10.1371/journal.pone.0143934. Vis sammendrag

  Objective To assess whether systematic follow-up by general practitioners (GPs) of cases of deliberate self-poisoning (DSP) by their patients decreases psychiatric symptoms and suicidal behaviour compared with current practice. Design Randomised clinical trial with two parallel groups. Setting General practices in Oslo and the eastern part of Akershus County. Participants Patients aged 18–75 years admitted to hospital for DSP.We excluded patients diagnosed with psychoses, without a known GP, those not able to complete a questionnaire, and patients admitted to psychiatric in-patient care or other institutions where their GP could not follow them immediately after discharge. Intervention The GPs received a written guideline, contacted the patients and scheduled a consultation within one week after discharge, and then provided regular consultations for six months. We randomised the patients to either intervention (n = 78) or treatment as usual (n = 98). Main Outcome Measures Primary outcome measure was the Beck Scale for Suicide Ideation (SSI). Secondary outcomes were Beck Depression Inventory (BDI) and Beck Hopelessness Scale (BHS), selfreported further self-harm and treatment for DSP in a general hospital or an emergency medical agency (EMA). We assessed patients on entry to the trial and at three and six months. We collected data from interviews, self-report questionnaires, and hospital and EMA medical records. Results There were no significant differences between the groups in SSI, BDI, or BHS mean scores or change from baseline to three or six months. During follow-up, self-reported DSP was 39.5% in the intervention group vs. 15.8% in controls (P = 0.009). Readmissions to general hospitals were similar (13% in both groups (P = 0.963), while DSP episodes treated at EMAs were 17% in the intervention group and 7% in the control group (P = 0.103). Conclusion Structured follow-up by GPs after an episode of DSP had no significant effect on suicide ideation, depression or hopelessness. There was no significant difference in repeated episodes of DSP in hospitals or EMAs. However, the total number of incidents of deliberate self-harm reported by the patients was significantly higher in the intervention group. Trial registration Trial registration ClinicalTrials.gov Identifier: NCT01342809

• Grimholt, Tine Kristin; Jacobsen, Dag; Haavet, Ole Rikard; Sandvik, Leiv; Jørgensen, Trond & Norheim, Astrid Berge [Vis alle 7 forfattere av denne artikkelen] (2015). Structured follow-up by general practitioners after deliberate self-poisoning. A randomized controlled trial. BMC Psychiatry. ISSN 1471-244X. 15(245). doi: 10.1186/s12888-015-0635-2. Vis sammendrag

  Background: General Practitioners (GPs) play an important role in the follow-up of patients after deliberate self-poisoning (DSP). The aim was to examine whether structured follow-up by GPs increased the content of, adherence to, and satisfaction with treatment after discharge from emergency departments. Methods: This was a multicentre, randomised trial with blinded assignment. Five emergency departments and general practices in the catchment area participated. 202 patients discharged from emergency departments after DSP were assigned. The intervention was structured follow-up by the GP over a 6-month period with a minimum of five consultations, accompanied by written guidelines for the GPs with suggestions for motivating patients to follow treatment, assessing personal problems and suicidal ideation, and availability in the case of suicidal crisis. Outcome measures were data retrieved from the Register for the control and payment of reimbursements to health service providers (KUHR) and by questionnaires mailed to patients and GPs. After 3 and 6 months, the frequency and content of GP contact, and adherence to GP consultations and treatment in general were registered. Satisfaction with general treatment received and with the GP was measured by the EUROPEP scale. Results: Patients in the intervention group received significantly more consultations than the control group (mean 6.7 vs. 4.5 (p = 0.004)). The intervention group was significantly more satisfied with the time their GP took to listen to their personal problems (93.1 % vs. 59.4 % (p = 0.002)) and with the fact that the GP included them in medical decisions (87.5 % vs. 54. 8 % (p = 0.009)). The intervention group was significantly more satisfied with the treatment in general than the control group (79 % vs. 51 % (p = 0.026)). Conclusions: Guidelines and structured, enhanced follow-up by the GP after the discharge of the DSP patient increased the number of consultations and satisfaction with aftercare in general practice. Consistently with previous research, there is still a need for interventional studies

• Stær-Jensen, Henrik; Nakstad, Espen Rostrup; Fossum, Eigil; Mangschau, Arild; Eritsland, Jan & Drægni, Tomas [Vis alle 9 forfattere av denne artikkelen] (2015). Post-Resuscitation ECG for Selection of Patients for Immediate Coronary Angiography in Out-of-Hospital Cardiac Arrest. Circulation. Cardiovascular Interventions. ISSN 1941-7640. 8(10). doi: 10.1161/CIRCINTERVENTIONS.115.002784.
• Akopian, Maja; Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2015). Levekår i Oslos bydeler og legevaktbehandlet rusmiddelforgiftning. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 135, s. 1943–1948. doi: 10.4045/tidsskr.15.0370.
• Hovda, Knut Erik; Gadeholt, Gaut; Evtodienko, Vladimir & Jacobsen, Dag (2015). A novel bedside diagnostic test for methanol poisoning using dry chemistry for formate. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 75(7), s. 610–614. doi: 10.3109/00365513.2015.1066847.
• Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2015). Patients presenting with acute poisoning to an outpatient emergency clinic: a one-year observational study in Oslo, Norway. BMC Emergency Medicine. ISSN 1471-227X. 15(18). doi: 10.1186/s12873-015-0045-2. Fulltekst i vitenarkiv
• Stær-Jensen, Henrik; Sunde, Kjetil; Olasveengen, Theresa M.; Jacobsen, Dag; Drægni, Tomas & Nakstad, Espen Rostrup [Vis alle 8 forfattere av denne artikkelen] (2014). Bradycardia during therapeutic hypothermia is associated with good neurologic outcome in comatose survivors of out-of-hospital cardiac arrest. Critical Care Medicine. ISSN 0090-3493. 42(11), s. 2401–2408. doi: 10.1097/CCM.0000000000000515.
• Grimholt, Tine Kristin; Haavet, Ole Rikard; Jacobsen, Dag; Sandvik, Leiv & Ekeberg, Øivind (2014). Perceived competance and attitudes towards patients with suicidal behaviour: a survey of general practitioners, psychiatrists and internists. BMC Health Services Research. ISSN 1472-6963. 14(208). doi: 10.1186/1472-6963-14-208.
• Lund, Cathrine; Bjørnaas, Mari Asphjell; Sandvik, Leiv; Ekeberg, Øivind; Jacobsen, Dag & Hovda, Knut Erik (2013). Five-year mortality after acute poisoning treated in ambulances, an Emergency outpatient clinic and hospitals in Oslo. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. ISSN 1757-7241. 21:65. doi: 10.1186/1757-7241-21-65.
• Paasma, Raido; Hovda, Knut Erik; Hassanian-Moghaddam, Hossein; Brahmi, Nozha; Afshari, Reza & Sandvik, Leiv [Vis alle 7 forfattere av denne artikkelen] (2012). Risk factors related to poor outcome after methanol poisoning and the relation between outcome and antidotes - a multicenter study. Clinical Toxicology. ISSN 1556-3650. 50(9), s. 823–831. doi: 10.3109/15563650.2012.728224.
• Lund, Cathrine; Teige, Brita; Drottning, Per; Stiksrud, Birgitte; Rui, Tor Olav & Lyngra, Marianne [Vis alle 9 forfattere av denne artikkelen] (2012). A one-year observational study of all hospitalized and fatal acute poisonings in Oslo: Epidemiology, intention and follow-up. BMC Public Health. ISSN 1471-2458. 12(1). doi: 10.1186/1471-2458-12-858.
• Lund, Cathrine; Drottning, Per; Stiksrud, Birgitte; Vahabi, Javad; Lyngra, Marianne & Ekeberg, Ivind [Vis alle 8 forfattere av denne artikkelen] (2012). A one-year observational study of all hospitalized acute poisonings in Oslo: complications, treatment and sequelae. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. ISSN 1757-7241. 20(49). doi: 10.1186/1757-7241-20-49.
• Grimholt, Tine Kristin; Bjørnaas, Mari Asphjell; Jacobsen, Dag; Dieserud, Gudrun Klemetsdal & Ekeberg, Øivind (2012). Treatment received, satisfaction with health care services, ansd psychiatric symptoms 3 months after hospitalization for self-poisoning. Annals of General Psychiatry. ISSN 1744-859X. 11. doi: 10.1186/1744-859X-11-10.
• Lund, Cathrine; Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Hovda, Knut Erik (2012). Outpatient treatment of acute poisonings in Oslo : poisoning pattern, factors associated with hospitalization, and mortality. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. ISSN 1757-7241. 20. doi: 10.1186/1757-7241-20-1. Fulltekst i vitenarkiv
• McMartin, Kenneth E.; Sebastian, C. Simon; Dies, David & Jacobsen, Dag (2012). Kinetics and metabolism of fomepizole in healthy humans. Clinical Toxicology. ISSN 1556-3650. 50(5), s. 375–383. doi: 10.3109/15563650.2012.683197.
• Kolvik, Hallgeir; Bjørnaas, Mari Asphjell; Hovda, Knut Erik; Jacobsen, Dag; Ekeberg, Øivind & Heyerdahl, Fridtjof (2011). Levekår og forgiftningsmønster i Oslos bydeler. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 131, s. 1424–1428. doi: 10.4045/tidsskr.10.0531.
• Hovda, Knut Erik; Julsrud, Joar; Øvrebø, Steinar; Brørs, Odd & Jacobsen, Dag (2011). Studies on ethylene glycol poisoning: One patient - 154 admissions. Clinical Toxicology. ISSN 1556-3650. 49(6), s. 478–484. doi: 10.3109/15563650.2011.590140. Vis sammendrag

  Objective. Fomepizole is the antidote of choice in toxic alcohol poisonings. Potential side effects from frequent use of fomepizole were studied in a patient admitted 154 times with ethylene glycol (EG) poisoning. The intra-individual correlation between the serum-ethylene glycol (serum-EG) and the osmolal gap (OG) EG-kinetics, and other laboratory parameters were also studied. Methods. Combined pro- and retrospective collection of material from three different hospitals, and results from autopsy. Results. A 26-year-old female with a dissociative disorder was admitted with EG poisoning a total of 154 times. Her admission data revealed a median pH of 7.31 (range 6.87–7.49), pCO2: 4.2 kPa (1.2–6.7) (32 mmHg [9–50]), HCO–3: 15 mmol/L (4–26) (15 mEq/L [4–26]), base deficit (BD): 10 mmol/L (− 4 to 27) (10 mEq/L [–4 to 27]), serum-creatinine 65 μmol/L (40–133) (0.74 mg/dL [0.45–1.51]), OG 81 mOsm/kgH2O (25–132), and serum-EG 44 mmol/L (4–112) (250 mg/dL [25–700]). She was treated with fomepizole 99 times, ethanol 60 times (with a combination of both six times), and dialysis 73 times. The correlation between serum-EG and OG was good (r2 = 0.76). She was finally found dead outside hospital with an EG blood concentration of 81 mmol/L (506 mg/dL). An autopsy revealed calcium oxalate crystals in the kidneys, slight liver steatosis, and slight edema of the lungs. Discussion. The frequent use of fomepizole in this young patient was not associated with any detectable side effects; neither on clinical examination and lab screening, nor on the later autopsy. Regarding the sequelae from the repetitive EG-poisoning episodes, her kidney function seemed to normalize after each overdose. She was treated with buffer and antidote without hemodialysis 81 times without complications, supporting the safety of this approach in selected cases.

• TØMTE, ØYSTEIN; Andersen, Geir Øystein; Jacobsen, Dag; Drægni, Tomas; Auestad, Bjørn & Sunde, Kjetil (2011). Strong and weak aspects of an established post-resuscitation treatment protocol-A five-year observational study. Resuscitation. ISSN 0300-9572. 82(9), s. 1186–1193. doi: 10.1016/j.resuscitation.2011.05.003.
• TØMTE, ØYSTEIN; Drægni, Tomas; Mangschau, Arild; Jacobsen, Dag; Auestad, Bjørn & Sunde, Kjetil (2011). A comparison of intravascular and surface cooling techniques in comatose cardiac arrest survivors. Critical Care Medicine. ISSN 0090-3493. 39(3), s. 443–449. doi: 10.1097/CCM.0b013e318206b80f.
• TØMTE, ØYSTEIN; Drægni, Tomas; Mangschau, Arild; Jacobsen, Dag; Auestad, Bjørn H. & Sunde, Kjetil (2010). A comparison of intravascular and surface cooling techniques in comatose cardiac arrest survivors. Critical Care Medicine. ISSN 0090-3493. doi: 10.1097/CCM.0b013e318206b80f.
• Bjørnaas, Mari Asphjell; Teige, Brita; Hovda, Knut Erik; Ekeberg, Øivind; Heyerdahl, Fridtjof & Jacobsen, Dag (2010). Fatal poisonings in Oslo: A one-year observational study. BMC Emergency Medicine. ISSN 1471-227X. 10(6), s. 10–13. doi: 10.1186/1471-227X-10-13.
• Bjørnaas, Mari Asphjell; Hovda, Knut Erik; Heyerdahl, Fridtjof; Skog, Karina; Drottning, Per & Opdahl, Anders [Vis alle 8 forfattere av denne artikkelen] (2010). Suicidal intention, psychosocial factors and referral to further treatment: A one-year cross-sectional study of self-poisoning. BMC Psychiatry. ISSN 1471-244X. 10. doi: 10.1186/1471-244X-10-58.
• Heyerdahl, Fridtjof; Bjørnaas, Mari Asphjell; Dahl, Rune; Hovda, Knut Erik; Nore, AK & Ekeberg, Øivind [Vis alle 7 forfattere av denne artikkelen] (2009). Repetition of acute poisoning in Oslo: 1-year prospective study. British Journal of Psychiatry. ISSN 0007-1250. 194(1), s. 73–79. doi: 10.1192/bjp.bp.107.048322.

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• Mjølstad, Ole Christian; Radtke, Maria Anita; Brodtkorb, Eylert; Edvardsen, Frode; Wenche Rødseth, Brede & Aamo, Trond Oskar [Vis alle 9 forfattere av denne artikkelen] (2023). Recurrent malignant ventricular arrhythmias and paresthesia—a mystery revealed as aconitine poisoning: a case report. Journal of Medical Case Reports. ISSN 1752-1947. doi: 10.1186/s13256-023-04304-2. Fulltekst i vitenarkiv
• Jacobsen, Dag (2023). En gass til lyst og besvær. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 143(1). doi: 10.4045/tidsskr.22.0735.
• Hovda, Knut Erik; Lao, Yvonne Elisabeth; Gadeholt, Gaut & Jacobsen, Dag (2021). Formate test for bedside diagnosis of methanol poisoning. Basic & Clinical Pharmacology & Toxicology. ISSN 1742-7835. 129(1), s. 86–88. doi: 10.1111/bcpt.13597.
• Kvåle, Gunnar; Gilbert, Mads; Klein, Jørn; Svanæs, Dag; Jacobsen, Dag & Eldjarn, Knut [Vis alle 7 forfattere av denne artikkelen] (2021). «Slå ned» og hold nede til befolkningen er vaksinert! VG : Verdens gang. ISSN 0805-5203. Vis sammendrag

  https://www.vg.no/nyheter/meninger/i/qAvGWg/slaa-ned-og-hold-nede-til-befolkningen-er-vaksinert?

• Jacobsen, Dag; Gilbert, Mads; Kvåle, Gunnar & Klein, Jørn (2021). Ny nedstenging må til om mutert virus skal slås ned! VG : Verdens gang. ISSN 0805-5203. Vis sammendrag

  https://www.vg.no/nyheter/meninger/i/M3Ej8o/ny-nedstenging-maa-til-om-mutert-virus-skal-slaas-ned?

• Jacobsen, Dag; Gilbert, Mads & Kvåle, Gunnar (2021). Vi trenger nasjonale tiltak nå! VG : Verdens gang. ISSN 0805-5203. Vis sammendrag

  https://www.vg.no/nyheter/meninger/i/2dqE1a/vi-trenger-nasjonale-tiltak-naa

• Flaaten, Hans; Gilbert, Mads; Kvåle, Gunnar; Jacobsen, Dag & Svanæs, Dag (2020). Sterkere tiltak - Ikke letteler. VG : Verdens gang. ISSN 0805-5203. Vis sammendrag

  https://www.vg.no/nyheter/meninger/i/4qeRX9/sterkere-tiltak-ikke-lettelser

• Svanæs, Dag; Andersen, Bjørg Marit; Gilbert, Mads; Kvåle, Gunnar; Klein, Joern & Jacobsen, Dag [Vis alle 12 forfattere av denne artikkelen] (2020). Da COVID-19 kom til Norge. Den uoffisielle historien. Vis sammendrag

  "Coronakritikk.no" is a collection of published newspaper articles and opinion pieces (in Norwegian) that question various aspects of the Norwegian authorities' handling of the COVID-19 crisis. The collection is organized as an archive.

• Klein, Jörn; Hasle, Gunnar; Eldjarn, Knut; Jacobsen, Dag; Svanæs, Dag & Nyborg, Gunhild Alvik [Vis alle 7 forfattere av denne artikkelen] (2020). Flokkimmunitet uten smittevern og vaksine er en farlig korona-strategi. Dagens medisin. ISSN 1501-4290.
• Svanæs, Dag; Kvåle, Gunnar; Andersen, Bjørg Marit; Eldjarn, Knut; Klein, Jørn & Hasle, Gunnar [Vis alle 11 forfattere av denne artikkelen] (2020). Ti myter om pandemien. Dagbladet. ISSN 0805-3766. s. 38–39.
• Kvåle, Gunnar; Flaatten, Hans; Gilbert, Mads & Jacobsen, Dag (2020). Korona kan stoppes med enda strengere tiltak. Bergens Tidende. ISSN 0804-8983.
• Vibeto, Jon Hjellum; Vallersnes, Odd Martin; Dobloug, Andrea; Brekke, Mette; Jacobsen, Dag & Ekeberg, Øivind [Vis alle 7 forfattere av denne artikkelen] (2020). Treating patients with opioid overdose at a primary care emergency outpatient clinic: a cost-minimization analysis.
• Vangstad, Marie; Bjørnaas, Mari Asphjell & Jacobsen, Dag (2018). Treningsindusert rabdomyolyse. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 138(1). doi: 10.4045/tidsskr.17.1079.
• Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2018). Morbidity and follow-up after acute poisoning by substances of abuse.
• Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2017). Factors associated with rapidly repeating acute poisoning by substances of abuse.
• Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2017). Patients self-discharging during treatment for acute poisoning by substances of abuse.
• Hovda, Knut Erik; Gadeholt, Gaut & Jacobsen, Dag (2016). Ethanol strips for monitoring of ethanol concentrations during treatment of toxic alkohol: preliminary results.
• Höjer, Jonas; Jacobsen, Dag; Neuvonen, Pertti J. & Rosenberg, Per H. (2016). Lipid rescue – efficacy and safety still unproven. Basic & Clinical Pharmacology & Toxicology. ISSN 1742-7835. 119(4), s. 345–348. doi: 10.1111/bcpt.12607.
• Vallersnes, Odd Martin; Bjørnaas, Mari Asphjell; Lund, Cathrine; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2016). Follow-up of young patients after acute poisoning by substances of abuse: a comparative cohort study at an emergency outpatient clinic.
• Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2016). Outpatient treatment of acute poisoning by substances of abuse: a 1-year prospective observational study.
• Rimul, Gunnar; Kormeset, Per Olav; Jacobsen, Dag; Hortemo, Sigurd & Ulshagen, Karen Marie (2015). Fortsatt salg av paracetamol i butikk. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 135(4), s. 316–317. doi: 10.4045/tidsskr.14.1563.
• Stær-Jensen, Henrik; Nakstad, Espen Rostrup; Fossum, E; Mangschau, Arild; Eritsland, Jan & Jacobsen, Dag [Vis alle 8 forfattere av denne artikkelen] (2014). Emergency coronary angiography and revascularization in patients with out of hospital cardiac arrest - relation to post - ROSC ECG - a prospective observational study.
• Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2014). Akutte forgiftninger ved Legevakten i Oslo: en ett-års observasjonsstudie.
• Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Brekke, Mette (2014). Patients presenting with acute poisoning to an outpatient emergency clinic in Oslo: a one year prospective observational study.
• Heyerdahl, Fridtjof; Bjørnaas, Mari Asphjell; Lund, Cathrine; Jacobsen, Dag & Ekeberg, Øivind (2013). Long-term follow-up of three cohorts of self-poisoning. Clinical Toxicology. ISSN 1556-3650. 51(4), s. 254–254.
• Lund, Caroline; Hovda, Knut Erik; Gudmundsdottir, Helga; Andersson, Kirsti Svendsen; NYVOLD, CECILIE & Froyshov, Sten [Vis alle 8 forfattere av denne artikkelen] (2013). Severe metformin-induced lactic acidosis: Case series of 10 patients. Clinical Toxicology. ISSN 1556-3650. 51(4), s. 365–365.
• Paasma, Raido; Hovda, Knut Erik; Hassanian-Moghaddan, H; Brahmi, Nozha; Afshari, Reza & Sandvik, Leiv [Vis alle 7 forfattere av denne artikkelen] (2013). Response to the letter "Risk assessment of methanol poisoning in outbreaks not applicable to isolated cases". Clinical Toxicology. ISSN 1556-3650. 51(2), s. 120–120. doi: 10.3109/15563650.2013.764430.
• Heyerdahl, Fridtjof; Opdahl, Helge & Jacobsen, Dag (2012). The Role of the Norwegian Competence Centre for NBC Medicine during the Non-CBRN Terrorist Attacks in Norway on 22 July 2011. Clinical Toxicology. ISSN 1556-3650. 50(4), s. 276–276.
• Heyerdahl, Fridtjof; Haavind, Anniken & Jacobsen, Dag (2012). A Fatal Case of Suicidal Injection and Ingestion of Self-Extracted Ricin. Clinical Toxicology. ISSN 1556-3650. 50(4), s. 290–290.
• Hovda, Knut Erik; Refsum, Helge & Jacobsen, Dag (2012). A Case of Extraordinary High Serum-Venlafaxine and Prolonged Elimination without Genetic Predisposal. Clinical Toxicology. ISSN 1556-3650. 50(4), s. 324–325.
• Paasma, Raido; Hovda, Knut Erik; Hassanian-Moghaddan, H; Brahmi, Nozha; Afshari, Reza & Jacobsen, Dag (2012). Risk Assessment Score for Methanol Poisoning. Clinical Toxicology. ISSN 1556-3650. 50(4), s. 350–351.
• Lund, Cathrine; Vallersnes, Odd Martin; Jacobsen, Dag; Ekeberg, Øivind & Hovda, Knut Erik (2011). Acute poisonings treated at the outpatient accident and emergency clinic (EMA) in Oslo, 2008.
• BERG, THEA CHRISTINE SCHOU; Skjerdal, Jatrud W.; Muan, Berit & Jacobsen, Dag (2011). A Case Report Concerning Monochloroacetic Acid. Clinical Toxicology. ISSN 1556-3650. 49(3), s. 255–255.
• Spillum, Bjørg; Tosterud, M.; Nilssen, Dag Egil; Paulsen, Berit Smestad & Jacobsen, Dag (2011). Coma After Intake of an Unknown Plant Root - Unintentional Anticholinergic Intoxication. Clinical Toxicology. ISSN 1556-3650. 49(3), s. 231–231.
• Bjørnaas, Mari Asphjell; Jacobsen, Eva-Marie & Jacobsen, Dag (2010). Nonfatal self-poisoning with LMW heparin and the use of antidote. Thrombosis Research. ISSN 0049-3848. 126(5), s. E403–E405. doi: 10.1016/j.thromres.2010.08.026.
• Bjørnaas, Mari Asphjell; Jacobsen, Eva-Marie & Jacobsen, Dag (2010). Non-fatal self-poisoning by LMW Heparin and the use of antidote. Thrombosis Research. ISSN 0049-3848. 126(5), s. e403–e405. doi: 10.1016/j.thromres.2010.08.026.
• Lund, Cathrine; Christensen, Hege Staaland; Frøyshov, Sten & Jacobsen, Dag (2010). Toxicokinetics of Diltiazem and Three Metabolites During Acute Life-Threatening Poisoning. Clinical Toxicology. ISSN 1556-3650. 48(3), s. 281–281.
• Bjørnaas, Mari Asphjell; Jacobsen, Eva-Marie & Jacobsen, Dag (2010). Non-Fatal Self-Poisoning by Low Molecular Weight Heparin and the Use of Antidote. Clinical Toxicology. ISSN 1556-3650. 48(3), s. 300–300.
• Bjornaas, MA; Bjørnaas, Mari Asphjell; Teige, Brita; Hovda, KE; Heyerdahl, F & Ekeberg, O [Vis alle 7 forfattere av denne artikkelen] (2009). Deaths by self-poisoning in Oslo and the surrounding area during one year. Clinical Toxicology. ISSN 1556-3650. 47(5), s. 504–505.

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