The Chemical Biology Platform at NCMM has been involved in developing a HTS (High-Throughput Screening) 'Ring Test', which is part of a new study led by the collaborative group, 'TranslationTogether'. The study aims to address the issue of reproducibility in scientific research. FIMM is also involved in the project.
Currently, several initiatives are aimed at addressing these issues to improve reproducibility in foundational research laboratories. However, it appears that the reproducibility of preclinical experiments typically conducted by translational scientists has never been systematically investigated using methods such as high-throughput screening (HTS) of small molecule libraries.
The new pilot project aims to develop the first-ever HTS (High-Throughput Screening) reproducibility study. The results will be widely disseminated to improve the reliability of translational research practices.