The first global map of bipolar disorder

Researchers at NORMENT are part of an international consortium which recently published the largest MRI study to date on people with bipolar disorder. The study shows that patients have differences in brain regions that control inhibition and emotion.

Patients tend to have gray matter reductions in frontal brain regions involved in self-control, while sensory and visual regions are normal. (ENIGMA Bipolar Consortium/Derrek Hibar et al.)

Read more about the study here:

Scientists reveal the first ever map of the bipolar brain

 

Reference:

Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group.

Hibar, D. P., Westlye, L. T., Doan, N. T., Jahanshad, N., Cheung, J. W., Ching, C. R. K., Versace, A., Bilderbeck, A. C., Uhlmann, A., Mwangi, B., Kramer, B., Overs, B., Hartberg, C. B., Abe, C., Dima, D., Grotegerd, D., Sprooten, E., Boen, E., Jimenez, E., Howells, F. M., Delvecchio, G., Temmingh, H., Starke, J., Almeida, J. R. C., Goikolea, J. M., Houenou, J., Beard, L. M., Rauer, L., Abramovic, L., Bonnin, M., Ponteduro, M. F., Keil, M., Rive, M. M., Yao, N., Yalin, N., Najt, P., Rosa, P. G., Redlich, R., Trost, S., Hagenaars, S., Fears, S. C., Alonso-Lana, S., van Erp, T. G. M., Nickson, T., Chaim-Avancini, T. M., Meier, T. B., Elvsashagen, T., Haukvik, U. K., Lee, W. H., Schene, A. H., Lloyd, A. J., Young, A. H., Nugent, A., Dale, A. M., Pfennig, A., McIntosh, A. M., Lafer, B., Baune, B. T., Ekman, C. J., Zarate, C. A., Bearden, C. E., Henry, C., Simhandl, C., McDonald, C., Bourne, C., Stein, D. J., Wolf, D. H., Cannon, D. M., Glahn, D. C., Veltman, D. J., Pomarol-Clotet, E., Vieta, E., Canales-Rodriguez, E. J., Nery, F. G., Duran, F. L. S., Busatto, G. F., Roberts, G., Pearlson, G. D., Goodwin, G. M., Kugel, H., Whalley, H. C., Ruhe, H. G., Soares, J. C., Fullerton, J. M., Rybakowski, J. K., Savitz, J., Chaim, K. T., Fatjo-Vilas, M., Soeiro-de-Souza, M. G., Boks, M. P., Zanetti, M. V., Otaduy, M. C. G., Schaufelberger, M. S., Alda, M., Ingvar, M., Phillips, M. L., Kempton, M. J., Bauer, M., Landen, M., Lawrence, N. S., van Haren, N. E. M., Horn, N. R., Freimer, N. B., Gruber, O., Schofield, P. R., Mitchell, P. B., Kahn, R. S., Lenroot, R., Machado-Vieira, R., Ophoff, R. A., Sarro, S., Frangou, S., Satterthwaite, T. D., Hajek, T., Dannlowski, U., Malt, U. F., Arolt, V., Gattaz, W. F., Drevets, W. C., Caseras, X., Agartz, I., Thompson, P. M. and Andreassen, O. A.

Molecular Psychiatry, 2017, doi: 10.1038/mp.2017.73.

 

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Published May 4, 2017 2:27 PM - Last modified Jan. 31, 2022 9:08 PM
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