We will begin with an introductory talk on the techniques and capabilities by the SciLife Lab's CryoEM facility team, followed by a presentation by equipment manufacturers Thermo and Jeol. The scientific part of the program will begin after lunch. On Thursday, the program will continue at Radiumhospitalet with hands-on demonstrations.
Venue for Wednesday, 18th October 2023:
Room Forum, ground floor
Forskningsparken (Oslo science park)
Gaustadalleén 21, Oslo
Venue for Thursday, 19th October 2023:
NOTE: Venue change:
10:00-12:00: Room Kino, Forskningsparken (Oslo Science Park)
Link to Teams stream: Click here to join the meeting
14:00-16:00: Research-building (K-building, Oslo science park, seminar room 1)
The Norwegian Radium Hospital, Montebello, 0379 Oslo, Norwa
Program
Wednesday, 18th October 2023 (Forskningsparken, room Forum)
09:30 CryoEM and CryoET – emerging technique for understanding structure and function of biomolecules
Gunnar von Heijne & Marta Carroni (SciLifeLab CryoEM facility)
10:00 SciLifeLab CryoEM facility – establishment, organization, capabilities
Gunnar von Heijne & Marta Carroni (SciLifeLab CryoEM facility)
10:30 Advances and Frontiers in cryoEM
Rebecca Thompson (ThermoFisher Scientific)
11:00 Introduction to the JEOL CRYO ARM series – technology, applications and outlook
Emanuel Katzmann (Jeol)
11:30 Understanding biomolecular behaviour with mass photometry
João Pedro Maurício Rosa (Refeyn)
11:45 Lunch
13:00 Opening words
CHROMATIN: How we use cryoEM to learn about centromeric chromatin
Nikolina Sekulić (University of Oslo, Norway)
13:10 PX Oslo - Structural biology core facility
Mateu Montserrat Canals (University of Oslo, Norway)
13:20 BioCat – National graduate school in biocatalysis
Flore Kersten (University of Oslo, Norway)
13:30 PROTEIN FOLDING: Cotranslational protein folding studied (in part...) by Cryo-EM
Gunnar von Heijne (Stockholm University, Sweden)
Host: Ute Krengel
14:05 NEUROBIOLOGY: In situ cryo-electron tomography of β-amyloid and tau in post-mortem Alzheimer’s disease brain
Rene Frank (University of Leeds, UK)
Host: Jan Bjålie
14:40 Coffee break
15:15 CANCER: Structural biology of Ras regulation: structure of human Neurofibromin
Marta Carroni (Stockholm University, Sweden)
Host: Nikolina Sekulić
15:50 VESICULAR TRANSPORT: Electron cryo-microscopy reveals the structure of membrane-remodeling proteins
Carsten Sachse (Forschungszentrum Jülich GmbH, Germany)
Host: Andreas Brech and Harald Stenmark
(Cancelled) 16:25 IMMUNOLOGY: In situ cryoEM of IgG3-mediated complement activation reveals novel structural insights into immune defence
Thomas H. Sharp (Leiden University Medical Center, Netherlands)
Host: Jan Terje Andersen
17:00 Closing
Nikolina Sekulić, Ute Krengel and Andreas Brech
Thursday, 19th October 2023 (Oslo Science Park/Radium hospital Oslo)
10:00 Remote demonstration of CryoTEM "Glacios 2" and its capabilities (Thermo Fisher)
NOTE: Venue change: Room Kino, Forskningsparken (Oslo Science Park)
Link to Teams stream: Click here to join the meeting
13:00 Lunch
14:00 Core facility for advanced electron microscopy and tomography – demo
Andreas Brech (K-building, Radium Hospital, seminar room 1) - registered participants only
Sponsors
- PX-Oslo
- BioCat
- Hydro
- Thermo Fisher
- Jeol
- Refeyn