- Førsteamanuensis
- Overlege hjertekirurgi (OUS)
Bakgrunn
- Universitetet i Bergen (cand. med. 1999)
- Universitetet i Oslo (Ph.D. 2011)
Interesser
- hjertekirurgi
- klaffekirurgi
- atrieflimmer
- blodfortynnende medisin
- blødning
- hjerneslag
- registre
Publikasjoner
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Mortensen, Michael; Nilsen, Roy Miodini; Kvalheim, Venny Lise; BJØRNSTAD, JOHANNES; Svendsen, Øyvind Sverre & Haaverstad, Rune
[Vis alle 7 forfattere av denne artikkelen]
(2023).
The influence of socio-demographic and clinical factors on sick leave and return to work after open-heart surgery: a nationwide registry-based cohort study.
European Heart Journal - Quality of Care and Clinical Outcomes.
ISSN 2058-5225.
s. 1–14.
doi:
10.1093/ehjqcco/qcad064.
Fulltekst i vitenarkiv
Vis sammendrag
Aims
To estimate sick leave (SL) duration after first-time elective open-heart surgery and identify factors contributing to increased SL.
Methods and results
A retrospective nationwide cohort study combined data from the Norwegian Register for Cardiac Surgery and SL data from the Norwegian Labour and Welfare Administrations. All able-bodied adults who underwent first-time elective open-heart surgery in Norway between 2012 and 2021 were followed until 1 year after surgery. The impact of socio-demographic and clinical factors on SL after surgery was analysed using logistic regression and odds ratios. Of 5456 patients, 1643 (30.1%), 1798 (33.0%), 971 (17.8%), 1035 (18.9%), and 9 (0.2%) had SL of <3, 3–6, 6–9, and 9–12 months, and 1 year, respectively. SL >6 months was associated with female gender, primary education only, and average annual income. Post-operative stroke, post-operative renal failure, New York Heart Association Functional Classification system (NYHA) score >3, earlier myocardial infarction, and diabetes mellitus increased the odds of SL >6 months.
Conclusion
This study demonstrates that socio-demographic and clinical factors impact SL after first-time elective open-heart surgery. Patients who experience a stroke or develop renal failure after surgery have the highest odds of SL >6 months. Females and patients with low education levels, earlier myocardial infarction, or NYHA scores III–IV have a two-fold chance of SL >6 months. The findings allow for future investigations of pre- and post-surgery interventions that can most effectively reduce SL and aid return to work.
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Helgeland, Erik; Andresen, Kristoffer; Dumont, Karl-Andreas & BJØRNSTAD, JOHANNES
(2020).
Leaflet fracture and embolization from an On-X mechanical mitral valve.
JTCVS Techniques.
ISSN 2666-2507.
s. 140–143.
doi:
10.1016/j.xjtc.2020.06.021.
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Nuru, Abdul; Hagesveen Weltzien, Joachim; Sandvik, Leiv; Tønnessen, Theis & BJØRNSTAD, JOHANNES
(2019).
Short- and long-term survival after isolated coronary artery bypass grafting, the impact of gender and age.
Scandinavian Cardiovascular Journal.
ISSN 1401-7431.
s. 1–6.
doi:
10.1080/14017431.2019.1646430.
Fulltekst i vitenarkiv
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Majak, Piotr; Lunde, Ida Gjervold; Hasic, Almira; Husebye, Trygve Guttorm; Christensen, Geir Arve & Tønnessen, Theis
[Vis alle 7 forfattere av denne artikkelen]
(2015).
Reduced visfatin levels in aortic stenosis increase after aortic valve replacement and may contribute to reverse left ventricular remodelling.
Journal of Cardiovascular Surgery.
ISSN 0021-9509.
56(3),
s. 483–492.
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Engebretsen, Kristin V Thunheim; Lunde, Ida Gjervold; Strand, Mari Elen; Sjaastad, Ivar; Marstein, Henriette & Skrbic, Biljana
[Vis alle 12 forfattere av denne artikkelen]
(2013).
Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli.
The FEBS Journal.
ISSN 1742-464X.
280(10),
s. 2382–2398.
doi:
10.1111/febs.12235.
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Engebretsen, Kristin V Thunheim; Wæhre, Anne; BJØRNSTAD, JOHANNES; Skrbic, Biljana; Sjaastad, Ivar & Behmen, Dina
[Vis alle 11 forfattere av denne artikkelen]
(2013).
Decorin, lumican, and their GAG chain-synthesizing enzymes are regulated in myocardial remodeling and reverse remodeling in the mouse.
Journal of applied physiology.
ISSN 8750-7587.
114(8),
s. 988–997.
doi:
10.1152/japplphysiol.00793.2012.
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Majak, Piotr; BJØRNSTAD, JOHANNES; Braathen, Bjørn; Lunde, Ida Gjervold; Husebye, Trygve Guttorm & Christensen, Geir Arve
[Vis alle 7 forfattere av denne artikkelen]
(2012).
Endothelin-1 in the Human Myocardium and Circulating Plasma: Evaluation before, during and after Correction of Aortic Stenosis with Aortic Valve Replacement.
Cardiology.
ISSN 0008-6312.
123(1),
s. 1–10.
doi:
10.1159/000339756.
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Majak, Piotr; Braathen, Bjørn; BJØRNSTAD, JOHANNES & Tønnessen, Theis
(2012).
GDF-15 is increased during early reperfusion following aortic valve replacement.
Scandinavian Cardiovascular Journal.
ISSN 1401-7431.
46(2),
s. 99–106.
doi:
10.3109/14017431.2011.649489.
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Bjørnstad, Johannes L.; Skrbic, Biljana; Sjaastad, Ivar; Bjørnstad, Sigrid; Christensen, Geir Arve & Tønnessen, Theis
(2012).
A mouse model of reverse cardiac remodelling following banding-debanding of the ascending aorta.
Acta Physiologica.
ISSN 1748-1708.
205(1),
s. 92–102.
doi:
10.1111/j.1748-1716.2011.02369.x.
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Majak, Piotr; Bjørnstad, Johannes; Vengen, Øystein; Neverdal, Nils Olav; Husebye, Trygve & Woldbæk, Per R
[Vis alle 10 forfattere av denne artikkelen]
(2010).
Plasma IL-18 and IL-18BP are altered differently in reverse remodeling following aortic valve replacement.
Scandinavian Cardiovascular Journal.
ISSN 1401-7431.
44(2),
s. 113–118.
doi:
10.3109/14017430903426902.
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Bjørnstad, Johannes; Pillgram-Larsen, Johan & Tønnessen, Theis
(2009).
Coronary artery dissection and acute myocardial infarction following blunt chest trauma.
World Journal of Emergency Surgery.
ISSN 1749-7922.
14(4).
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Bjørnstad, Johannes; Neverdal, Nils Olav; Vengen, Øystein; Knudsen, Cathrine Wold; Husebye, Trygve & Pepper, John
[Vis alle 9 forfattere av denne artikkelen]
(2008).
Alterations in circulating activin A, GDF-15, TGF-beta 3 and MMP-2,-3, and-9 during one year of left ventricular reverse remodelling in patients operated for severe aortic stenosis.
European Journal of Heart Failure.
ISSN 1388-9842.
10(12),
s. 1201–1207.
doi:
10.1016/j.ejheart.2008.09.010.
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Røed-Undlien, Henriette; Schultz, Nina Haagenrud; Lunnan, Asbjørn; Husebråten, Inger Marie; Wollmann, Birgit Malene Tovik & Molden, Espen
[Vis alle 7 forfattere av denne artikkelen]
(2024).
Corrigendum to < IN-VITRO APIXABAN REMOVAL BY CYTOSORB® WHOLE BLOOD ADSORBER. AN EXPERIMENTAL STUDY.> <[Journal of Cardiothoracic and Vascular Anesthesia 36/6 (2024) 1636 – 1644]> (Journal of Cardiothoracic and Vascular Anesthesia (2022) 36(6) (1636–1644), (S1053077022000726), (10.1053/j.jvca.2022.01.038)).
Journal of Cardiothoracic and Vascular Anesthesia.
ISSN 1053-0770.
doi:
10.1053/j.jvca.2024.03.039.
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Mortensen, Michael; Nilsen, Roy Miodini; Kvalheim, Venny Lise; BJØRNSTAD, JOHANNES; Svendsen, Øyvind Sverre & Haaverstad, Rune
[Vis alle 7 forfattere av denne artikkelen]
(2023).
The impact of clinical and sociodemographic factors on sick leave after cardiac surgery
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Mortensen, Michael; Nilsen, Roy Miodini; Kvalheim, Venny Lise; BJØRNSTAD, JOHANNES; Svendsen, Øyvind Sverre & Haaverstad, Rune
[Vis alle 7 forfattere av denne artikkelen]
(2022).
Kliniske og sosiodemografiske faktorer som fører til lengre sykemelding etter hjertekirurgi.
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Bjørnstad, Johannes Lagethon; Helgeland, Erik; Geiran, Odd & Fiane, Arnt Eltvedt
(2021).
Hjertekirurgi og hjerneskade.
Hjerteforum.
ISSN 0802-1465.
34(2),
s. 104–105.
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Skrbic, Biljana; Engebretsen, Kristin V Thunheim; Strand, Mari Elen; Marstein, Henriette; Sjaastad, Ivar & Lunde, Ida Gjervold
[Vis alle 10 forfattere av denne artikkelen]
(2013).
Lack of collagen type 8 in pressure overload causes left ventricular dilatation and overt heart failure in mice, suggesting a role in transition to heart failure in patients with aortic stenosis.
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Skrbic, Biljana; Engebretsen, Kristin V Thunheim; Strand, Mari Elen; Marstein, Henriette; Sjaastad, Ivar & Lunde, Ida Gjervold
[Vis alle 10 forfattere av denne artikkelen]
(2013).
Lack of collagen type 8 in pressure overload causes left ventricular dilatation and overt heart failure in mice, suggesting a role in transition to heart failure in patients with aortic stenosis.
Circulation.
ISSN 0009-7322.
128.
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Engebretsen, Kristin V Thunheim; Skårdal, Kristine; Bjørnstad, S; Marstein, Henriette; Skrbic, Biljana & Sjaastad, Ivar
[Vis alle 9 forfattere av denne artikkelen]
(2013).
Inhibiting phosphorylation of SMAD2/3 by the small molecule SM16 in left ventricular pressure overload reduces fibrosis and signs of heart failure, possibly due to better diastolic function.
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Skrbic, Biljana; Engebretsen, Kristin V Thunheim; Marstein, Henriette; Sjaastad, Ivar; Christensen, Geir Arve & BJØRNSTAD, JOHANNES
[Vis alle 7 forfattere av denne artikkelen]
(2012).
Reduction in collagen type 8 might be involved in transition from compensated hypertrophy to left ventricular dilatation and overt heart failure in pressure overload.
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Engebretsen, Kristin V Thunheim; Lunde, Ida Gjervold; Wæhre, Anne; Strand, Mari Elen; Sjaastad, Ivar & Marstein, Henriette
[Vis alle 11 forfattere av denne artikkelen]
(2012).
The collagen-organizing proteoglycan lumican is increased in experimental and clinical heart failure and its production by cardiac fibroblasts is induced by pro-inflammatory and mechanical stimuli.
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Engebretsen, Kristin V Thunheim; BJØRNSTAD, JOHANNES; Skrbic, Biljana; Marstein, Henriette; Sjaastad, Ivar & Wæhre, Anne
[Vis alle 8 forfattere av denne artikkelen]
(2011).
Endret nivå av small leucine rich proteoglycans i en musemodell som etterligner pasienter operert for aortastenose.
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Skrbic, Biljana; BJØRNSTAD, JOHANNES; Marstein, Henriette; Sjaastad, Ivar; Nygård, Ståle & Christensen, Geir Arve
[Vis alle 7 forfattere av denne artikkelen]
(2011).
Reduksjon i kollagen VIII kan være involvert i venstre ventrikkel dilatasjon og overgang fra kompensert hypertrofi til dekompensert hjertesvikt ved trykkoverbelastning.
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Skrbic, Biljana; BJØRNSTAD, JOHANNES; Marstein, Henriette; Sjaastad, Ivar; Nygård, Ståle & Christensen, Geir Arve
[Vis alle 7 forfattere av denne artikkelen]
(2011).
Reduction in collagen type 8 might be involved in transition from compensated hypertrophy to left ventricular dilatation and overt heart failure in pressure overload.
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Engebretsen, Kristin V Thunheim; BJØRNSTAD, JOHANNES; Skrbic, Biljana; Marstein, Henriette; Sjaastad, Ivar & Wæhre, Anne
[Vis alle 8 forfattere av denne artikkelen]
(2011).
Correction of left ventricular pressure overload leads to altered myocardial expression of small leucine rich proteoglycans.
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Nygård, Ståle; Reitan, Trond; Clancy, Trevor; Nygaard, Vegard; BJØRNSTAD, JOHANNES & Tønnessen, Theis
[Vis alle 8 forfattere av denne artikkelen]
(2011).
Identifying pathogenic signaling and regulatory networks by integrating microarray data with prior knowledge.
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Nygård, Ståle; Reitan, Trond; Clancy, Trevor; Nygaard, Vegard; BJØRNSTAD, JOHANNES & Tønnessen, Theis
[Vis alle 8 forfattere av denne artikkelen]
(2011).
Identifying pathogenic signaling and regulatory networks by integrating microarray data with prior knowledge.
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Nygård, Ståle; Nygaard, Vigdis; Clancy, Trevor; BJØRNSTAD, JOHANNES; Skrbic, Biljana & Sjaastad, Ivar
[Vis alle 9 forfattere av denne artikkelen]
(2010).
Integrating microarray gene expression data with prior knowledge about molecular interactions for identification of important heart failure pathways.
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Skrbic, Biljana; BJØRNSTAD, JOHANNES; Marstein, Henriette; Sjaastad, Ivar; Nygård, Ståle & Christensen, Geir Arve
[Vis alle 7 forfattere av denne artikkelen]
(2010).
Reduction in collagen VIII might be involved in transition from compensated hypertrophy to overt heart failure in pressure overload.
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Nygård, Ståle; Nygaard, Vigdis; Clancy, Trevor; BJØRNSTAD, JOHANNES; Skrbic, Biljana & Tønnessen, Theis
[Vis alle 8 forfattere av denne artikkelen]
(2010).
Integrating microarray gene expression data with prior knowledge about molecular interactions for identification of important heart failure pathways.
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BJØRNSTAD, JOHANNES; Sjaastad, Ivar; Nygård, Ståle; Finsen, Alexandra; Hasic, Almira & Christensen, Geir Arve
(2010).
The pro-inflammatory adipocytokine visfatin might play a role regulating cardiac metabolism in human and experimental aortic stenosis.
European Journal of Heart Failure. Supplements.
ISSN 1567-4215.
9,
s. S220–S220.
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BJØRNSTAD, JOHANNES; Skrbic, Biljana; Marstein, Henriette; Sjaastad, Ivar; Louch, William Edward & Christensen, Geir Arve
[Vis alle 7 forfattere av denne artikkelen]
(2010).
Inhibiting phosphorylation of SMAD2 preserves cardiac function during pressure overload by attenuating left ventricular SERCA2 loss.
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BJØRNSTAD, JOHANNES; Skrbic, Biljana; Marstein, Henriette; Sjaastad, Ivar; Christensen, Geir Arve & Tønnessen, Theis
(2009).
Inhibiting phosphorylation of SMAD2 preserves cardiac function during pressure overload.
Circulation.
ISSN 0009-7322.
120,
s. S857–S857.
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BJØRNSTAD, JOHANNES; Sjaastad, Ivar; Nygård, Ståle; Finsen, Alexandra; Hasic, Almira & Attramadal, Håvard
[Vis alle 9 forfattere av denne artikkelen]
(2009).
Reverse remodeling of the left ventricle during the early phase after relief of pressure overload in a mouse model.
Hjerteforum.
ISSN 0802-1465.
22,
s. 110–110.
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BJØRNSTAD, JOHANNES; Skrbic, Biljana; Marstein, Henriette; Sjaastad, Ivar; Christensen, Geir Arve & Tønnessen, Theis
(2009).
Inhibiting phosphorylation of SMAD2 preserves cardiac function during pressure overload.
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BJØRNSTAD, JOHANNES; Sjaastad, Ivar; Finsen, Alexandra; Nygård, Ståle; Hasic, Almira & Christensen, Geir Arve
(2008).
Reversible pressure overload alters expression of actin binding and extracellular matrix genes.
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Publisert
16. sep. 2019 10:11
- Sist endret
28. sep. 2022 14:16